Niccolo Cenzato

Dr. Niccolo Cenzato

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Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 October 2021 in Dentistry Journal
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NCNiccolo Cenzato
Niccolo Cenzato
ANAnna Nobili
Anna Nobili
Cinzia MasperoCinzia Maspero
Cinzia Maspero
The World Health Organization (WHO) considers malocclusion one of the most important oral health problems, after caries and periodontal disease. Its prevalence is highly variable and is estimated to be between 39% and 93% in children and adolescents. Due to the importance of malocclusions in dentistry, the aim of our review is to assess the frequency of malocclusions among different geographical regions. A literature research was performed through the Pubmed, Medline, Scopus, Web of Science, LILACS, Open Grey and Cochrane Library databases. The “PRISMA” guidelines were used for the following review. Fourteen studies were analysed for this review. Class I was found most frequently, followed by class II and finally class III. Considering the other anomalies, crowding was one of the most frequent with a prevalence of up to 84%, followed by spacing, which reached a frequency of 60%. Prevalence of crossbite and openbite was quite variable, while the evaluation of deepbite revealed more uniform values. The prevalence varied widely for most of the types of malocclusion in relation to the different populations, which suggests a role of genetics and environmental influences, typical of each population in determining dental problems.

26 July 2024 in Applied Sciences
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NCNiccolo Cenzato
Niccolo Cenzato
GIGiada Di Iasio
Giada Di Iasio
CARMEN Martin Carreras-PresasCARMEN Martin Carreras-Presas
CARMEN Martin Carreras-Presas
Alberto CaprioglioAlberto Caprioglio
Alberto Caprioglio
Massimo Del FabbroMassimo Del Fabbro
Massimo Del Fabbro
Introduction: Transparent orthodontic aligners have revolutionized dentistry and orthodontics since the 1990s, offering advantages over traditional fixed appliances in terms of hygiene, comfort, and aesthetics. With the increasing demand for invisible orthodontic treatments, clear aligners have gained popularity, prompting research into materials to enhance their efficacy and performance. Materials and Methods: A scoping review was conducted using electronic databases (Pubmed, Medline, Cochrane Library, Embase, and Scopus) to identify studies on clear aligner materials published in the last decade. Selection criteria focused on studies specific to dental materials, excluding those unrelated to materials or clear aligners. Results: The review included 11 relevant studies evaluating 17 different clear aligner materials. Materials such as polyvinyl chloride derivatives, thermoplastic polyurethanes (TPU), and polyethylene terephthalate glycol (PETG) were commonly used. The studies assessed mechanical, physical, chemical, and optical properties, as well as thermoforming effects, stress decay, and surface characteristics. Discussion and Conclusions: Various materials exhibited distinct properties, with PETG materials offering transparency and flexibility, while TPU-based materials like Smart Track providing durability and elasticity. Thermoforming affected mechanical properties, with both PETG and TPU materials showing decreased efficacy post-thermoforming. Polymer blending improved mechanical properties, but variations existed among different brands and materials. Clear aligner materials exhibit diverse characteristics, influencing their suitability for orthodontic use. PETG-based materials offer transparency and flexibility, while TPU-based materials provide durability and elasticity. However, both materials undergo mechanical changes post-thermoforming, emphasizing the need for further research to optimize material performance for clinical use.

