Ewa Grudzińska

Dr. Ewa Grudzińska

orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
21 January 2018 in Journal of Ophthalmology
Verified
Journal Article
Open access
PDF file
EGEwa Grudzińska
Ewa Grudzińska
MMMonika Marzanna Modrzejewska
Monika Marzanna Modrzejewska
Myopia is the most common refractive error and the subject of interest of various studies assessing ocular blood flow. Increasing refractive error and axial elongation of the eye result in the stretching and thinning of the scleral, choroid, and retinal tissues and the decrease in retinal vessel diameter, disturbing ocular blood flow. Local and systemic factors known to change ocular blood flow include glaucoma, medications and fluctuations in intraocular pressure, and metabolic parameters. Techniques and tools assessing ocular blood flow include, among others, laser Doppler flowmetry (LDF), retinal function imager (RFI), laser speckle contrast imaging (LSCI), magnetic resonance imaging (MRI), optical coherence tomography angiography (OCTA), pulsatile ocular blood flowmeter (POBF), fundus pulsation amplitude (FPA), colour Doppler imaging (CDI), and Doppler optical coherence tomography (DOCT). Many researchers consistently reported lower blood flow parameters in myopic eyes regardless of the used diagnostic method. It is unclear whether this is a primary change that causes secondary thinning of ocular tissues or quite the opposite; that is, the mechanical stretching of the eye wall reduces its thickness and causes a secondary lower demand of tissues for oxygen. This paper presents a review of studies assessing ocular blood flow in myopes.

1 June 2021 in Clinical Ophthalmology
Verified
Journal Article
Open access
PDF file
EGEwa Grudzińska
Ewa Grudzińska
MMMonika Marzanna Modrzejewska
Monika Marzanna Modrzejewska
Purpose: To assess pattern electroretinogram (PERG) recordings in patients with axial myopia with a special focus on the correct interpretation of findings. Patients and Methods: Sixty patients divided into three groups according to the spherical equivalent of refractive error (group 1, error − 3 D to − 6 D; group 2, error > − 6 D; and controls, error − 1 D to +1 D) were examined. Data for the right eye of every patient were considered in the statistical analysis. All patients had a full ophthalmic examination including the measurement of visual acuity, intraocular pressure, degree of refractive error, axial length, biomicroscopic evaluation of the anterior segment, fundoscopy and PERG. The differences of basic parameters and P50 and N95 amplitudes as well as P50 implicit time between groups were studied. Correlations between P50 and N95 amplitudes and P50 implicit time were axial length and refractive error was established. Results: The P50 amplitude, N95 amplitude and P50 peak time differed significantly between the groups (P< 0.01). No significant differences were found for the N95/P50 ratio. Significantly lower P50 and N95 amplitudes (r=− 0.42, P< 0.01; r=− 0.42, P< 0.01) and increased P50 peak time (r=0.64, P< 0.01) correlated with elongated axial length. A 1-mm increase in axial length corresponded with a 0.41 μV decrease in the P50 amplitude and 0.55 μV reduction of the N95 amplitude. There was also 1.11 ms increase of P50 wave peak time per 1 mm increase of axial length. Significantly lower amplitudes and longer peak times are associated with increased axial length and increased refractive error. Conclusion: According to results observed in this study, the correct interpretation of PERG recordings requires the consideration of axial length.

13 February 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
EGEwa Grudzińska
Ewa Grudzińska
MDMagdalena Anna Durajczyk
Magdalena Anna Durajczyk
MGMarek Grudziński
Marek Grudziński
ŁMŁukasz Marchewka
Łukasz Marchewka
MMMonika Marzanna Modrzejewska
Monika Marzanna Modrzejewska
Background: The variability of the obtained results of manual tests assessing the angle of strabismus depends on the experience, skills, and training of the examiner. The authors hope that this new measuring device will provide a more sensitive and repeatable method for detecting small strabismus angles compared to the gold standard—PCT. The purpose of this article is to present an innovative strabismus angle demonstration device, called Strabiscan, to provide automated measurements of eye deviation and to compare the obtained results of these measurements to the traditional manual method. Methods: For patients with manifest strabismic disease (n = 30) and a group of healthy subjects (n = 30), a detailed history was taken and routine ophthalmologic examinations were performed, including best-corrected distance visual acuity, assessment of refractive error using an autorefractometer after cycloplegia, biomicroscopic evaluation of the anterior segment of the eye and evaluation of the eye fundus by indirect ophthalmoscopy. Subsequently, each patient and healthy subject was subjected to a prismatic cover–uncover test using a manual method, after which the presence of strabismus was detected and its angle assessed using a Strabiscan demonstration device. Results: In the control group using the Strabiscan demonstration device, small-angle latent strabismus ≤ 3DP was diagnosed in 83% of patients, while >3DP was found in 13%. In contrast, using the prismatic cover–uncover test, latent strabismus ≤ 3DP was diagnosed in only 13% of patients, and latent strabismus with an angle > 3DP was found in 13% of patients. No statistically significant differences were noted in the measurements of strabismus angles made by the different methods. Conclusions: The Strabiscan demonstration device allows quick and accurate assessment of the strabismus angle. Compared to the prismatic cover–uncover test, it has a higher sensitivity for detecting low-angle latent strabismus. Measurements with the Strabiscan do not require the presence of additional assistants for the test.

