Pogacian-Maier Alexandra-Camelia

Dr. Pogacian-Maier Alexandra-Camelia


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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31 January 2024 in Medicina
Verified
Journal Article
Open access
PDF file
PAPogacian-Maier Alexandra-Camelia
Pogacian-Maier Alexandra-Camelia
AMAlexandru Mester
Alexandru Mester
RMRares-Luca Morariu
Rares-Luca Morariu
RCRadu Septimiu Campian
Radu Septimiu Campian
Paul Andrei ȚențPaul Andrei Țenț
Paul Andrei Țenț
Background and Objectives: The aim of this systematic review was to assess the efficiency of using allografts for sinus lift. Materials and Methods: This systematic review was written under the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and recommendation of the Cochrane Handbook for Systematic Reviews of Interventions. Three electronic databases were screened until October 2023. The risk of bias was assessed according to the Strengthening the Reporting of Observational studies in Epidemiology (STROBE) guidelines. Statistical analysis was performed for median bone volume and implant survival rate. Results: From 321 articles retrieved, 7 articles were included in this review. A comparison between freeze-dried bone allograft (FDBA) and deproteinized bovine bone (DBB) for mean bone volume indicated a weighted mean difference (WMD) of −0.17 [−0.69, 0.36] (95% confidence interval (CI)), p = 0.53. For implant survival rate, a comparison was made between FDBA and autogenous bone indicating a risk ratio (RR) of 1.00 [0.96, 1.05] (95% CI), p = 1.00. Conclusions: The available evidence suggested that allograft bone can be used in sinus lift procedures. The results obtained are insufficient to compare with other types of bone graft, requiring a longer follow-up time. Future clinical trials are needed in order to evaluate the advantages of using allograft bone.

9 October 2025 in Biomedicines
Verified
Journal Article
Open access
PDF file
PAPogacian-Maier Alexandra-Camelia
Pogacian-Maier Alexandra-Camelia
RCRadu Septimiu Campian
Radu Septimiu Campian
AMAlexandru Mester
Alexandru Mester
MMMarioara Moldovan
Marioara Moldovan
IPIoan Petean
Ioan Petean
DEDragos Ene
Dragos Ene
Background: This study aimed to evaluate the impact of different chemical treatments on titanium implant surfaces and their biological compatibility. Methods: Titanium dental implants were immersed in Ringer’s solution, hydrogen peroxide (3%), citric acid (40%), EDTA (40%), or a citric–phosphoric acid mixture. Electrochemical behavior was analyzed using open-circuit potential monitoring and electrochemical impedance spectroscopy over 168 h. Cytocompatibility was assessed by culturing human gingival mesenchymal stem cells (MSCs) directly on treated implants and in conditioned media, followed by viability evaluation through CCK-8 assays. Results: Citric acid and Ringer’s solution preserved passive film stability and supported high MSC viability (>75%) with minimal cytotoxic effects. Hydrogen peroxide and the citric–phosphoric acid mixture caused pronounced surface corrosion, decreased impedance stability, and significantly reduced cell viability (57–65%). EDTA-treated surfaces showed intermediate results, with moderate viability but impaired cell adhesion. Conclusion: The findings highlight the dual influence of chemical decontamination on implant stability and biological response. Citric acid and Ringer’s solution appear to be safer protocols for surface decontamination, whereas hydrogen peroxide and mixed acid treatments should be applied with caution due to their detrimental electrochemical and cytotoxic effects.

15 September 2024 in Romanian Journal of Oral Rehabilitation
Verified
Journal Article
Open access
RSRadu Mircea Sireteanu-Cucui
Radu Mircea Sireteanu-Cucui
ASAlina Stefanache
Alina Stefanache
CHClara Haddad
Clara Haddad
LRLaura Ecaterina Romila
Laura Ecaterina Romila
GABRIELA CALIN (MIHALACHE)GABRIELA CALIN (MIHALACHE)
GABRIELA CALIN (MIHALACHE)
PAPogacian-Maier Alexandra-Camelia
Pogacian-Maier Alexandra-Camelia
Aim of the Study: This study aims to provide a comprehensive comparison of different inorganic dental cements by reviewing existing literature, discussing their properties, applications, and advancements, and outlining future prospects in this field. Introduction: Dental cements play a critical role in restorative dentistry, providing essential properties like adhesion, biocompatibility, and mechanical strength necessary for the success and longevity of dental restorations. Among the inorganic dental cements, zinc phosphate, glass ionomer, and resin-modified glass ionomer cements are widely used due to their distinct advantages and specific applications. Methods and Materials: A thorough literature review was conducted, analyzing peer-reviewed studies and clinical reports on zinc phosphate, glass ionomer, and resin-modified glass ionomer cements. The analysis focused on comparing their chemical compositions, mechanical properties, adhesion capabilities, biocompatibility, and clinical performance. Results: Zinc phosphate cement is noted for its high compressive strength but lacks adhesion to tooth structures and can cause postoperative sensitivity. Glass ionomer cement offers fluoride release and good adhesion but has lower mechanical strength. Resin-modified glass ionomer cement combines the benefits of both, providing enhanced mechanical properties, moisture resistance, and fluoride release. Conclusions: Inorganic dental cements each present unique benefits and limitations. Zinc phosphate is best for its mechanical strength, glass ionomer for caries prevention, and resin-modified glass ionomer for a balanced performance. Future advancements in nanotechnology and adhesive formulations promise further improvements in dental cement properties, enhancing restorative dentistry outcomes.

