Background: Percutaneous treatment for primary aneurysmal bone cysts (ABCs) has been widely accepted. The study aimed to evaluate the efficacy of various sclerotherapy agents on patients with primary ABCs. Methods: A meta-analysis of relevant studies. A systematic search was conducted on five databases, resulting in the inclusion of 25 studies with different percutaneous agents. Results: A total of 729 patients with primary ABCs were included. Patients were administered with Ethibloc, doxycycline, embolization, alcohol, polidocanol, and calcitonin with methylprednisolone, respectively. Overall, 542 (74.3%) patients with ABCs had complete healing, 120 (16.4%) had partial healing, 44 (6%) had no-ossification or failure, and 26 (3.5%) had a recurrence. However, there was a total of 45 (6.1%) patients who had surgical curettage after sclerotherapy. Among the sclerotherapy agents, doxycycline showed highly effective results with minimal complications and recurrence, but it required multiple injections per patient. Ethibloc and embolization also proved to be highly effective with fewer injections required but had a higher rate of complications. Absolute alcohol, polidocanol, and calcitonin with methylprednisolone had similar efficacity and favorable success with fewer complications and fewer injections. Conclusion: Percutaneous treatment showed promising results in treating primary ABCs. However, more robust research is needed to establish the best approach for sclerotherapy in clinical practice and to address the limitations of the current literature.

It is a common preconception in France that anesthesiologists consume the largest amounts of coffee. This study is aimed to evaluate the relation between working in anesthesiology and increased coffee consumption. Cross-sectional, multicentric study carried out on anesthesiology professionals in France including anesthesiologists (residents and seniors) and Certified Registered Nurse Anesthetists (nurses and students). We performed a paper-based and a web-based survey among participants in the period from January 31, 2020, until March 31, 2020. Data were recorded for each participant including, demographics, function, place of work, and details of coffee consumption. Coffee consumption. We considered the hypothesis to be statistically significant if P < .01. F test was performed to evaluate the variance between different populations. A total of 690 anesthesiology professionals participated in this survey. Average caffeine consumption within anesthesiology team is 308 ± 168 mg/d in the daily operating room and 359 ± 200 in on-call duties. The is a statistically significant increase in caffeine consumption during work in anesthesiology (P < .001). Evolution of coffee consumption were more important in daily operating room than in on-call duties with F test of 118.54 and 205.14, respectively. The majority of respondents (74%) enjoyed coffee for pleasure, while 12% drank it to boost alertness. However, 71% noticed no improvement in attention after consumption. Caffeine dependence symptoms were seen in only 5% of all respondents and 11% of those who consumed 600 mg or more of caffeine daily. Working in the field of anesthesiology seems to be associated with increased coffee consumption, however average coffee consumption among anesthesiologist in France is considered safe. These findings underscore the importance of carefully managing working conditions, shift schedules, and working hours for anesthesiologists to lessen potential risks associated with excessive caffeine intake.

Nefopam is a safe analgesic with mild side effects including drowsiness, nausea, vomiting, and sweating. Nevertheless, research is scarce on the impact of nefopam in managing postoperative pain following laparoscopic cholecystectomy (LC), and the advantageous effects of nefopam remain unclear. In this research, the effectiveness of nefopam was compared to placebo for the treatment of postoperative pain following LC. A literature search for randomized controlled trials (RCTs) was performed through June 2024 using online databases including Cochrane Library, PubMed/Medline, and Web of Science. The primary outcome assessed was the quality of postoperative patient pain, and the secondary outcome was side effects that occurred due to the use of nefopam. The Cochrane Risk of Bias (RoB) 2 tool was used to assess the RoB. The meta-analysis was conducted using Review Manager software version 5.4. The risk ratio (RR), mean difference (MD), and standardized mean difference (SMD) were calculated at 95% confidence intervals (CIs). Five RCTs comprising 254 participants were analyzed. The analysis revealed that compared to placebo, nefopam had no statistically significant effect on the reduction of postoperative pain severity at 30 min (SMD = −0.30, 95% CI: −0.61 to 0.01; P = 0.06) and 60 min (SMD = −0.31, 95% CI: −0.78 to 0.16; P = 0.20). Nefopam reduced the number of opioids taken, as shown in the meta-analysis (SMD = −0.94, 95 CI: −1.35 to −0.53; P < 00001), with minor heterogeneity (P = 0.24, I² = 30%). This meta-analysis showed that nefopam lengthened the time to first rescue analgesia (MD = 23.003). and markedly reduced the number patients requiring analgesics compared to baseline (RR = 0.34, 95% CI: 0.22 to 0.54; P < 0.00001). Nefopam did not cause any difference in total postoperative pain but was effective in reducing overall opioid consumption and the need for supplementary analgesics. It did not increase postoperative nausea and vomiting.

