Apostolos G. Pitoulias

Dr. Apostolos G. Pitoulias

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Research Focus & Metrics

Academic Career Length

26Years (2001-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2016 in Journal of Vascular Surgery
Verified
Journal Article
Closed access
Konstantinos DonasKonstantinos Donas
Konstantinos Donas
GTGiovanni B. Torsello
Giovanni B. Torsello
GPGianluca Piccoli
Gianluca Piccoli
APApostolos G. Pitoulias
Apostolos G. Pitoulias
GTGiovanni Federico Torsello
Giovanni Federico Torsello
DGDaniele Gasparini
Daniele Gasparini

1 October 2007 in Journal of Vascular Surgery
Verified
Journal Article
Closed access
APApostolos G. Pitoulias
Apostolos G. Pitoulias
KDKonstantinos P. Donas
Konstantinos P. Donas
SSStefan Schulte
Stefan Schulte
SHSvante Horsch
Svante Horsch
DPDimitrios K. Papadimitriou
Dimitrios K. Papadimitriou

1 October 2010 in Journal of Endovascular Therapy
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Journal Article
Closed access
PDF file
KDKonstantinos P. Donas
Konstantinos P. Donas
GTGiovanni Torsello
Giovanni Torsello
MAMartin Austermann
Martin Austermann
ASArne Schwindt
Arne Schwindt
Nicola TroisiNicola Troisi
Nicola Troisi
APApostolos G. Pitoulias
Apostolos G. Pitoulias
Purpose: To present our initial experience with the use of chimney grafts in endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAAs) with challenging anatomy. Methods: Among 390 EVAR cases performed at our institution between November 2008 and February 2010, 15 patients (all men; mean age 81.8 years) underwent EVAR with synchronous placement of chimney grafts. The chimney technique involved placing covered stents parallel to the main aortic stent-graft to preserve or rescue flow to aortic branch vessels while extending the proximal fixation zone. All patients presented with pararenal aortic aneurysms with short necks (between 0 and 10 mm long) that required either suprarenal clamping to tailor a proximal anastomosis in open repair or suprarenal fixation to anchor an endoprosthesis. Chimney grafts were implanted into 10 left renal and 5 right renal arteries. Results: The immediate technical success was 100%. One early type II endoleak due to retrograde flow from the inferior mesenteric artery was detected and is under surveillance. Mean follow-up was 6.8 months (range 1–13). One chimney graft occluded 45 days postoperatively; the patient underwent open thrombectomy of the left renal artery and iliorenal bypass. The creatinine value at discharge was 1.6 mg/dL, and resting renal scintigraphy showed 36% perfusion for the left kidney and 64% for the right kidney. During follow-up, no patient required hemodialysis; no aneurysm-related deaths were noted. Conclusion: This limited experience demonstrates that the use of abdominal chimney grafts is feasible and safe. Long-term results in larger patient cohorts are needed evaluate the utility of this alternative endovascular technique.

