Marise Sabato

Dr. Marise Sabato

orcid

Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 March 2024 in Healthcare
Verified
Journal Article
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Carmela ProtanoCarmela Protano
Carmela Protano
AGAndrea De Giorgi
Andrea De Giorgi
Federica ValerianiFederica Valeriani
Federica Valeriani
EMElisa Mazzeo
Elisa Mazzeo
SZStefano Zanni
Stefano Zanni
Francesca GallèFrancesca Gallè
Francesca Gallè
Digital technologies have greatly developed and impacted several aspects of life, including health and lifestyle. Activity tracking, mobile applications, and devices may also provide messages and goals to motivate adopting healthy behaviors, namely physical activity and dietary changes. This review aimed to assess the effectiveness of digital resources in supporting behavior changes, and thus influencing weight loss, in people with overweight or obesity. A systematic review was conducted according to the PRISMA guidelines. The protocol was registered in PROSPERO (CRD42023403364). Randomized Controlled Trials published from the database’s inception to 8 November 2023 and focused on digital-based technologies aimed at increasing physical activity for the purpose of weight loss, with or without changes in diet, were considered eligible. In total, 1762 studies were retrieved and 31 met the inclusion criteria. Although they differed in the type of technology used and in their design, two-thirds of the studies reported significantly greater weight loss among electronic device users than controls. Many of these studies reported tailored or specialist-guided interventions. The use of digital technologies may be useful to support weight-loss interventions for people with overweight or obesity. Personalized feedback can increase the effectiveness of new technologies in motivating behavior changes.

20 March 2023 in Journal of Hepatology
Verified
Journal Article
Open access
SCSusanna Caminada
Susanna Caminada
AMAnnamaria Mele
Annamaria Mele
LFLuigina Ferrigno
Luigina Ferrigno
VAValeria Alfonsi
Valeria Alfonsi
SCSimonetta Crateri
Simonetta Crateri
MTMaria Elena Tosti
Maria Elena Tosti
Surgical interventions and invasive diagnostic/therapeutic procedures are known routes of transmission of viral hepatitis. Using data from the Italian surveillance system for acute viral hepatitis (SEIEVA), the aim of this study was to investigate the association between specific types of invasive procedures and the risk of acute HBV and HCV infections. Data from SEIEVA (period 2000-2021) were used. The association between acute HBV and HCV infection and potential risk factors, i.e. surgical interventions and diagnostic/therapeutic procedures (given according to the ICD-9-CM classification), was investigated in comparison to age-matched hepatitis A cases, used as controls, by conditional multiple logistic regression analysis. A total of 8,176 cases with acute HBV, 2,179 with acute HCV, and the respective age-matched controls with acute HAV infection were selected for the main analysis. Most of the procedures evaluated were associated with the risk of acquiring HBV or HCV. The strongest associations for HBV infection were: gynaecological surgery (odds ratio [OR] 5.19; 95% CI 1.12-24.05), otorhinolaryngological surgery (OR 3.78; 95% CI 1.76-8.09), and cardiac/thoracic surgery (OR 3.52; 95% CI 1.34-9.23); while for HCV infection, they were: neurosurgery (OR 11.88; 95% CI 2.40-58.85), otorhinolaryngological surgery (OR 11.54; 95% CI 2.55-52.24), and vascular surgery (OR 9.52; 95% CI 3.25-27.87). Hepatitis C was also strongly associated with ophthalmological surgery (OR 8.32; 95% CI 2.24-30.92). Biopsy and/or endoscopic procedures were significantly associated with both HCV (OR 3.84; 95% CI 2.47-5.95) and, to a lesser extent, HBV infection (OR 1.48; 95% CI 1.16-1.90). Despite the progress made in recent years, invasive procedures still represent a significant risk factor for acquiring parenterally transmitted hepatitis viruses, thus explaining the still numerous and unexpected cases diagnosed among the elderly population in Italy. Our results underline the importance of observing universal precautions to control the iatrogenic transmission of hepatitis viruses. Cases of parenterally transmitted acute viral hepatitis in the elderly population, that are difficult to explain based on the most widely recognised risk factors, continue to be diagnosed in Italy. Based on the Italian SEIEVA surveillance of acute viral hepatitis data, this study highlights an increased risk of acquiring hepatitis B and C following exposure to invasive procedures, which might explain the observed cases in elderly individuals. Furthermore, this finding emphasises the need to observe universal precautions strictly, in healthcare settings, including in the case of minor surgical procedures.

29 September 2024 in Urban Science
Verified
Journal Article
Open access
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LPLorenzo Paglione
Lorenzo Paglione
MDMaria Assunta Donato
Maria Assunta Donato
LCLuigi Cofone
Luigi Cofone
MSMarise Sabato
Marise Sabato
Letizia AppolloniLetizia Appolloni
Letizia Appolloni
DDDaniela D'Alessandro
Daniela D'Alessandro
Recently, there has been a growing interest in exploring the relationship between walkability and various aspects such as health, urban planning, and sustainability. This interest stems from the acknowledgement of the impact of walking on issues such as obesity, pollution, and other diseases, even if these are only weakly correlated. This scoping review was carried out to shed light on the link between walkability and health. The main objectives of this review are to describe the tools used to evaluate walkability, to highlight the variations in measurement methods, and to offer a critical evaluation of these tools. The final analysis includes a review of the most recent and comprehensive studies and online resources. Finally, an evaluation of the tools was carried out, with a focus on urban and architectural expertise relating to design, functions, and activities in public spaces, analysing the few available bibliographic references that correlate walkability with measured health outcomes using validated tools and health information flow. Neighbourhood walkability is influenced by the availability of functional amenities, activities, and safety. Failure to consider its importance on human health could lead to urban social inequalities and thus failure to create salutogenic cities, which could have major implications in terms of public health.

