Artificial intelligence (AI) is increasingly applied in a wide range of healthcare and Intensive Care Unit (ICU) areas to serve—among others—as a tool for disease detection and prediction, as well as for healthcare resources’ management. Since sepsis is a high mortality and rapidly developing organ dysfunction disease afflicting millions in ICUs and costing huge amounts to treat, the area can benefit from the use of AI tools for early and informed diagnosis and antibiotic administration. Additionally, resource allocation plays a crucial role when patient flow is increased, and resources are limited. At the same time, sensitive data use raises the need for ethical guidelines and reflective datasets. Additionally, explainable AI is applied to handle AI opaqueness. This study aims to present existing clinical approaches for infection assessment in terms of scoring systems and diagnostic biomarkers, along with their limitations, and an extensive overview of AI applications in healthcare and ICUs in terms of (a) sepsis detection/prediction and sepsis mortality prediction, (b) length of ICU/hospital stay prediction, and (c) ICU admission/hospitalization prediction after Emergency Department admission, each constituting an important factor towards either prompt interventions and improved patient wellbeing or efficient resource management. Challenges of AI applications in ICU are addressed, along with useful recommendations to mitigate them. Explainable AI applications in ICU are described, and their value in validating, and translating predictions in the clinical setting is highlighted. The most important findings and future directions including multimodal data use and Transformer-based models are discussed. The goal is to make research in AI advances in ICU and particularly sepsis prediction more accessible and provide useful directions on future work.

Optimizing path planning for energy efficiency is critical for achieving sustainable vehicular transportation. This paper presents a novel framework for evaluating the impact of path planning algorithms (PPAs) on energy consumption within a simulated environment. We leverage the CARLA simulator to conduct a comparative analysis between the widely used A* and a Hybrid Genetic Algorithm (HGA) across diverse vehicular scenarios. This investigation aims to quantify the influence of PPA selection on vehicle energy expenditure, enabling data-driven optimization for energy minimization. We leverage an offline energy estimation model to further streamline the comparison of the two PPAs. Extensive simulations are employed to demonstrate the efficiency and adaptability of the proposed framework. The findings contribute to the development of energy-efficient path-planning strategies, promoting advancements toward sustainable transportation systems.

The key challenge for future automated driving systems is the need to imitate the intelligence and ability of human drivers, both in terms of driving agility, as well as in their intuitive understanding of the surroundings and dynamics of the vehicle. In this paper a model that utilizes data from different sources coming from vehicular sensor networks is presented. The data is processed in an intelligent manner while integrating knowledge and experience associated with potential and any decision. Moreover, the appropriate directives for the safety of the vehicle as well as alerts in case of upcoming emergencies are provided to the driver. The innovation lies in attributing human-like cognitive capabilities—non-causal reasoning, predictive decision-making, and learning—integrated into the processes for perception and decision-making in safety-critical autonomous use cases. The overall approach is described and formulated, while a heuristic function is proposed for assisting the driver in reaching the appropriate decisions. Comprehensive results from our experiments showcase its efficiency, simplicity, and scalability.