20 December 2024 in Romanian Journal of Oral Rehabilitation
Verified
Journal Article
Open access
GLGiurgiu Cristian Levente
Giurgiu Cristian Levente
GMGeorge Morarasu
George Morarasu
NBNicolae Baranov
Nicolae Baranov
PAPogacian-Maier Alexandra-Camelia
Pogacian-Maier Alexandra-Camelia
RSRadu-Mircea Sireteanu-Cucui
Radu-Mircea Sireteanu-Cucui
ASAlina Stefanache
Alina Stefanache
Aim of the Study: This review aims to investigate the pharmacologically induced discoloration of teeth and bones, focusing on how various medications affect the coloration of tooth enamel and dentin. The study seeks to provide insight into the mechanisms behind intrinsic and extrinsic discoloration and their clinical implications. Materials and Methods: A comprehensive literature search was conducted using databases such as PubMed, Google Scholar, and Web of Science. Keywords related to tooth discoloration and medications were used to identify relevant studies, including clinical trials and case reports published between 1990 and 2023. Studies that focused on medication-related discoloration of enamel and bone were analyzed to explore the biochemical interactions between drugs and dental tissues. Results and Discussion: The review identified several classes of medications, including tetracyclines, fluoride, antineoplastic agents, antimalarials, and iron supplements, as primary contributors to both intrinsic and extrinsic tooth discoloration. Tetracycline binds to calcium during tooth formation, leading to permanent discoloration. Fluoride can cause enamel hypomineralization, resulting in fluorosis. Antimalarials and iron supplements cause extrinsic stains due to complex formation with enamel minerals. Treatment options range from professional cleaning and bleaching to more invasive procedures like veneers and crowns, depending on the type and severity of the discoloration. Conclusion: Medication-induced tooth discoloration presents significant clinical challenges due to its varied mechanisms, including intrinsic staining from systemic incorporation of drugs and extrinsic staining from surface agents. Early identification of high-risk medications, preventive measures, and appropriate treatment are essential to minimize aesthetic and psychological impacts. While extrinsic stains are easier to manage, intrinsic discoloration often requires restorative approaches, such as veneers or crowns, for effective resolution.

15 March 2024 in Romanian Journal of Oral Rehabilitation
Verified
Journal Article
Open access
SBSorana-Maria Bucur
Sorana-Maria Bucur
DCDorin Ioan Cocoș
Dorin Ioan Cocoș
PAPogacian-Maier Alexandra-Camelia
Pogacian-Maier Alexandra-Camelia
MPMariana Păcurar
Mariana Păcurar
CGCarmen Galea
Carmen Galea
Aim of the study: to evaluate a reliable and user-friendly index to predict the surgical difficulty of the extractions of mesioangular impacted mandibular third molars. Material and method: Our retrospective study included 237 patients aged 16 to 40 years, with an average of 27.3. The patients were categorized into three different age groups, under 20 years, between 20 and 30 years, and between 30 and 40 years. Depending on the values of the angle of the long axis of the lower third molar with the axis of the mandibular canal we divided the cases into three groups: the first with an angle of 0°-30°, the second with an angle between 30°-60° and the last with values between 60°-90°. Another studied parameter was the operating time. Results: There were 67 patients under 20 years old (28.3%), 113 between 20 and 30 (47.7%), and (24%) between 30 and 40. 35% of the group were men, while 65% were women. The chi-square test showed a negative correlation between the duration of the surgical intervention and the molar angulation (p=0.049). There was no statistically significant correlation between the duration of the extraction and the age of the patients (p=0.941).Conclusion: Based on the results of our study, we can propose a larger one to confirm the findings of your research.

9 April 2025 in Romanian Journal of Oral Rehabilitation
Verified
Journal Article
Open access
PAPogacian-Maier Alexandra-Camelia
Pogacian-Maier Alexandra-Camelia
RCRadu Septimiu Campian
Radu Septimiu Campian
AMAlexandru Mester
Alexandru Mester
APAndra Piciu
Andra Piciu
Background and Aim: Periodontal disease and hepatitis C virus (HCV) infection are chronic conditions with systemic and oral health implications. This study aimed to evaluate the effects of non-surgical periodontal treatment combined with direct-acting antiviral (DAA) therapy in HCV patients. Materials and Methods: A prospective interventional study was conducted with 80 participants divided into four groups based on periodontal and HCV status. Periodontal parameters (probing depth (PD), clinical attachment loss (CAL), oral hygiene index (OHI), and bleeding on probing (BOP)) were measured at baseline, 3 months, and 6 months. Results: Significant improvements in OHI and BOP were observed across all groups, particularly in HCV patients receiving DAA therapy combined with periodontal treatment. PD and CAL values remained stable, suggesting effective management of periodontal disease progression. Conclusion: This study indicates the importance of an integrated approach to managing HCV and periodontal disease, highlighting the synergistic effects of DAA therapy and non-surgical periodontal treatment.