A microwave microfluidic sensor for dielectric characterization of liquids in real time is presented in this paper. The sensor is implemented in microstrip technology and consists of a symmetric splitter/combiner configuration loaded with a pair of identical split ring resonators (SRRs) and microfluidic channels placed on top of them (gap region). The sensor works in differential mode and sensing is based on frequency splitting. Thus, if the structure is unloaded or if it is symmetrically loaded with regard to the axial plane, only one transmission zero (notch) in the frequency response appears. However, if the axial symmetry is disrupted (e.g., by the presence of different liquids in the channels), two transmission zeros arise, and the difference in magnitude (notch depth) and frequency between such transmission zeros is indicative of the difference in the dielectric properties (complex dielectric constant). A circuit schematic, including transmission line sections to describe the distributed components, lumped elements to account for the SRRs and their coupling to the lines and lumped elements to model the liquid properties, is presented and validated. After proper calibration, the functionality of the proposed sensor is demonstrated by measuring the complex permittivity in solutions of deionized water and ethanol as a function of the ethanol content.

Differential permittivity sensors based on a pair of uncoupled microstrip lines, each one loaded with an open complementary split ring resonator (OCSRR), are proposed in this paper. The sensing principle is based on the measurement of the cross-mode insertion loss, very sensitive to asymmetric loading. Thus, by loading one of the OCSRRs with the reference sample, and the other one with the sample under test (SUT), the difference in the complex permittivity between both samples generates an asymmetry that gives rise to mode conversion. From the measurement of the cross-mode transmission coefficient, the dielectric properties of the SUT can be determined, provided those of the reference sample are well known. It is shown that by adding fluidic channels on top of the OCSRRs, the proposed sensor is useful for the measurement of the complex dielectric constant of liquids, and experimental results in mixtures of ethanol and deionized (DI) water and methanol in DI water, as a function of the ethanol/methanol content, are provided. Due to the high sensitivity of the proposed differential sensor to detect small perturbations (asymmetries), the structure is also of interest for the accurate measurement of solute concentrations in liquid solutions. In this paper, the structure is applied to monitor sodium content in aqueous solutions, and it is found that sodium concentrations as small as 0.25 g/L can be resolved.

A differential microwave sensor, based on a pair of uncoupled microstrip lines each one loaded with a split ring resonator (SRR), is applied to the measurement of electrolyte concentration in deionized (DI) water. For that purpose, fluidic channels are added on top of the SRR gaps, the most sensitive parts of the structure. The operating principle is based on the measurement of the cross-mode insertion loss, highly sensitive to small asymmetries caused by differences between the reference liquid and the liquid under test (LUT). In this work, the reference liquid is pure DI water (the solvent), whereas the solution, DI water with electrolyte content, is injected to the LUT channel. The proposed sensor is able to detect electrolyte concentrations as small as 0.25 g/L, with maximum sensitivity of 0.033 (g/L)-1. The sensor is validated by measuring the concentration of three types of electrolytes, i.e., NaCl, KCl and CaCl2. Finally, the sensor is applied to monitor variations of total electrolyte concentration in urine samples.

This paper focuses on the analysis of splitter/ combiner microstrip sections where each branch is loaded with a complementary split ring resonator (CSRR). The distance between CSRRs is high, and hence, their coupling can be neglected. If the structure exhibits perfect symmetry with regard to the axial plane, a single transmission zero (notch) at the fundamental resonance of the CSRR, arises. Conversely, two notches (i.e., frequency splitting) appear if symmetry is disrupted, and their positions are determined not only by the characteristics of the CSRRs but also by the length of the splitter/combiner sections. A model that includes lumped elements (accounting for the CSRR-loaded line sections) and distributed components (corresponding to the transmission lines) is proposed and used to infer the position of the transmission zeros. Frequency splitting is useful for the implementation of differential sensors and comparators based on symmetry disruption. Using the model, the length of the splitter/combiner sections necessary to optimize the sensitivity of the structures as sensing elements is determined. Parameter extraction and comparison with electromagnetic simulations and measurements in several symmetric and asymmetric structures is used to validate the model. Finally, a prototype device sensor/comparator based on the proposed CSRR-loaded splitter/combiner microstrip sections is presented.

In this paper, an analytical method to estimate the complex dielectric constant of liquids is presented. The method is based on the measurement of the transmission coefficient in an embedded microstrip line loaded with a complementary split ring resonator (CSRR), which is etched in the ground plane. From this response, the dielectric constant and loss tangent of the liquid under test (LUT) can be extracted, provided that the CSRR is surrounded by such LUT, and the liquid level extends beyond the region where the electromagnetic fields generated by the CSRR are present. For that purpose, a liquid container acting as a pool is added to the structure. The main advantage of this method, which is validated from the measurement of the complex dielectric constant of olive and castor oil, is that reference samples for calibration are not required.

Microwave sensors based on electrically small planar resonant elements are reviewed in this paper. By virtue of the high sensitivity of such resonators to the properties of their surrounding medium, particularly the dielectric constant and the loss factor, these sensors are of special interest (although not exclusive) for dielectric characterization of solids and liquids, and for the measurement of material composition. Several sensing strategies are presented, with special emphasis on differential-mode sensors. The main advantages and limitations of such techniques are discussed, and several prototype examples are reported, mainly including sensors for measuring the dielectric properties of solids, and sensors based on microfluidics (useful for liquid characterization and liquid composition). The proposed sensors have high potential for application in real scenarios (including industrial processes and characterization of biosamples).