1 December 2012 in Journal of Endovascular Therapy
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Journal Article
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PDF file
KDKonstantinos P. Donas
Konstantinos P. Donas
GTGiovanni Torsello
Giovanni Torsello
TBTheodosios Bisdas
Theodosios Bisdas
NONani Osada
Nani Osada
ESEva Schönefeld
Eva Schönefeld
APApostolos G. Pitoulias
Apostolos G. Pitoulias
Purpose To compare short-term outcomes between fenestrated and chimney endografts for pararenal aortic pathologies. Methods An English-language literature search up to January 2012 found 129 articles evaluating the immediate outcomes of endovascular repair of degenerative juxta-/suprarenal aortic aneurysms, type I endoleaks, and para-anastomotic aneurysms using the chimney technique or fenestrated endografts. Data concerning thoracoabdominal aortic aneurysms, ruptured aneurysms, and reports with <5 cases were excluded (n=84). An additional 28 articles were excluded for insufficient data, leaving 17 articles for review: 5 dealing with chimney grafts in 123 patients with pararenal aortic pathologies and 12 presenting data on 631 patients undergoing fenestrated stent-grafting. The composite endpoints were 30-day mortality, deterioration of renal function, new postoperative dialysis dependence, and endoleak rate. Results Cumulative 30-day procedure-related mortality was 0.58% (95% CI 0.0% to 2.93%) for the chimney group (n=3) and 1.17% (95% CI 0.26% to 2.09%, p=0.645) for the f-EVAR group (n=9). In the f-EVAR group, 86 (9.67%;95% CI 4.77% to 14.57%) patients suffered from postoperative renal impairment vs. 16 (12.43%) patients in the chimney group (95% CI 2.39% to 22.48%, p=0.628). In the chimney group, 4 (0.57%;95% CI 0.0% to 2.94%) patients required persistent postoperative dialysis in contrast to the 1.33% (95% CI 0.29% to 2.37%, p=0.567) rate (n=9) in patients undergoing f-EVAR. There were also no significant differences recorded in the endoleak rate: 1.93% (95% CI 0.0% to 4.82%) of the chimney patients had a persistent type Ia endoleak vs. 2.06% (95% CI 0.69% to 3.43%) for the f-EVAR group (p=0.939). For type II endoleaks, the rates were 2.16% (95% CI 0.0% to 10.77%) for the chimney group vs. 6.88% (95% CI 1.92% to 11.83%) for the f-EVAR group (p=0.352). No patient in the chimney group had a type III endoleak, and the rate was low in the f-EVAR group (0.32%,95% CI 0.0% to 0.91%, p=0.079). Conclusion No statistically significant differences were found between the two endovascular approaches for pararenal aortic pathologies in terms of 30-day mortality, renal impairment, or endoleak. These findings support the assumption that chimney grafts may be a reliable alternative in the treatment of pararenal aortic pathologies.

1 December 2017 in Journal of Vascular Surgery
Verified
Journal Article
Closed access
APApostolos G. Pitoulias
Apostolos G. Pitoulias
AVAndres Reyes Valdivia
Andres Reyes Valdivia
SHSuteekhanit Hahtapornsawan
Suteekhanit Hahtapornsawan
GTGiovanni Torsello
Giovanni Torsello
APApostolos G. Pitoulias
Apostolos G. Pitoulias
KDKonstantinos P. Donas
Konstantinos P. Donas

1 October 2011 in Journal of Endovascular Therapy
Verified
Journal Article
Closed access
PDF file
BGBernd Gehringhoff
Bernd Gehringhoff
GTGiovanni Torsello
Giovanni Torsello
APApostolos G. Pitoulias
Apostolos G. Pitoulias
MAMartin Austermann
Martin Austermann
KDKonstantinos P. Donas
Konstantinos P. Donas
Purpose To present a clinical experience with the use of chimney grafts in the endovascular repair of aortic arch pathologies involving the supra-aortic branches. Methods The chimney technique consists of endovascular stent or stent-graft placement parallel to the main aortic stent-graft in order to preserve or rescue flow to aortic branch vessels and to allow proximal extension of endograft fixation zones. Between April 2009 and January 2011, 9 patients (7 men; mean age 58 years, range 39–76) had chimney grafts installed to the left subclavian artery (LSA) or left common carotid artery (LCCA) during urgent thoracic endovascular aortic repair (TEVAR) of 5 aortic arch aneurysms, a mobile aortic thrombus with peripheral embolism, symptomatic type B dissection, penetrating aortic ulcer, and persistent type I endoleak after TEVAR. Eight chimney grafts were implanted into the LSA in 6 patients and 5 into the LCCA in the other 3 patients. Results The immediate technical success was 88.9%. The post-TEVAR type I endoleak persisted despite the chimney graft; the patient underwent surgical arch replacement. One patient died within 30 days due to cardiac insufficiency. There were 2 access site complications requiring surgery (brachial artery pseudoaneurysm and heavily calcified femoral artery puncture site). Over a median follow-up of 15 months (range 4–22), all chimney grafts remained patent in the 7 surviving and successfully treated patients. Conclusion The use of chimney grafts in selected aortic arch pathologies with involvement of supra-aortic branches is safe and feasible. Long-term results and large series are needed in order to draw robust conclusions regarding this promising alternative endovascular technique.