Nunzio Denora

Prof. Nunzio Denora

Department of Pharmacy - Pharmaceutical Sciences, University of Bari “Aldo Moro”, Bari, Italy;
orcid

Research Focus & Metrics

Academic Career Length

23Years (2004-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 February 2021 in Journal of Controlled Release
Verified
Journal Article
Open access
SSSimona Summonte
Simona Summonte
Giuseppe Francesco RacanielloGiuseppe Francesco Racaniello
Giuseppe Francesco Racaniello
ALAngela Lopedota
Angela Lopedota
Nunzio DenoraNunzio Denora
Nunzio Denora
ABAndreas Bernkop-Schnürch
Andreas Bernkop-Schnürch
This review focuses on the synthesis of hydrogel networks using thiomers such as thiolated hyaluronic acid, chitosan, cyclodextrin, poly(ethylene glycol) and dextran that are cross-linked via their thiol substructures. Thiomers have been widely investigated as matrix of hydrogels due to the high reactivity of these sulfhydryl moieties. They are well known for their in situ gelling properties due to the formation of inter- and intra-chain disulfide bonds. Furthermore, as thiol groups on the polymeric backbone of thiomers cannot only react with each other but also with different other functional groups, several "click" methods such as thiol-ene/yne, Michael type addition and thiol-epoxy reactions have been developed within the last decades to fabricate thiomer hydrogels. These hydrogels are meanwhile used as scaffolds for tissue engineering, regenerative medicine, diagnostics and as matrix for drug and protein delivery.

1 October 2011 in International Journal of Pharmaceutics
Verified
Journal Article
Closed access
ATAdriana Trapani
Adriana Trapani
Elvira De GiglioElvira De Giglio
Elvira De Giglio
DCDamiana Cafagna
Damiana Cafagna
Nunzio DenoraNunzio Denora
Nunzio Denora
Gennaro AgrimiGennaro Agrimi
Gennaro Agrimi
GTGiuseppe Trapani
Giuseppe Trapani

10 August 2009 in Expert Opinion on Drug Delivery
Verified
Journal Article
Closed access
VLValentino Laquintana
Valentino Laquintana
ATAdriana Trapani
Adriana Trapani
Nunzio DenoraNunzio Denora
Nunzio Denora
FWFan Wang
Fan Wang
JGJames M Gallo
James M Gallo
GTGiuseppe Trapani
Giuseppe Trapani
Background: Malignant brain tumors are among the most challenging to treat and at present there are no uniformly successful treatment strategies. Standard treatment regimens consist of maximal surg...

1 February 2021 in Acta Biomaterialia
Verified
Journal Article
Closed access
IAIlaria Arduino
Ilaria Arduino
ZLZehua Liu
Zehua Liu
ARAntti Rahikkala
Antti Rahikkala
PFPatrícia Figueiredo
Patrícia Figueiredo
ACAlexandra Correia
Alexandra Correia
Hélder SantosHélder Santos
Hélder Santos

1 August 2020 in Journal of Pharmaceutical Sciences
Verified
Journal Article
Closed access
Antonio LopalcoAntonio Lopalco
Antonio Lopalco
ALAngela A. Lopedota
Angela A. Lopedota
VLValentino Laquintana
Valentino Laquintana
Nunzio DenoraNunzio Denora
Nunzio Denora
VSValentino J. Stella
Valentino J. Stella

9 July 2015 in Journal of Medicinal Chemistry
Verified
Journal Article
Closed access
RFRoberta Farina
Roberta Farina
Leonardo PisaniLeonardo Pisani
Leonardo Pisani
MCMarco Catto
Marco Catto
Orazio NicolottiOrazio Nicolotti
Orazio Nicolotti
DGDomenico Gadaleta
Domenico Gadaleta
ACAngelo Carotti
Angelo Carotti