Cruciferous vegetables such as cauliflower and radish contain isothiocyanates exhibiting chemoprotective effects in vitro and in vivo. This research aimed to assess the impact of cauliflower (CIE) and radish (RIE) isothiocyanate extracts on the metabolic activity, intracellular reactive oxygen species (ROS), and LDH production of selected human colorectal adenocarcinoma cells (HCT116 and HT-29 for early and late colon cancer development, respectively). Non-cancerous colon cells (CCD-33Co) were used as a cytotoxicity control. The CIE samples displayed the highest allyl isothiocyanate (AITC: 12.55 µg/g) contents, whereas RIE was the most abundant in benzyl isothiocyanate (BITC: 15.35 µg/g). Both extracts effectively inhibited HCT116 and HT-29 metabolic activity, but the CIE impact was higher than that of RIE on HCT116 (IC₅₀: 0.56 mg/mL). Assays using the half-inhibitory concentrations (IC₅₀) of all treatments, including AITC and BITC, displayed increased (p < 0.05) LDH (absorbance: 0.25–0.40 nm) and ROS release (1190–1697 relative fluorescence units) in both cell lines. BITC showed the highest in silico binding affinity with all the tested colorectal cancer molecular markers (NF-kB, β-catenin, and NRF2-NFE2). The theoretical evaluation of AITC and BITC bioavailability showed high values for both compounds. The results indicate that CIE and RIE extracts display chemopreventive effects in vitro, but additional experiments are needed to validate their effects.

Stress is a condition that has been related to the development of risk behaviors for health such as sugar-sweetened beverages (SSBs) consumption. The aim of this study was to examine the link between SSBs consumption and perceived stress level in university students. This was an observational, cross-sectional and single-time-point study where the subjects were recruited as a non-probabilistic sample of first-year university students. The students reported their SSBs consumption through a validated questionnaire, as well as their perceived stress level, evaluated through the Cohen scale. Comparisons were made between the means of all variables. Factorial analysis of variance was conducted to explore the effect of the variables’ interaction on the stress level. One-way analysis of variance was performed to assess differences between the sexes. Men consumed more SSBs (6101.17 ± 3772.50 mL/week) compared to women (4294.06 ± 3093.8 mL/week). However, women had higher scores of perceived stress and showed a strong association of stress with the SSBs consumption pattern (r and p-value). This study shows for the first time the association that exists between stress and SSBs consumption and indicates that it is related to sex in the young population.

It has been proposed that the consumption of foods high in sugar or fat may cause addictive behavior. The aim of this study was to adapt and validate a soft drink addiction scale that can be used in future studies and to strengthen the proposal of food addiction with the hypothesis that people with high consumption of soft drinks have similar characteristics to people who consume abuse drugs. A non-probabilistic convenience sample of 394 Mexican participants answered a soft drinks’ consumption frequency questionnaire, an addiction scale, and a self-efficacy scale for soft drinks’ consumption. Additionally, anthropometric measurements were taken. The addiction scale showed three factors with an adequate reliability (Cronbach’s alpha coefficient = 0.903), as well as construct validity and criterion validity with the self-efficacy scale and total body fat percentage on soft drinks, mainly those with substantial caloric content. Additionally, the results showed a predictive value for soft drink consumption, strengthening its validity. This scale is useful to identify and evaluate the characteristic patterns of a substance addiction. The total reliability indicates that the items as a whole are correlated with each other and that the scale is stable to be used over time. This is the first study that evaluates the addictive characteristics of soft drink consumption through a scale, and it represents an advance in the exploration of the behavioral sciences field and an important tool for the creation of public health policies, mainly in countries with a high consumption of these beverages.

La prediabetes es una condición clínica previa a que se declare la diabetes mellitus tipo 2 (DM2) en la que existe una elevación de la glucosa que va progresando a niveles muy altos característicos de la DM2. Así, la prediabetes es una categoría intermedia en la que ya se comienzan a presentar niveles prominentes de glucosa y quienes la padecen es muy probable que desarrollen DM2. La Encuesta Nacional de Salud y Nutrición de 2022 reportó una prevalencia de 22.1% de personas con este padecimiento, que en proporción son dos de cada 10 adultos con edades de 20 años o más, los cuales tienen un mayor riesgo de desarrollar DM2.

An increase in fat-free mass (FFM) improves athletic performance. The aim of this study was to determine if a decrease in the FFM, expressed as the AKS index, is associated with physiological alterations after a training period in swimmers between 8-15 years old. Forty-two swimmers participated in this study, after 15 weeks of training the swimmers were divided into two groups, those who decreased (A) and those who increased FFM (B). In group A there was a decrease in both, body weight and muscle, mass while in group B there was an increase in body weight. We found that group A showed a reduction in lymphocytes count, in addition to an increase in serum urea, a decrease in VO2, and a decrease in their 1 min recovery. We showed here that a reduction in FFM is positively associated with physiological alterations that reduce athletic performance.

Los edulcorantes no calóricos son sustancias químicas que dan un sabor dulce a las bebidas y alimentos, y debido a ello son aprovechados por la industria alimentaria como aditivos. No proporcionan calorías o energía, sólo el dulzor; por lo tanto, no elevan el azúcar en la sangre, condición que los hace ideales para las personas que presentan alguna enfermedad como diabetes, sobrepeso y obesidad. Los edulcorantes no calóricos se pueden conseguir en forma comercial en sobres, para agregar a las bebidas caseras o en los productos que tienen la leyenda “Contiene edulcorantes”. Es importante que aprendamos a consumirlos adecuadamente sin que afecte nuestra salud.