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NCNiccolo Cenzato
Niccolo Cenzato
MFMarco Farronato
Marco Farronato
FTFrancesco Carlo Tartaglia
Francesco Carlo Tartaglia
Lucia GianniniLucia Giannini
Lucia Giannini
Angelo Michele InchingoloAngelo Michele Inchingolo
Angelo Michele Inchingolo
Francesco InchingoloFrancesco Inchingolo
Francesco Inchingolo
Introduction: The study of facial profiles in the dental field is very important for the diagnosis and the dental and orthodontic treatment plan. The aim of this study is to analyze the three-dimensional morphology of the faces of 269 growing patients with Class I and II occlusions, focusing on children aged between 6 and 9 years old. The analysis was conducted using a non-invasive computerized system, which allowed for the automatic collection of facial landmarks and the subsequent reconstruction of three-dimensional coordinates. Materials and methods: The sample comprised 269 children within the specified age range. Each child’s facial features were captured using the non-invasive computerized system, which utilized two infrared CCD cameras, real-time hardware for label recognition, and software for three-dimensional landmark reconstruction. Sixteen cutaneous facial landmarks were automatically collected for each participant. From these landmarks, 10 angular and 15 linear measurements, as well as five direct distance rates, were derived. The mean values for each age class were calculated separately for children with bilateral Angle Class I occlusion and compared with those for children with bilateral Class II occlusion. In all children, the left and right occlusal classes were measured as suggested by Katz. Results: The analysis revealed notable differences, primarily in the three-dimensional angular measurements between children with Class I and II occlusions. Specifically, Class II children exhibited more convex faces in the sagittal plane and a less prominent lower jaw compared to Class I children. However, no significant differences were observed in linear measurements, except for the lower facial height rate, which varied inconsistently across age groups between the two occlusion types. Discussion and Conclusions: the findings of this research highlight distinct three-dimensional facial morphological differences between children with Class I and II occlusions. While Class II children tended to have more convex facial profiles and less prominent lower jaws, linear measurements showed minimal variation between the two occlusion types. These results underscore the importance of three-dimensional analysis in understanding facial morphology in growing patients with different occlusal patterns.

20 July 2024 in British Journal of Oral and Maxillofacial Surgery
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NCNiccolo Cenzato
Niccolo Cenzato
CCCrispino Crispino
Crispino Crispino
ARA. Russillo
A. Russillo
Massimo Del FabbroMassimo Del Fabbro
Massimo Del Fabbro
Gianluca TartagliaGianluca Tartaglia
Gianluca Tartaglia
Joint visco-supplementation is an effective therapeutic approach against the degenerative signs and symptoms of osteoarthrosis/osteoarthritis of the mandibular condyle. Supplements of choice are usually delivered inside the temporomandibular joint (TMJ) by intra-articular infiltration. The present study aimed to assess the clinical effectiveness of pericapsular injection of polinucleotides (PN) and hyaluronic acid (HA). Sixty patients suffering from TMJ osteoarthrosis were recruited and divided into two groups (test group: n = 30, pericapsular injection; control group: n = 30, self-delivered physiotherapeutic exercises). For each patient, maximum opening, right and left lateral excursion, and visual analogue scale (VAS) scores were recorded at four different timepoints by a blinded investigator. Paired Student's t tests were used to compare consecutive measurements of the parameters evaluated within the groups, and unpaired Student's t tests were used for between-group comparisons. All investigated parameters displayed a progressive clinical improvement in both groups, which was more accentuated in the test group. The decrease in VAS score differed significantly between groups (p < 0.0001). Maximum opening showed a continuous increase from baseline (mean (SD) 37.70 (8.33) mm) to T3 (39.68 (7.64) mm), reflecting a progressive improvement, but it was not statistically significant (p = 0.089 at T3 with respect to T0). PN HA pericapsular injection is a minimally invasive treatment that effectively reduces pain and improves mandibular kinematics.