30 April 2025 in Sustainability
Verified
Journal Article
Open access
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LCLuigi Cofone
Luigi Cofone
MSMarise Sabato
Marise Sabato
CPCarolina Di Paolo
Carolina Di Paolo
SGStefano Di Giovanni
Stefano Di Giovanni
MDMaria Assunta Donato
Maria Assunta Donato
LPLorenzo Paglione
Lorenzo Paglione
Today, urbanisation and environmental changes are increasingly influencing the social and biological landscape of our planet. This systematic review aims to assess the relationship between urban–architectural and socioeconomic factors and vector concentrations in the urban environment. Following the Preferred Reporting Methodology for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the PubMed, Scopus, and Cochrane libraries were screened for studies conducted in urban contexts and those involving only arboviruses and potential exposure to arboviral vectors in urban environments, published from the beginning to 22 April 2025. Out of a total of 171 identified studies, 132 were selected for further analysis. Of these, 14 studies were eligible. The included studies reported different ways of measuring vector density and different considerations of the urban–architectural or socio-demographic factors related to it. The studies were set in different urban contexts: Asia, Central and South America, Africa and Oceania. Among the vector species, Aedes aegypti was the most analysed, often with Aedes albopictus. Socioeconomic status emerges as a determining factor. Low-income areas experience higher mosquito densities due to overcrowding, sub-optimal infrastructure, and environmental neglect. This review highlights the importance of implementing a standardised and effective global approach in urban health planning.

10 October 2025 in Journal of Respiration
Verified
Journal Article
Open access
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LCLuigi Cofone
Luigi Cofone
MSMarise Sabato
Marise Sabato
CCChiara Colombo
Chiara Colombo
SSStefania Scalingi
Stefania Scalingi
AMAntonio Montesi
Antonio Montesi
FPFederica Patania
Federica Patania
Introduction: Radon is a radioactive noble gas formed from uranium decay in the Earth’s crust. The most significant isotope, 222Rn, emits alpha particles capable of damaging lung tissue and inducing cancer. Radon exposure is affected by geophysical and building characteristics and is recognized as a Group 1 carcinogen by the IARC. Despite regulatory thresholds (e.g., EURATOM standards), health risks remain. Various mitigation methods aim to reduce indoor radon exposure and its impact. Materials and Methods: This systematic review followed PRISMA guidelines. PubMed, Scopus, and Web of Science were searched up to 28 February 2025, using a defined string. Studies with original data on radon exposure and lung cancer risk or mitigation efficacy were included. Independent screening and quality assessment (Newcastle–Ottawa Scale) were conducted by multiple reviewers. Results: Of the 457 studies identified, 14 met the inclusion criteria. Eleven of these investigated the link between indoor radon and lung cancer risk, and three evaluated mitigation strategies. Radon levels were commonly measured using passive alpha track detectors. Levels varied depending on geographical location, season, building design and ventilation, these were higher in rural homes and during the colder months. Case–control studies consistently found an increased lung cancer risk with elevated radon exposure, especially among smokers. Effective mitigation methods included sub-slab depressurisation and balanced ventilation systems, which significantly reduced indoor radon concentrations. Adenocarcinoma was the most common lung cancer subtype in non-smokers, whereas squamous and small cell carcinomas were more prevalent in smokers exposed to radon. Discussion and Conclusions: This review confirms the robust association between indoor radon exposure and lung cancer. Risks persist even below regulatory limits and are amplified by smoking. While mitigation techniques are effective, their application remains uneven across regions. Stronger public education, building codes, and targeted interventions are needed, particularly in high-risk areas. To inform future prevention and policy, further research should seek to clarify radon’s molecular role in lung carcinogenesis, especially among non-smokers.

11 May 2024 in Urban Science
Verified
Journal Article
Open access
PDF file
LCLuigi Cofone
Luigi Cofone
MSMarise Sabato
Marise Sabato
EREnrico Di Rosa
Enrico Di Rosa
CCChiara Colombo
Chiara Colombo
LPLorenzo Paglione
Lorenzo Paglione
Due to major global urbanisation, a careful evaluation of plans (town planning and mobility) and projects (industrial and development) is required in order to measure their impact on health and environmental matrices. In Italy, Legislative Decree No 152/06 introduced two procedures: the EIA (Environmental Impact Assessment) and SIA (Strategic Impact Assessment). Their focus, however, does not consider human health. Recently, the Integrated Environmental and Health Impact Assessment (IEHIA) was introduced; this defines the parameters necessary to provide an EIA that includes human health as a factor. This systematic review was conducted, including both the population impacted by new facilities and the method used to define their impact. Our database search produced 724 articles, of which 33 were eligible. Studies included landfill plans, manufacturing industries, mobility policies, energy production, and the environmental health of an area. All studies show how an approach encompassing multiple parameters can analyse the impact of a new facility in a comprehensive manner. This review shows that the use of health-related environmental impact parameters is essential for the integration of a project into a community, and can allow a wider understanding of the possible impacts on human health, both direct and indirect.