This study aimed to estimate the prevalence of genital, anal and oral HPV infection in Brazil through systematic review and meta-analysis. We searched EMBASE, LILACS, MEDLINE, Web of Science and SciELO from inception to December 2018. Original research articles that assessed the prevalence of genital (i.e., cervical, penile), anal and oral HPV infection in Brazil were selected in pairs by independent authors. No sex, age, HPV vaccination, language or date restrictions were applied. HPV prevalence was estimated and stratified according to risk factors population and by geographic area throughout the country. The study prevalence was pooled using a random effects model. Analysis was performed using R (version 3.5.2), packages meta version 4.9–4 and metaphor 2.0–0. This review is registered on PROSPERO under protocol number CRD42016032751. We identified 3,351 references. After the screening process, 139 of them were eligible for this systematic review (57,513 total participants). Prevalence of cervical HPV was 25.41% (95% CI 22.71–28.32). Additionally, prevalence was 36.21% (95% CI 23.40, 51.33) in the penile region, 25.68% (95%CI 14.64, 41.04) in the anal region, and 11.89% (95%CI 6.26, 21.43) in the oral region. Subgroup analysis showed prevalence in each anatomic site was higher in high-risk populations. The prevalence of HPV is high in the Brazilian population and varies by population risk and anatomic body site, with lower rates in the oral cavity compared to that in the cervical, penile and anal region. Studies on HPV have primarily been developed to evaluate infection and cancer in the cervical region. There is a profound lack of HPV data in many geographic regions of Brazil and for different anatomic sites.

This paper describes an integrated monitoring system designed for individualized environmental risk assessment and management in the workplace. The system incorporates monitoring devices that measure dust, noise, ultraviolet radiation, illuminance, temperature, humidity, and flammable gases. Comprising monitoring devices, a server-based web application for employers, and a mobile application for workers, the system integrates the registration of workers’ health histories, such as common diseases and symptoms related to the monitored agents, and a web-based recommendation system. The recommendation system application uses classifiers to decide the risk/no risk per sensor and crosses this information with fixed rules to define recommendations. The system generates actionable alerts for companies to improve decision-making regarding professional activities and long-term safety planning by analyzing health information through fixed rules and exposure data through machine learning algorithms. As the system must handle sensitive data, data privacy is addressed in communication and data storage. The study provides test results that evaluate the performance of different machine learning models in building an effective recommendation system. Since it was not possible to find public datasets with all the sensor data needed to train artificial intelligence models, it was necessary to build a data generator for this work. By proposing an approach that focuses on individualized environmental risk assessment and management, considering workers’ health histories, this work is expected to contribute to enhancing occupational safety through computational technologies in the Industry 5.0 approach.

This paper presents a monitoring system to measure dust, noise, ultraviolet radiation, illuminance, temperature, and humidity and to check the presence of flammable gases—liquefied petroleum gas (LPG), propane, hydrogen, butane, methane, and carbon monoxide. The system is composed of monitoring devices, a server to process data received from the devices and that runs a web application for employers, and a mobile application for workers to check their exposure data. During employee registration, the health history of the worker concerning common diseases and symptoms related to the monitored agents must be informed. This information is analyzed through a set of predefined rules to generate alerts that the company can consider for planning professional activities to minimize exposure to risk agents. The tests presented in this work are focused on verifying the functionalities of the web interface for employee registration, especially regarding the provision of health information, the updating of this information, and the generation of corresponding alerts. At this stage, fictitious employee information was used. The results showed that the system adequately performs the proposed functionalities, and it was concluded that the solution is viable for testing in a work environment in the future stages of development. The innovative features of this study concern the correlation between workers’ health history and harmful agents to build suggestions and alerts to guide long-term OSH-related decisions.

Introduction Human papillomavirus (HPV) infection is transmitted through skin-to-skin contact, and vaginal and anal sex are the most common transmission routes. Sex workers and men who have sex with men (MSM) are more exposed to the virus, and therefore, a higher frequency of this infection would be expected. The prevalence of HPV infection types and the forms and factors of transmission must be investigated to control infection-related outcomes. This protocol study will be the first nationwide study with a uniform methodology to evaluate HPV prevalence of and infection types among sex workers and MSM in Brazil. Methods and analysis This multicentre cross-sectional study will be conducted with a respondent-driven sampling method to recruit 1174 sex workers and 1198 MSM from all regions of Brazil. The study will consist of preliminary interviews to verify the eligibility criteria and characterise the network size as well as a second questionnaire to obtain sociodemographic, behavioural and sexual information. Specimens from the oral cavity and anal and cervical or penile/scrotal sites will be collected. All HPV samples will be processed in a certified central laboratory. Other sexually transmitted infections will be evaluated by interview and by rapid testing for HIV and syphilis. Strict quality control will be conducted using different procedures, including the training and certification of the health professionals responsible for acquiring data and monitoring visits. Ethics and dissemination The project was approved by the research ethics committee of the main institution and the corresponding ethics committees of the recruitment sites. Due to the literature gap on the sexual health of sex workers and MSM and the intense stigma surrounding these populations, a critical analysis of the study results will contribute to epidemiological knowledge and will be useful for the development of strategies against virus morbidities.