6 February 2023 in Materials
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SKShahnawaz Khijmatgar
Shahnawaz Khijmatgar
Massimo Del FabbroMassimo Del Fabbro
Massimo Del Fabbro
Margherita TumedeiMargherita Tumedei
Margherita Tumedei
TTTiziano Testori
Tiziano Testori
NCNiccolo Cenzato
Niccolo Cenzato
Gianluca TartagliaGianluca Tartaglia
Gianluca Tartaglia
Background. Different factors may affect new bone formation following maxillary sinus floor augmentation for the rehabilitation of posterior edentulous maxilla. The purpose of this study was to determine the influence of residual bone height (RBH) on new bone formation after lateral sinus augmentation utilizing different biomaterials, through a network meta-analysis (NMA). Methods. PUBMED, Scopus, and Web of Science electronic databases were searched until 31 December 2022 to obtain relevant articles. A hand search was also conducted. Randomised controlled studies on maxillary sinus augmentation comparing different grafting materials in patients with atrophic posterior maxilla, in need of prosthetic rehabilitation, were included. The risk of bias was assessed following the guidelines of the Cochrane Collaboration. The primary outcome was new bone formation (NBF), assessed histomorphometrically. The statistical analysis was performed by splitting the data according to RBH (<4 mm and ≥4 mm). Results. A total of 67 studies were eligible for conducting NMA. Overall, in the included studies, 1955 patients were treated and 2405 sinus augmentation procedures were performed. The biomaterials used were grouped into: autogenous bone (Auto), xenografts (XG), allografts (AG), alloplasts (AP), bioactive agents (Bio), hyaluronic acid (HA), and combinations of these. An inconsistency factor (IF) seen in the entire loop of the XG, AP, and Bio+AP was found to be statistically significant. The highest-ranked biomaterials for the <4 mm RBH outcome were XG+AG, XG+AP, and Auto. Similarly, the surface under the cumulative ranking curve (SUCRA) of biomaterials for ≥4 mm RBH was Auto, Bio+XG, and XG+Auto. Conclusion. There is no grafting biomaterial that is consistently performing better than others. The performance of the materials in terms of NBF may depend on the RBH. While choosing a biomaterial, practitioners should consider both patient-specific aspects and sinus clinical characteristics.

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CDClaudia Dolci
Claudia Dolci
NCNiccolo Cenzato
Niccolo Cenzato
Cinzia MasperoCinzia Maspero
Cinzia Maspero
Lucia GianniniLucia Giannini
Lucia Giannini
SKShahnawaz Khijmatgar
Shahnawaz Khijmatgar
FIFrancesco Inchingolo
Francesco Inchingolo
Our study introduces a novel cephalometric analysis aimed at facilitating biomechanical simulations by elucidating the intricate relationship between craniofacial morphology and the size and inclination of the masseter muscle (MM) while incorporating muscle values. Our study analyzes the line of action of the MM drawn between the Gonion (Go) and Orbital (Or) points concerning dental and skeletal references (occlusal and Frankfort planes). A total of 510 pre-treatment lateral cephalometric tracings (217 males, 293 females, aged 6–50 years) and lateral Bolton standard tracings were examined. The key parameters investigated include (a) skeletal-cutaneous class (linear distance between projections of points A′ and B′ on the occlusal plane), (b) the angle between the perpendicular line to the occlusal plane and the Go-Or line at the molar occlusal point, and (c) the angle between the Go-Or line and the Frankfort plane. The assessment of anterior-posterior jaw discrepancy, measured as the skeletal-cutaneous class, ranged from −14.5 to 15.5 mm. Abnormal values were identified in two adolescents, showing no gender- or age-related patterns. The angle between the MM’s line of action (Go-Or) and the normal to the occlusal plane averaged 39.3°, while the angle between Go-Or and Po-Or (Frankfort plane) averaged 41.99°. Age had an impact on these angles, with an average 3° decrease in adults and a 4° increase between ages 6 and 50. A weak relationship was observed between sagittal jaw discrepancy and the angle between Go-Or and the Frankfort plane, with about 20% of the variance explained by the anteroposterior maxillary-mandibular relationship. In conclusion, the study presents a cephalometric analysis of the relationship between craniofacial morphology and masseter muscle parameters. It finds that age influences the angles between key reference points, while the skeletal-cutaneous class does not exhibit age- or gender-specific trends. These findings can contribute to a better understanding of craniofacial biomechanics and aid in clinical orthodontic assessments and treatment planning.