With the heterogeneity of the industry 4.0 world, and more generally of the Cyberphysical Systems realm, the quest towards a platform approach to solve the interoperability problem is front and centre to any system and system-of-systems project. Traditional approaches cover individual aspects, like data exchange formats and published interfaces. They may adhere to some standard, however they hardly cover the production of the integration layer, which is implemented as bespoke glue code that is hard to produce and even harder to maintain. Therefore, the traditional integration approach often leads to poor code quality, further increasing the time and cost and reducing the agility, and a high reliance on the individual development skills. We are instead tackling the interoperability challenge by building a model driven/low-code Digital Thread platform that 1) systematizes the integration methodology, 2) provides methods and techniques for the individual integrations based on a layered Domain Specific Languages (DSL) approach, 3) through the DSLs it covers the integration space domain by domain, technology by technology, and is thus highly generalizable and reusable, 4) showcases a first collection of examples from the domains of robotics, IoT, data analytics, AI/ML and web applications, 5) brings cohesiveness to the aforementioned heterogeneous platform, and 6) is easier to understand and maintain, even by not specialized programmers. We showcase the power, versatility and the potential of the Digital Thread platform on four interoperability case studies: the generic extension to REST services, to robotics through the UR family of robots, to the integration of various external databases (for data integration) and to the provision of data analytics capabilities in R.

Industry 4.0 is positioned at the junction of different disciplines, aiming to re-engineer processes and improve effectiveness and efficiency. It is taking over many industries whose traditional practices are being disrupted by advances in technology and inter-connectivity. In this context, enhanced agriculture systems incorporate new components that are capable of generating better decision making (humidity/temperature/soil sensors, drones for plague detection, smart irrigation, etc.) and also include novel processes for crop control (reproducible environmental conditions, proven strategies for water stress, etc.). At the same time, advances in model-driven development (MDD) simplify software development by introducing domain-specific abstractions of the code that makes application development feasible for domain experts who cannot code. XMDD (eXtreme MDD) makes this way to assemble software even more user-friendly and enables application domain experts who are not programmers to create complex solutions in a more straightforward way. Key to this approach is the introduction of high-level representations of domain-specific functionalities (called SIBs, service-independent building blocks) that encapsulate the programming code and their organisation in reusable libraries, and they are made available in the application development environment. This way, new domain-specific abstractions of the code become easily comprehensible and composable by domain experts. In this paper, we apply these concepts to a smart agriculture solution, producing a proof of concept for the new methodology in this application domain to be used as a portable demonstrator for MDD in IoT and agriculture in the Confirm Research Centre for Smart Manufacturing. Together with model-driven development tools, we leverage here the capabilities of the Nordic Thingy:53 as a multi-protocol IoT prototyping platform. It is an advanced sensing device that handles the data collection and distribution for decision making in the context of the agricultural system and supports edge computing. We demonstrate the importance of high-level abstraction when adopting a complex software development cycle within a multilayered heterogeneous IT ecosystem.

Background: In biomedical imaging research, experimental biologists generate vast amounts of data that require advanced computational analysis. Breakthroughs in experimental techniques, such as multiplex immunofluorescence tissue imaging, enable detailed proteomic analysis, but most biomedical researchers lack the programming and Artificial Intelligence (AI) expertise to leverage these innovations effectively. Methods: Cinco de Bio (CdB) is a web-based, collaborative low-code/no-code modelling and execution platform designed to address this challenge. It is designed along Model-Driven Development (MDD) and Service-Orientated Architecture (SOA) to enable modularity and scalability, and it is underpinned by formal methods to ensure correctness. The pre-processing of immunofluorescence images illustrates the ease of use and ease of modelling with CdB in comparison with the current, mostly manual, approaches. Results: CdB simplifies the deployment of data processing services that may use heterogeneous technologies. User-designed models support both a collaborative and user-centred design for biologists. Domain-Specific Languages for the Application domain (A-DSLs) are supported through data and process ontologies/taxonomies. They allow biologists to effectively model workflows in the terminology of their field. Conclusions: Comparative analysis of similar platforms in the literature illustrates the superiority of CdB along a number of comparison dimensions. We are expanding the platform’s capabilities and applying it to other domains of biomedical research.

Digitalisation and Industry 4.0 is changing the landscape of traditional industries and how they operate. Regulation, sustainability and staff shortages are challenging companies to alter their behaviour and business processes. It is now becoming essential for small to medium size enterprises (SMEs) to adapt to this change. This paper showcases how digitalisation can help with these new requirements by examining a case study with specific interest in collecting, monitoring and analysing data. The application was created for an SME registered in Ireland, and it will be used to showcase the difference between normal coding and low code development in the creation of these apps. This comparison is important because low code development will become essential for organisations in order to create novel IT-based approaches that will be used for the digital transformation of their specific business. Along with describing and reflecting on this process, we will also explain how this application is linked with the Sustainable Development Goals (SDGs) and how companies can integrate these goals in their business and IT choices.

While offering significant advantages, Metal Additive Manufacturing (MAM) faces persistent challenges in process stability and reproducibility. Data-driven models using in-situ sensor data enable real-time quality control and defect mitigation but are difficult to deploy for resource-constrained manufacturers. This work presents a Digital Shadow–informed Decision Support System (DSS) designed to integrate machine learning (ML) capabilities through a Service-Oriented Architecture (SOA) and Low-Code/No-Code (LCNC) development methodologies. The approach facilitates rapid creation and deployment of modular analysis services for MAM, allowing small and medium enterprises (SMEs) to implement adaptive, data-driven diagnostic and decision-support tools for reliable MAM based production.