Adriano Cypriano Faneli

Mr. Adriano Cypriano Faneli

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Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 May 2024 in Clinical Ophthalmology
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JGJaime Guedes
Jaime Guedes
SPSacha Fernandes Pereira
Sacha Fernandes Pereira
Dillan Cunha AmaralDillan Cunha Amaral
Dillan Cunha Amaral
LHLarissa C Hespanhol
Larissa C Hespanhol
AFAdriano Cypriano Faneli
Adriano Cypriano Faneli
BFBruno M Fontes
Bruno M Fontes
Background: Cataract surgery is one of the most frequently performed eye surgeries worldwide, and among several techniques, phacoemulsification has become the standard of care due to its safety and efficiency. We evaluated the advantages and disadvantages of two phacoemulsification techniques: phaco-chop and divide-and-conquer. Methods: PubMed, Cochrane, Embase, and Web of Science databases were queried for randomized controlled trial (RCT), prospective and retrospective studies that compared the phaco-chop technique over the divide-and-conquer technique and reported the outcomes of (1) Endothelial cell count change (ECC); (2) Ultrasound time (UST); (3) Cumulated dissipated energy (CDE); (4) Surgery time; and (5) Phacoemulsification time (PT). Heterogeneity was examined with I2 statistics. A random-effects model was used for outcomes with high heterogeneity. Results: Nine final studies, (6 prospective RCTs and 3 observational), comprising 837 patients undergoing phacoemulsification. 435 (51.9%) underwent the phaco-chop technique, and 405 (48.1%) underwent divide-and-conquer. Overall, the phaco-chop technique was associated with several advantages: a significant difference in ECC change postoperatively (Mean Difference [MD] − 221.67 Cell/mm2; 95% Confidence Interval [CI] − 401.68 to − 41.66; p < 0.02; I2=73%); a shorter UST (MD − 51.16 sec; 95% CI − 99.4 to − 2.79; p = 0.04; I2=98%); reduced CDE (MD − 8.68 units; 95% CI − 12.76 to − 4.60; p < 0.01; I2=84%); a lower PT (MD − 55.09 sec; 95% CI − 99.29 to − 12.90; p = 0.01; I2=100). There were no significant differences in surgery time (MD − 3.86 min; 95% CI − 9.55 to 1.83; p = 0.18; I2=99%). Conclusion: The phaco-chop technique proved to cause fewer hazards to the corneal endothelium, with less delivered intraocular ultrasound energy when compared to the divide-and-conquer technique.

1 March 2024 in Clinical Ophthalmology
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Dillan Cunha AmaralDillan Cunha Amaral
Dillan Cunha Amaral
AMAdriano Henrique Gomes Menezes
Adriano Henrique Gomes Menezes
LLLuan Cavalcante Vilaça Lima
Luan Cavalcante Vilaça Lima
AFAdriano Cypriano Faneli
Adriano Cypriano Faneli
PNPedro Fernandes Souza Neto
Pedro Fernandes Souza Neto
BFBruno Machado Fontes
Bruno Machado Fontes
Introduction: Corneal ectasia leads to progressive irregular corneal curvature and reduced visual acuity. Objective: To assess the safety and effectiveness of corneal collagen cross-linking (CXL) for managing corneal ectasia resulting from refractive laser surgery (RSL). Methods: A systematic review and meta-analysis were realized according to PRISMA guidelines. We searched PubMed, EMBASE, Cochrane, and Web of Science databases for studies on CXL in patients with ectasia after RLS. The outcomes of interest included visual acuity, refractive outcomes, topographic parameters (Kmax, index surface variance (ISV), index of Vertical Asymmetry (IVA), keratoconus index (KI), central keratoconus index (CKI), index of height asymmetry (IHA), index of height decentration (IHD) and Rmin (minimum sagittal curvature)), central corneal thickness, endothelial cell count, and possible adverse events. Statistical analysis was performed using the R software (version 4.2.3, R Foundation for Statistical Computing, Vienna, Austria). Results: 15 studies encompassing 421 patients (512 eyes) were included. The mean age was 32.03 ± 4.4 years. The pooled results showed a stable uncorrected visual acuity post-CXL, with a significant improvement in corrected distance visual acuity (SMD = 0.09; 95% CI: − 0.07 to 0.26). The spherical equivalent decreased significantly (SMD = − 0.09; 95% CI: − 0.35, − 0.02). The topographic parameter Kmax decreased significantly (SMD = 0.15; 95% CI:0.01 to 0.28); however, the other parameters, ISV, IVA, KI, CKI, IHA, IHD, and Rmin, did not change significantly. Central corneal thickness decreased significantly (SMD = 0.24; 95% CI:0.07 to 0.41), and the endothelial cell count remained stable The complications were rare. Conclusion: CXL is a safe and effective technique for managing corneal ectasia after RLS.