4 December 2022 in Documenta Ophthalmologica
Verified
Journal Article
Open access
PDF file
EGEwa Grudzińska
Ewa Grudzińska
WLWojciech Lubiński
Wojciech Lubiński
MMMonika Marzanna Modrzejewska
Monika Marzanna Modrzejewska
Purpose: This work aims at assessing whether electrophysiological functional changes in the macular region appear in medium myopia, even in the presence of a normal macular OCT scan and how axial length correlates with macular OCT parameters in medium myopia. Methods: The study included right eyes of 17 patients with myopia of medium degree (SE < − 6D to > − 3D). Control group consisted of 20 eyes of patients of age and sex that matched healthy controls with normal macular and optic nerve OCT results and normal axial length. Full ophthalmic examination (the distance best-corrected visual acuity, intraocular pressure, refractive error, the anterior and posterior segment of the eye in a slit lamp, the axial length of the eyeball) with OCT of the macular and optic disk and the PERG test were performed in the study and control groups. Only the patients with normal ophthalmic and OCT examination results were qualified. The interview covering questions on risk factors of myopia onset and progression such as prematurity, family history of myopia was carried out in both groups. In myopic group, the question relating to time of near work was also asked. Study and control groups were tested with the use of Shapiro–Wilk, Mann–Whitney, Student’s t test, Pearson and Spearman's rank correlation tests. Results: AL was significantly longer in myopia group (p < 0.01), and SE value was lower (p < 0.01). Longer implicit time of P50 was found in the study group, but amplitudes of P50 and N95 waves were not significantly reduced (p < 0.05). AL showed correlations with P50 implicit time (p < 0.05) and with reduction in retinal fiber nerve layer and ganglion cells and inner plexus layer (p < 0.05). Conclusion: Patients with myopia of medium degree have a dysfunction of retinal cone system of the macular region even when OCT scans show no abnormalities. Elongation of AL correlates with reduction in retinal fiber nerve layer and ganglion cells and inner plexus layer. Longitudinal follow-up studies may answer the question whether this increase in implicit time may be indicative of a faster myopia progression or of myopic retinal pathology, i.e., whether it may help to determine which patient would benefit from earlier or more intensive management of myopia progression.

9 January 2024 in Preprints.org
Verified
Preprint
Open access
PDF file
EGEwa Grudzińska
Ewa Grudzińska
MDMagdalena Anna Durajczyk
Magdalena Anna Durajczyk
MGMarek Grudziński
Marek Grudziński
ŁMŁukasz Marchewka
Łukasz Marchewka
MMMonika Marzanna Modrzejewska
Monika Marzanna Modrzejewska
Background: The variability of the obtained results of manual tests assessing the angle of strabismus depends on the experience, skills, and training of the examiner. The authors hope that the new measuring device will provide a more sensitive and repeatable method for detecting small strabismus angles compared to the gold standard – PCT. The purpose of this article is to present an innovative strabismus angle demonstration device, called Strabiscan, to present automated measurements of eye deviation, and to compare the obtained results of these measurements to the traditional manual method. Methods: In patients with the manifest strabismic disease (n = 30) and a group of healthy subjects (n = 30), a detailed history was taken and routine ophthalmologic examinations were performed, including best-corrected distance visual acuity, assessment of refractive error using an autorefractometer after cycloplegia, biomicroscopic evaluation of the anterior segment of the eye, and evaluation of the eye fundus by indirect ophthalmoscopy. Subsequently, each patient and healthy subjects were subjected to a prismatic cover-uncover test using a manual method, and then the presence of strabismus was detected and its angle assessed using demonstration Strabiscan device. Results: In the control group, using the Strabiscan demonstration device, small-angle latent strabismus ≤3DP was diagnosed in 83% of patients, and >3DP in 13%. In contrast, using the prismatic cover-uncover test, latent strabismus ≤3DP was diagnosed in only 13% of patients, and latent strabismus with an angle >3DP in 13% of patients. No statistically significant differences were noted in the measurements of strabismus angles made by the different methods. Conclusions: The Strabiscan demonstration device allows quick and accurate assessment of the strabismus angle. Compared to the prismatic cover-uncover test, it has a higher sensitivity for detecting low-angle latent strabismus. Measurements with the Strabiscan do not require the presence of additional co-assistants for the test.

1 December 2021 in OphthaTherapy. Therapies in Ophthalmology
Verified
Journal Article
Open access
PDF file
MDMagdalena Durajczyk
Magdalena Durajczyk
EGEwa Grudzińska
Ewa Grudzińska
AOAleksandra Obszańska
Aleksandra Obszańska
MMMonika Marzanna Modrzejewska
Monika Marzanna Modrzejewska
Krótkowzroczność jest główną przyczyną zaburzeń widzenia, będąc najczęstszą wadą refrakcji. Istnieje wiele podziałów krótkowzroczności uwzględniających wielkość wady refrakcji, dziedziczność, moment pojawienia się wady refrakcji, stan szczegółów dna oka czy długość osiową gałki ocznej. W literaturze istnieje duża niespójność w tym zakresie. Można znaleźć wiele terminów opisowych, jak również klasyfikacji określających rodzaje krótkowzroczności, co prowadzi do trudności przy porównywaniu wyników badań. Celem artykułu jest przedstawienie aktualnej definicji i podziału krótkowzorczności na podstawie przeglądu piśmiennictwa PubMed z ostatnich 5 lat.