Matti T Laine

Dr. Matti T Laine

orcid

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2017 in Journal of Vascular Surgery
Verified
Journal Article
Closed access
MLMatti T Laine
Matti T Laine
MBMartin Björck
Martin Björck
CBC. Barry Beiles
C. Barry Beiles
ZSZoltán Szeberin
Zoltán Szeberin
ITIan Thomson
Ian Thomson
MVMaarit Venermo
Maarit Venermo

1 April 2016 in European Journal of Vascular and Endovascular Surgery
Verified
Journal Article
Closed access
MLMatti T Laine
Matti T Laine
TVT. Vänttinen
T. Vänttinen
IKI. Kantonen
I. Kantonen
KHK. Halmesmäki
K. Halmesmäki
EWE.M. Weselius
E.M. Weselius
MVM. Venermo
M. Venermo

31 October 2017 in Circulation
Verified
Journal Article
Open access
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MLMatti T Laine
Matti T Laine
SLSani J. Laukontaus
Sani J. Laukontaus
RSReijo Sund
Reijo Sund
PAPekka S. Aho
Pekka S. Aho
IKIlkka Kantonen
Ilkka Kantonen
MVMaarit Venermo
Maarit Venermo
Background—In the event of rupture of an abdominal aortic aneurysm (AAA), mortality is very high. AAA prevalence and incidence of ruptures has been reported to be decreasing. The treatment of AAA has also undergone a change in recent decades with a shift towards endovascular aneurysm repair (EVAR). Our aim was to evaluate how these changes have affected the elective and emergency treatment of AAA and their results in Finland. Methods—All patients treated for AAA in Finland, a country with a population of 5.5 million, during 2000-2014 were searched from the registry of the Finnish Institute for Health and Welfare. Data on all patients who had died due to AAA during the same time period was obtained from Statistics Finland. The data was combined and analyzed. Results—The annual incidence of ruptured AAA was 16.4 per 100 000 population over 50 years and decreased significantly during the study period. Over half of the 4949 patients who suffered a ruptured AAA died outside the hospital. Thirty-day mortality after emergency repair was 39.4%. Intact AAA repair numbered 4956. The absolute number of annual repairs increased during the study period and the use of EVAR became the dominant method of elective repair. Thirty-day mortality in elective AAA repair dropped significantly from 6.3% in 2000-2004 to 2.7% in 2010-2014 mostly due to increase number of EVAR procedures with lower mortality. Long-term mortality in patients treated with EVAR was higher than in patients treated with open repair. Mortality after elective AAA repair was primarily due to cardiovascular causes but there was a slightly higher proportion of AAA-related late deaths in EVAR patients. Conclusions—Ruptured AAA incidence for men over 65 years has declined with nearly 30% in Finland, likely due to decrease in AAA prevalence. The treatment results have improved as well for both elective and emergency repair. Increased use of EVAR has resulted in decrease of mortality after elective AAA repair, but results of open repair have improved as well. However, late mortality from elective EVAR is surprisingly high compared to open repair which may have been exaggerated by patient selection.

10 August 2016 in British Journal of Surgery
Verified
Journal Article
Closed access
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MLMatti T Laine
Matti T Laine
SLS. J. Laukontaus
S. J. Laukontaus
IKI. Kantonen
I. Kantonen
MVM. Venermo
M. Venermo

7 October 2024 in European Heart Journal
Verified
Journal Article
Open access
PDF file
MLMatti T Laine
Matti T Laine
KMKevin Mani
Kevin Mani
KGKim Gunnarsson
Kim Gunnarsson
AWAnders Wanhainen
Anders Wanhainen
RSReijo Sund
Reijo Sund
MVMaarit Venermo
Maarit Venermo
Background and Aims: In 2006, screening of 65-year-old men for abdominal aortic aneurysm (AAA) was started in Sweden. Decline in aneurysm-related mortality has been reported since, but aneurysm incidence has been diminishing globally. Neighbouring Finland with similar population structure and health care system has no AAA screening programme. The aim of this study was to compare incidence and results of AAA repair in Sweden and Finland to differentiate the effect of screening from other changes in the epidemiology and treatment of AAA. Methods: All repairs for intact AAA (iAAA) or ruptured AAA (rAAA) from 1998 to 2017 were identified from national registers, and mortality data for these patients were collected. Results: A total of 15 927 operations for iAAA were performed in Sweden and 6933 in Finland. In Sweden, the yearly operation volume increased after introduction of screening. Both countries showed a decrease in number of rAAA operations, but the decrease was more pronounced in Sweden. Sweden had a higher proportion of all AAA repairs because of rupture in the start of the study but by the end, the proportions were similar in both countries. Long-term survival improved for 65–79-old men in Sweden after start of screening. Conclusions: This study reveals improvements in results of AAA repair in Sweden. A decrease in rAAA repair and increase in iAAA repair were evident after AAA screening was started in 2006 and resulted in better outcomes. These changes are likely the result of AAA screening as they cannot be seen in neighbouring Finland that is lacking an AAA screening programme.

21 August 2023 in European Journal of Vascular and Endovascular Surgery
Verified
Journal Article
Open access
JSJuan Serna Santos
Juan Serna Santos
TKTouko Kaasalainen
Touko Kaasalainen
SLSani Laukontaus
Sani Laukontaus
PBPatrick Björkman
Patrick Björkman
IHIvika Heinola
Ivika Heinola
PAPekka Aho
Pekka Aho
To compare the protective effect of Zero Gravity (ZG) with conventional radiation protection during endovascular aneurysm repair (EVAR). Secondly, user experience was surveyed with a questionnaire on ergonomics. This is a single-centre, prospective, randomised, two-arm trial where 71 consecutive elective infrarenal EVAR procedures were randomised into two groups: (1) operator using ZG and assistant using conventional protection (n = 36), and (2) operator and assistant using conventional radiation protection (n = 35). A movable floor unit ZG system consists of a lead shield (1.0 mm Pb equivalent) for the front of the body and 0.5 mm Pb equivalent acrylic shielding for the head and neck. The ZG also includes arm flaps of 0.5 mm Pb equivalent covering the arm up to the elbow. Deep dose equivalent values, Hp(10) were measured with direct ion storage dosimeters (DIS) placed on various anatomical regions of the operator (axilla, chest, abdomen, and lower leg). Personal dose equivalent values, Hp(3) to eye lenses were measured in the operating and assisting surgeon using thermoluminescence dosimeters. The study was registered at US National Institute of Health #NCT04078165. Protection with the standard protection was superior in chest (0.0 vs. 0.1 μSv), abdomen (0.0 vs. 0.6 μSv), and lower leg (0.4 vs. 2.2 μSv) (p < .001). On the other hand, the ZG system yielded better shielding for the axilla (1.5 vs. 0.0 μSv) and eyes (6.3 vs. 1.1 μSv ) of the operator. The use of ZG hampered the deployment of ancillary shields, which is particularly relevant for protection of the assisting surgeon. Users found ZG more cumbersome than conventional garments, it also impaired communication and reduced field of view. Both ZG and conventional radiation protection reduced radiation exposure. Conventional protection allows better manoeuvrability at the price of wider exposure of the upper arm and axilla. ZG impairs indirectly protection of the assistant.