9 October 2024 in Revista Brasileira de Oftalmologia
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ANAlexandre Batista da Costa Neto
Alexandre Batista da Costa Neto
JGJaime Guedes
Jaime Guedes
DMDenise J. Mora-Paez
Denise J. Mora-Paez
MFMarcelo Alves Ferreira
Marcelo Alves Ferreira
AFAdriano Cypriano Faneli
Adriano Cypriano Faneli
RARENATO AMBROSIO
RENATO AMBROSIO
Introduction: Myopia is a growing global concern and there is a lack of studies on its prevalence among Brazilian schoolchildren. Methods: This study aimed to determine the prevalence of myopia in Brazilian children aged 3–18 years through a review and meta-analysis of published studies. Eleven high-quality studies were analyzed following the 2022 PRISMA guidelines. Prevalence was calculated using a meta-analysis, considering the heterogeneity among the studies. Results: The overall crude prevalence of myopia in Brazilian children was 7.65%. There [...] ABSTRACT Introduction: Myopia is a growing global concern and there is a lack of studies on its prevalence among Brazilian schoolchildren. Methods: This study aimed to determine the prevalence of myopia in Brazilian children aged 3–18 years through a review and meta-analysis of published studies. Eleven high-quality studies were analyzed following the 2022 PRISMA guidelines. Prevalence was calculated using a meta-analysis, considering the heterogeneity among the studies. Results: The overall crude prevalence of myopia in Brazilian children was 7.65%. There

5 May 2024 in International Ophthalmology
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RORicardo Danilo Chagas Oliveira
Ricardo Danilo Chagas Oliveira
AFAdriano Cypriano Faneli
Adriano Cypriano Faneli
Dillan Cunha AmaralDillan Cunha Amaral
Dillan Cunha Amaral
JCJulia Motta Chagas
Julia Motta Chagas
JGJaime Guedes
Jaime Guedes
LCLuis Claudio Lemos Correia
Luis Claudio Lemos Correia
Purpose: There is limited literature on the ocular manifestations in patients with psoriasis. Therefore, this study aimed to identify the prevalence of and factors associated with ocular manifestations in adults with psoriasis. Methods: This cross-sectional study included Brazilian adults with psoriasis. The dermatological evaluation included diagnosis, clinical form, Psoriasis Area and Severity Index (PASI) measurement, and location of the lesions. Patients underwent a full ophthalmological examination, including the Schirmer I test, Rose Bengala staining, and tear breakup time tests. The results were analyzed using chi-square and Pearson’s linear correlation tests. Results: Of the 130 patients assessed, 118 (90.8%) exhibited ocular abnormalities, with meibomian gland dysfunction (MGD) being the most prevalent (59.2%), followed by dry eye disease (DED) (56.2%). A significant correlation was observed between MGD and PASI (p = 0.05), and between MGD and certain treatment modalities. DED was significantly associated with PASI (p < 0.05). Concurrent use of acitretin was identified as an independent predictor of MGD (odds ratio [OR] = 3.5, p < 0.05), whereas PASI was a protective factor against DED (OR = 0.39, p < 0.01). Conclusion: Given the high prevalence of eye disease among individuals with psoriasis, routine ophthalmological assessments are recommended to prevent possible ocular complications.