Context: Cardiopulmonary resuscitation (CPR) is a crucial lifesaving technique in cases of cardiac arrest and should be performed by any member of the community. Aims: To investigate the level of knowledge regarding CPR among the general population in the Al-Baha region, Saudi Arabia. Settings and Design: A cross-sectional study was conducted in Al-Baha from July 1, 2023 to August 1, 2023. Methods and Material: Inclusion criteria were individuals aged 18 and above living in Al-Baha who consented to participate. Exclusion criteria included individuals under 18 years old, healthcare professionals, residents outside Al-Baha, individuals who refused to participate, and incomplete questionnaires. Data was collected using an anonymous self-administered validated electronic questionnaire in Arabic distributed through social media. Statistical Analysis Used: The Mann–Whitney U test, the Kruskal–Wallis test, the Shapiro–Wilk test, and the Kolmogorov–Smirnov test. Any result below 0.05 (P < 0.05) was considered significant. Results: A total of 852 were included, with 65.0% of respondents female, the largest age group was 18–30 years old (43.9%). A total of 77.5% had sufficient CPR knowledge, with an average score of 11.2 out of 18. While many knew key CPR practices, gaps in knowledge existed, such as when to start CPR (15.8%). Challenges included determining unresponsiveness (26.8%) and fear of causing harm (73.6%). Social media apps were the primary source of CPR knowledge (53.8%), but 70.0% were unaware of available CPR courses, despite 75.0% expressing interest in enrolling. Conclusions: Population of Al-Baha showed a good level of knowledge, however, gaps remained need to be targeted during education efforts. The preference for social media and interest in CPR courses highlight opportunities for enhancing public preparedness.

The rise in predatory journals poses a significant risk to academic integrity, particularly for inexperienced researchers. This research aimed to evaluate awareness, knowledge, and perceptions of predatory journals in the western region of Saudi Arabia. This cross-sectional survey was conducted between January and May 2024 using an anonymous, self-administered, online validated questionnaire distributed to medical students in their clinical years in the western region of Saudi Arabia. Data were analyzed using descriptive statistics, and associations between sociodemographic factors and knowledge of predatory journals were assessed utilizing chi-square and Fisher exact tests; all analyses were unadjusted. A total of 405 medical students participated in the study. Most participants (72.6%) regularly participated in faculty-mentored research activities, and over half (51.9%) published research in scientific journals. The primary reason for conducting this research was institution/program requirements (84.7%). Participation in faculty-mentored research and prior publication in scientific journals were strongly associated with predatory journal awareness ( P < .001). Important factors for choosing a journal for publication were indexing in the major database (54.8%), rapid publication (48.9%), and a high journal impact factor (36.0%). Most participants (62.2%) had heard the term “predatory journal,” with common sources being friends/colleagues (34.1%); only 54.3% reported knowing how to identify potentially predatory journals. Medical students in the western region of Saudi Arabia demonstrated moderate awareness of predatory journals, with gaps in knowledge regarding identifying characteristics. These findings underscore the need for targeted educational initiatives, including workshops and mentorship programs, to enhance understanding and promote ethical research practices. Improving awareness of predatory journals is essential for protecting academic integrity and fostering high-quality scientific contributions.

Incorrect use of over-the-counter (OTC) medications in children can result in harmful outcomes. This study aimed to assess parental knowledge and practices regarding OTC medication use in Al-Baha, Saudi Arabia. A cross-sectional study was conducted between January and August 2024 using a validated, self-administered questionnaire distributed via social media. Adults aged 18 years and above residing in the Al-Baha region who consented to participate were included. Data were analyzed using SPSS version 25, with knowledge and practice levels classified based on predefined cutoff scores. Pearson’s chi-squared test was used to examine associations between sociodemographic factors and knowledge or practice levels, with statistical significance set at p < 0.05. A total of 791 participants were included, the majority being female (63.2%) and university graduates (74.7%). While 68.9% demonstrated good knowledge, 88.6% showed poor practice. Higher education was significantly associated with better practice (p = 0.03), and gender was significantly associated with knowledge levels (p = 0.03). Fever was the most commonly identified indication for OTC medication use (81.5%), yet only 15.4% correctly identified the appropriate paracetamol dosage. Healthcare providers were the primary source of drug information for 74.3% of participants. The findings highlight a clear gap between knowledge and practice, underscoring the need for targeted educational interventions. Community-based education, standardized counseling protocols, culturally appropriate materials, digital tools, and online peer support platforms may enhance the safe use of OTC medications. Continuous feedback on educational resources is essential to ensure alignment with current evidence-based guidelines.