Khalid Alzahrani

Dr. Khalid Alzahrani

orcid

Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 November 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
RSramy samargandi
ramy samargandi
MKMuhand AL KAMESHKI
Muhand AL KAMESHKI
MBMohammad Barnawi
Mohammad Barnawi
KAKhalid Alzahrani
Khalid Alzahrani
OIOthman Iskander
Othman Iskander
LNLouis-Romée Le Nail
Louis-Romée Le Nail
Background: Percutaneous treatment for primary aneurysmal bone cysts (ABCs) has been widely accepted. The study aimed to evaluate the efficacy of various sclerotherapy agents on patients with primary ABCs. Methods: A meta-analysis of relevant studies. A systematic search was conducted on five databases, resulting in the inclusion of 25 studies with different percutaneous agents. Results: A total of 729 patients with primary ABCs were included. Patients were administered with Ethibloc, doxycycline, embolization, alcohol, polidocanol, and calcitonin with methylprednisolone, respectively. Overall, 542 (74.3%) patients with ABCs had complete healing, 120 (16.4%) had partial healing, 44 (6%) had no-ossification or failure, and 26 (3.5%) had a recurrence. However, there was a total of 45 (6.1%) patients who had surgical curettage after sclerotherapy. Among the sclerotherapy agents, doxycycline showed highly effective results with minimal complications and recurrence, but it required multiple injections per patient. Ethibloc and embolization also proved to be highly effective with fewer injections required but had a higher rate of complications. Absolute alcohol, polidocanol, and calcitonin with methylprednisolone had similar efficacity and favorable success with fewer complications and fewer injections. Conclusion: Percutaneous treatment showed promising results in treating primary ABCs. However, more robust research is needed to establish the best approach for sclerotherapy in clinical practice and to address the limitations of the current literature.

10 October 2024 in Journal of Pediatric Surgery
Verified
Journal Article
Closed access
LHLymeymey Heng
Lymeymey Heng
KAKhalid Alzahrani
Khalid Alzahrani
LMLouise Montalva
Louise Montalva
GPGuillaume Podevin
Guillaume Podevin
FSFrançoise Schmitt
Françoise Schmitt
LDLoren Deslandes
Loren Deslandes

18 February 2025 in European Journal of Pediatric Surgery
Verified
Journal Article
Closed access
PDF file
KAKhalid Alzahrani
Khalid Alzahrani
LHLymeymey Heng
Lymeymey Heng
NKNaziha Khen-Dunlop
Naziha Khen-Dunlop
NPNicoleta Panait
Nicoleta Panait
EHErik Hervieux
Erik Hervieux
FSFrançoise Schmitt
Françoise Schmitt
This study compares various surgical approaches for treating congenital diaphragmatic eventration (CDE) in children to identify the most effective and safest method.We conducted a retrospective analysis of a multicentric cohort of pediatric patients operated on for CDE between 2010 and 2021. The different surgical approaches, including robot-assisted thoracoscopic surgery (RATS), and their outcomes were compared (Clinical Trials NCT04862494).One hundred and twelve patients, aged 12 (5–21) months, underwent diaphragmatic plication. Thoracoscopy or RATS was performed in 69 (62%) cases, posterolateral thoracotomy (PLT) in 15 (13%), and an abdominal approach in 28 (25%), based on surgeons' choice. Symptom relief was achieved in 88% of patients, and 90% showed radiographic improvement. There were 31 peri- or early postoperative complications (28%), mainly including pleural effusions, infections, and lobar atelectasis, and 8 recurrences of eventration (7%), with no significant correlation between these complications and the surgical approach. Compared to other approaches, thoracotomy multiplied the duration of intravenous analgesia by three (96 h vs. 36 h, p < 0.0001) and hospital stay length by two (8 vs. 4 days, p = 0.002). RATS, although comparable to thoracoscopy in short-term outcomes, had a higher incidence of perioperative hepatic injuries and long-term complications, including persistent symptoms in all five patients and chest wall deformities in two.Diaphragmatic plication via a minimally invasive thoracic approach may be the best treatment option for cases of symptomatic CDE. Further research is required to establish potential added risks of RATS as compared to thoracoscopy in this indication.