8 May 2024 in Vision
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JGJaime Guedes
Jaime Guedes
BFBruno Fernandes
Bruno Fernandes
DMDenisse J. Mora-Paez
Denisse J. Mora-Paez
RBRodrigo Brazuna
Rodrigo Brazuna
ANAlexandre Batista da Costa Neto
Alexandre Batista da Costa Neto
ADAdalmir Morterá Dantas
Adalmir Morterá Dantas
This study aimed to determine the pars plana length in postmortem human eyes using advanced morphometric techniques and correlate demographics to ocular metrics such as age, sex, ethnicity, and axial length. Between February and July 2005, we conducted a cross-sectional observational study on 46 human cadaver eyes deemed unsuitable for transplant by the SBO Eye Bank. The morphometric analysis was performed on projected images using a surgical microscope and a video-microscopy system with a 20.5:1 correction factor. The pars plana length was measured three times per quadrant, with the final value being the mean of these measurements. Of the 46 eyes collected, 9 were unsuitable for the study due to technical constraints in conducting intraocular measurements. Overall, the average axial length was 25.20 mm. The average pars plana length was 3.8 mm in all quadrants, with no measurements below 2.8 mm or above 4.9 mm. There were no statistically significant variations across quadrants or with age, sex, axial length, or laterality. Accurately defining the pars plana dimensions is crucial for safely accessing the posterior segment of the eye and minimizing complications during intraocular procedures, such as intravitreal injections and vitreoretinal surgeries.

17 March 2025 in Journal of Ophthalmic Inflammation and Infection
Verified
Journal Article
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AFAdriano Cypriano Faneli
Adriano Cypriano Faneli
Dillan Cunha AmaralDillan Cunha Amaral
Dillan Cunha Amaral
IMIsabelle Rodrigues Menezes
Isabelle Rodrigues Menezes
GMGuilherme Nunes Marques
Guilherme Nunes Marques
JGJaime Guedes
Jaime Guedes
CMCristina Muccioli
Cristina Muccioli
Purpose: To assess the prevalence of ocular findings in patients with psoriasis and compare the odds of developing these conditions between the psoriatic and control population through a systematic review and meta-analysis. Methods: A comprehensive literature search was conducted using PubMed, Embase, Cochrane, and Web of Science databases to identify studies reporting ocular findings in psoriasis patients. Inclusion criteria encompassed cross-sectional, case-control, cohort studies, case series, and case studies. Data extraction and quality assessment followed PRISMA guidelines. The Newcastle-Ottawa Scale evaluated the risk of bias. Heterogeneity was assessed using Cochran’s Q-test and I² statistics, with a random-effects model applied where significant heterogeneity was present. Results: 30 studies comprising 131,687 patients (13,788 with psoriasis and 117,899 controls) were included. The relative likelihood of ocular findings in psoriasis patients showed to be increased in conjunctival hyperemia (OR = 7.38; 95% CI: 2.47–22.04), conjunctivitis (OR = 4.63; 95% CI: 1.42–15.08), dry eye (OR = 3.47; 95% CI: 2.06–5.83), and meibomian gland dysfunction (OR = 7.13; 95% CI: 2.14–23.72) compared to controls. In contrast, blepharitis, cataracts, episcleritis, glaucoma, pinguecula, pterygium, and uveitis did not differ significantly between the two groups. Conclusions: Psoriasis patients are at increased risk for certain ocular conditions, particularly conjunctival hyperemia, conjunctivitis, dry eye, and meibomian gland dysfunction. Further research is needed to understand the underlying mechanisms and to develop targeted management strategies.