Iulia Nastase

Dr. Iulia Nastase


Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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22 January 2025 in Children
Verified
Journal Article
Open access
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PMPETRUTA IULIANA MORARU
PETRUTA IULIANA MORARU
GCGeorgiana Bianca Constantin
Georgiana Bianca Constantin
ODOana Monica Duca
Oana Monica Duca
INIulia Nastase
Iulia Nastase
RMRaul Mihailov
Raul Mihailov
MGMădălin Guliciuc
Mădălin Guliciuc
Background: Cardiac rhythm disorders in children and adolescents have a high incidence. In certain conditions, sudden death may occur. Materials and Methods: We conducted a prospective study including 199 patients divided into two subgroups: one subgroup of 80 practicing different sports and another one of 119 non-sportive, symptomatic patients. We studied all socio-demographic data, medical histories, and the elements revealed by the clinical and paraclinical examinations. Results: Only 39 (19.60%) participants did not practice any kind of sport; 46 participants had cases of sudden cardiac death in their families; 60.80% of children and adolescents were exposed to smoking; among the symptomatic group, symptoms like vertigo, chest pain, lipothymia, and palpitations predominated. Conclusions: A significant percentage of participants with heart rhythm disorders at risk for sudden death was identified. It is extremely important to identify and restrict them from intense physical exertion and to reassess them periodically in order to reduce the risk of sudden cardiac death.

Verified
Journal Article
Open access
PDF file
INIulia Nastase
Iulia Nastase
TITraian Florin Daniel Iordachi
Traian Florin Daniel Iordachi
MGMaria Gurzun
Maria Gurzun
CGCristian Gutu
Cristian Gutu
NSNicolae Sarbu
Nicolae Sarbu
The cardiovascular risk imposed by chronic kidney disease is significantly enhanced, and carotid atherosclerosis is an early indicator of systemic vascular damage. In this review, we summarize available data relative to primary prevention strategies for carotid atherosclerosis in chronic kidney disease (CKD) with a focus on risk-adapted and stage-specific management. We conducted a narrative review of the literature. A structured literature search was performed in major databases (PubMed, Scopus, Web of Science and Google Scholar), focusing on studies published between 2012 and 2025, including observational studies, randomized controlled trials, and international guideline recommendations. The review focuses on blood pressure management, lipid-lowering therapy, glycemic control, antiplatelet therapy, as well as lifestyle interventions and screening strategies in patients with CKD without a history of cerebrovascular events. CKD-specific processes, such as inflammation, endothelial dysfunction and vascular calcification, may influence the progression of carotid plaques, highlighting the need to improve traditional and non-traditional risk factor management. The focus of prevention continues to emphasize blood pressure (BP) and lipid control as well. At the same time, routine carotid screening and systematically implemented antiplatelet therapy have no known benefit, but the potential for elevated bleeding risk, especially in advanced CKD. Primary prevention should therefore focus on optimal medical treatment, as well as disease-specific strategies according to CKD stage. Additional CKD-specific studies with carotid endpoints are necessary.