29 November 2024 in Medicine
Verified
Journal Article
Open access
MBMohammad Barnawi
Mohammad Barnawi
DADuaa Alawadi
Duaa Alawadi
KAKhalid Alzahrani
Khalid Alzahrani
RSramy samargandi
ramy samargandi
MBMariam Boutros
Mariam Boutros
It is a common preconception in France that anesthesiologists consume the largest amounts of coffee. This study is aimed to evaluate the relation between working in anesthesiology and increased coffee consumption. Cross-sectional, multicentric study carried out on anesthesiology professionals in France including anesthesiologists (residents and seniors) and Certified Registered Nurse Anesthetists (nurses and students). We performed a paper-based and a web-based survey among participants in the period from January 31, 2020, until March 31, 2020. Data were recorded for each participant including, demographics, function, place of work, and details of coffee consumption. Coffee consumption. We considered the hypothesis to be statistically significant if P < .01. F test was performed to evaluate the variance between different populations. A total of 690 anesthesiology professionals participated in this survey. Average caffeine consumption within anesthesiology team is 308 ± 168 mg/d in the daily operating room and 359 ± 200 in on-call duties. The is a statistically significant increase in caffeine consumption during work in anesthesiology (P < .001). Evolution of coffee consumption were more important in daily operating room than in on-call duties with F test of 118.54 and 205.14, respectively. The majority of respondents (74%) enjoyed coffee for pleasure, while 12% drank it to boost alertness. However, 71% noticed no improvement in attention after consumption. Caffeine dependence symptoms were seen in only 5% of all respondents and 11% of those who consumed 600 mg or more of caffeine daily. Working in the field of anesthesiology seems to be associated with increased coffee consumption, however average coffee consumption among anesthesiologist in France is considered safe. These findings underscore the importance of carefully managing working conditions, shift schedules, and working hours for anesthesiologists to lessen potential risks associated with excessive caffeine intake.

10 June 2024 in Cureus
Verified
Journal Article
Open access
PDF file
KAKhalid Alzahrani
Khalid Alzahrani
KAKhalid Alzahrani
Khalid Alzahrani
SASara M. Alghamdi
Sara M. Alghamdi
HAHamdah A. Alshamrani
Hamdah A. Alshamrani
HAHaneen A. Alghamdi
Haneen A. Alghamdi
MBMohammad I. Barnawi
Mohammad I. Barnawi
Background: Instances of choking continue to pose a concern for the health and safety of children. This study aims to assess parents' understanding, awareness, and perspectives on child choking. Methods: A cross-sectional study was conducted in the Al-Baha region of Saudi Arabia from September 13, 2023, to October 3, 2023. Data collection was done via an electronically validated questionnaire among parents aged 18 years and above, covering knowledge, attitudes, and practices. Statistical analysis was performed using the Mann-Whitney U test, the Kruskal-Wallis test, the Shapiro-Wilk test, and the Kolmogorov-Smirnov test. Any result below 0.05 (p < 0.05) was considered significant. Results: Out of 819 participants, 705 individuals were included in the analysis. The results indicated that there was a good level of knowledge (55%) regarding handling child choking situations. Interestingly, females demonstrated higher levels of awareness compared to males (79.4% versus 20.6%). Attitudes toward managing child choking incidents were rated as overall moderate, with 66.5% showing poor practices, such as being hesitant to seek medical assistance if symptoms improved. A majority of choking cases occurred at home (85%), underscoring the importance of enhancing intervention strategies through increased knowledge dissemination. Notably, the internet and social media platforms (71.8%) emerged as primary sources of information on dealing with child choking incidents. There was significant interest in cardiopulmonary resuscitation (CPR) classes (69.2%), although many people found it hard to make time for them (45%). Conclusions: Parents in the Al-Baha area seem to have a good understanding but some concerning attitudes when it comes to child choking situations. It is important to spread awareness, correct misconceptions, and encourage CPR training.

1 July 2025 in Translational Pediatrics
Verified
Journal Article
Open access
PDF file
KAKhalid Alzahrani
Khalid Alzahrani
Background and Objective: Fournier gangrene (FG) is an uncommon, severe condition characterized by the onset of severe tissue infection in the perineal area, with significant implications for the pediatric population. The current review has been drafted to shed light on the various aspects of pediatric FG, including its etiology, risk factors, clinical presentation, diagnostic approach, management strategies, and outcomes. Methods: A comprehensive review of pediatric FG was conducted on the existing data on its strategies, clinical features, complications, treatments, and outcomes. A detailed literature search was done on databases using PubMed, Scopus, and Web of Science with keywords such as “Fournier gangrene”, “Pediatric Fournier gangrene”, “Fournier gangrene in children”, and “necrotizing soft tissue infections (NSTI)”. Due to the limited pediatric data, adult FG data were used to explain the diagnostic scoring system, treatment strategies. Key Content and Findings: The review highlights the prevalence of FG in pediatric populations and reinforces the requirement for early diagnosis with prompt medical intervention to manage pediatric FG. The etiology and pathophysiology of pediatric FG are also discussed, along with the underlying causes and specific risk factors such as existing congenital abnormalities of the genitourinary and gastrointestinal systems. The management of pediatric FG requires the implementation of a multidisciplinary approach, which should begin with immediate clinical intervention, proper surgical procedures, implementation of pharmacological therapies, and antibiotic regimens to avoid potential complications. Preventive strategies should focus on public health education, hygiene, and vaccination to boost immunity and prevent pediatric FG. The current review suggests future directions to ameliorate clinical practices and achieve favourable outcomes in managing pediatric FG. Conclusions: FG, despite its rare occurrence in the pediatric population, poses a humongous challenge to the healthcare community owing to its rapid onset, complex diagnosis, and high morbidity and mortality rates. Early diagnosis, combined with prompt medical and surgical intervention, with a coordinated multidisciplinary approach, is essential in the management of FG in children. The review provides a glimpse of the shortcomings of the healthcare system and emphasizes the need to improve treatment protocols while also evaluating the long-term impacts of the disease.