Yi-Yen Tsai

Dr. Yi-Yen Tsai

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 May 2019 in Journal of the Formosan Medical Association
Verified
Journal Article
Open access
YTYi-Yen Tsai
Yi-Yen Tsai
BCBao-Chung Chen
Bao-Chung Chen
YCYu-Ching Chou
Yu-Ching Chou
JLJung-Chun Lin
Jung-Chun Lin
HLHsuan-Hwai Lin
Hsuan-Hwai Lin
THTien-Yu Huang
Tien-Yu Huang
Colonic angiodysplasia (AGD) is a common cause of gastrointestinal bleeding. However, information on the characteristics and prevalence of colonic AGD is limited. We determined the clinical features of and risk factors for active bleeding in colonic AGD in a Taiwanese population. From February 2007 to December 2016, 13,047 patients undergoing 16,760 colonoscopies at the Tri-Service General Hospital were included in this study. Eighty-four patients were diagnosed with AGD. We conducted a retrospective study by analyzing the medical records of these patients. The clinical features and endoscopic findings were evaluated. Furthermore, we distinguished colonic AGD into bleeding and non-bleeding types and identified the risk factors for bleeding in colonic AGD. In our study, the prevalence of colonic AGD was 0.6% among all patients who received colonoscopy. Among patients with colonic AGD, we found that many were aged; in all, 58.3% of patients with colonic AGD were older than 65 years. More than half of the patients had hypertensive cardiovascular disease (53.6%) and the AGD lesions were predominantly located in the left-sided colon (41.7%). We analyzed several factors to identify those associated with bleeding colonic AGD. Our results indicated that age (p < 0.001), hypertension (p = 0.020), atrial fibrillation (p = 0.027), and in-patient status (p = 0.006) were significant factors associated with active bleeding lesions. On multivariate analysis, old age was the only significant risk factor. Angiodysplastic lesions in Taiwanese patients were predominantly identified in the left-sided colon. Old age was an independent risk factor associated with active bleeding in colonic angiodysplasia.

28 June 2021 in Biotechnology and Bioprocess Engineering
Verified
Journal Article
Closed access
PDF file
YTYi-Yen Tsai
Yi-Yen Tsai
CVCarlos I. Vazquez
Carlos I. Vazquez
Ruei-Feng ShiuRuei-Feng Shiu
Ruei-Feng Shiu
AGAshely K. Garcia
Ashely K. Garcia
CLClarence Le
Clarence Le
Wei-Chun ChinWei-Chun Chin
Wei-Chun Chin


25 June 2026 in Archives of orthopaedic and trauma surgery
Verified
Journal Article
Open access
PDF file
YTYi-Yen Tsai
Yi-Yen Tsai
PSPei-Hung Shen
Pei-Hung Shen
CWChia-Chun Wu
Chia-Chun Wu
RPRu-Yu Pan
Ru-Yu Pan
LLLeou-Chyr Lin
Leou-Chyr Lin
JYJui-Jung Yang
Jui-Jung Yang
Introduction The direct anterior approach (DAA) for total hip arthroplasty (THA) has gained increasing adoption in recent years; however, it has been associated with a higher risk of wound-related complications compared with other surgical approaches. Silver-impregnated occlusive dressings have demonstrated antimicrobial potential, though their role in DAA THA remains underexplored. Materials and methods We conducted a retrospective cohort study with a historical control group, reviewing 321 consecutive primary DAA THAs performed by a single surgeon (September 2020–December 2025). Standard sterile gauze was used before August 2021 (n = 76) and a silver-impregnated occlusive dressing (AQUACEL® Ag SURGICAL; ConvaTec, Deeside, UK) thereafter (n = 245). Despite the chronological difference between cohorts, baseline demographic and clinical characteristics did not differ significantly between groups (Table 1). The primary endpoint was acute surgical site infection(SSI) within 30 days (CDC criteria); all patients had ≥ 3 months follow-up to capture early wound-related reoperations as secondary outcomes. Results Four acute SSI events occurred (1.25%). SSI incidence was 3.94% (3/76) with gauze versus 0.41% (1/245) with the silver-impregnated dressing (Fisher’s exact p = 0.043). This corresponds to an absolute risk reduction (ARR) of 3.54% (95% CI, 0.34–10.57) and a number needed to treat (NNT) of 29 (95% CI, 10–293). No deep PJI occurred. Given sparse events, adjusted analyses were considered exploratory; in a penalized (Firth) logistic model, silver dressing remained associated with lower odds of SSI, while higher BMI and diabetes were associated with higher odds. Conclusions In this retrospective historical-control cohort, silver-impregnated occlusive dressing use was associated with a lower 30-day SSI rate after DAA THA. Given the low event rate and potential temporal confounding, these findings should be interpreted cautiously and warrant confirmation in larger studies.