Tomohito Horimoto

Mr. Tomohito Horimoto

orcid

Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 March 2024 in Nutrients
Verified
Journal Article
Open access
PDF file
Ryota WakayamaRyota Wakayama
Ryota Wakayama
ADAdam Drewnowski
Adam Drewnowski
THTomohito Horimoto
Tomohito Horimoto
YSYoshie Saito
Yoshie Saito
TYTao Yu
Tao Yu
STSatoshi Takasugi
Satoshi Takasugi
This study introduces the Meiji Nutritional Profiling System (Meiji NPS), which was specifically designed to respond to age-related shifts in nutrient requirements among Japanese adults (<65 years old) and older adults (≥65 years old). Japan has one of the most aged societies in the world. The health issues of interest are malnutrition and lifestyle-related diseases among adults and frailty among older adults. Two versions of the NPS were developed based on nutrients to encourage (protein, dietary fibers, calcium, iron, and vitamin D), food groups to encourage (fruits, vegetables, nuts, legumes, and dairy), and nutrients to limit (energy, saturated fatty acids, sugars, and salt equivalents). The Meiji NPS for older adults did not include iron or saturated fatty acids. The algorithms were based on the Nutrient-Rich Foods Index (NRF). The convergent validity between the Meiji NPS and the existing NPSs for the same foods was confirmed using Spearman’s correlation coefficients (NRF: r = 0.67 for adults and r = 0.60 for older adults; Health Star Rating: r = 0.64 for adults and r = 0.61 for older adults). The Meiji NPS may be useful for nutritional evaluation and reformulation of food products, tailored to adults and older adults to ameliorate health issues in Japan.

14 August 2024 in Nutrients
Verified
Journal Article
Open access
PDF file
Ryota WakayamaRyota Wakayama
Ryota Wakayama
ADAdam Drewnowski
Adam Drewnowski
THTomohito Horimoto
Tomohito Horimoto
TYTao Yu
Tao Yu
YSYoshie Saito
Yoshie Saito
STSatoshi Takasugi
Satoshi Takasugi
Serving size may be the appropriate reference for calculating food nutritional value. We aimed to assess the nutritional values of Japanese foods based on serving sizes rather than per 100 g by adapting the Meiji Nutritional Profiling System (Meiji NPS). Given the variability in serving sizes across countries, we used Japanese serving sizes to calculate the Meiji NPS scores. We confirmed the convergent validity of the Meiji NPS scores per serving size with the Nutrient-Rich Food Index 9.3 using Spearman’s correlation coefficients (r = 0.51, p < 0.001). Food groups recommended by official guidelines, such as pulses, nuts and seeds, fish and seafood, fruits, vegetables, and milk and milk products, scored relatively high. Furthermore, the nutrient density scores of food items with small serving sizes, such as mushrooms, algae, seasonings, and fats and oils, were moderated when calculated by per serving size, despite having considerably higher or lower scores per 100 g. These results indicate that calculating NPS per serving size allows for the assessment of the nutritional value of food items in accordance with actual consumption quantities. Therefore, the Meiji NPS calculated per serving size, alongside the per 100 g version, may be useful for dietary management depending on specific purposes.

19 June 2025 in Human Nutrition & Metabolism
Verified
Journal Article
Open access
TYTao Yu
Tao Yu
SZShu Zhang
Shu Zhang
Ryota WakayamaRyota Wakayama
Ryota Wakayama
THTomohito Horimoto
Tomohito Horimoto
CTChikako Tange
Chikako Tange
RORei Otsuka
Rei Otsuka

30 April 2026 in Applied Sciences
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Journal Article
Open access
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Akihito NAKANISHIAkihito NAKANISHI
Akihito NAKANISHI
ZMZaiken Mito
Zaiken Mito
THTomohito Horimoto
Tomohito Horimoto
Bioplastics are increasingly expected to function not only as alternatives to fossil-derived plastics but also as components of circular plastic systems. However, currently bioplastics remain limited by cost, feedstock availability, achievable biomass content, and end-of-life compatibility. This review examines these limitations by organizing recent technological and policy trends in bioplastics, with particular attention to Japan’s social and industrial infrastructure. On this basis, we discuss a systems-level framework for circular plastics that integrates regionally underutilized non-edible biomass, decentralized production concepts, and the emerging possibility of cell-plastics based on unicellular green algae. We argue that the practical dissemination of biomass plastics requires not only material development but also compatibility with molding processes, recycling and biodegradation pathways, and regional collection and treatment systems. In this context, cell-plastics derived from Chlamydomonas reinhardtii are positioned as an emerging technological platform for direct biomass utilization and interfacial material design, although their large-scale implementation remains limited by current cultivation and manufacturing constraints. We propose that circular biomass-plastics systems in Japan should be developed as regionally adapted production frameworks with clearly defined end-of-life pathways, rather than as simple substitutes for petroleum-derived plastics.

31 March 2024 in Microorganisms
Verified
Journal Article
Open access
PDF file
Akihito NAKANISHIAkihito NAKANISHI
Akihito NAKANISHI
Misaki YOMOGITAMisaki YOMOGITA
Misaki YOMOGITA
THTomohito Horimoto
Tomohito Horimoto
Utilities of whey powder (WP) and whey protein concentrate 34% powder (WPC34) prepared as dairy-processing residues were evaluated using a green alga Chlamydomonas reinhardtii. Analysis of C. reinhardtii growth showed that the strain used WP and WPC34 as nitrogen sources. Its specific growth rate and maximum cell density in WP-containing medium were higher than those in WPC34-containing medium; growth with WPC34 was improved by adding KCl or K2HPO4, which content was decreased as a result of WPC34’s preparation from WP. Although the lipid contents in media containing dairy-processing residues were 2.72 ± 0.31 wt% and 2.62 ± 0.20 wt% with no significant difference, the composition ratio of fatty acid C14 with WPC34 was higher than that with WP and the composition ratio of the sum of fatty acid-C16 and -C18 with WPC34 tended to be lower than that with WP. Additionally, analyses of gene transcription showed that the transcription level of acetyl-CoA carboxylase biotin carboxyl carrier protein in WPC34-containing medium was lower than that in WP-containing medium, possibly affecting the ratios of the chain lengths of fatty acids. The transcription of genes involved in glycolysis and the TCA cycle was outstandingly lower in algae grown in WPC34-containing medium when compared to those cultivated in the presence of WP, resulting in differences in energy production for cell proliferation.