J. Lawrence Marsh

Dr. J. Lawrence Marsh

orcid

Research Focus & Metrics

Academic Career Length

38Years (1989-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 November 2007 in Journal of Orthopaedic Trauma
Verified
Journal Article
Closed access
JMJ. Lawrence Marsh
J. Lawrence Marsh
TSTheddy F. Slongo
Theddy F. Slongo
JAJulie Agel
Julie Agel
JBJ. Scott Broderick
J. Scott Broderick
WCWilliam Creevey
William Creevey
LALaurent Audigé
Laurent Audigé
The purpose of this new classification compendium is to republish the Orthopaedic Trauma Association's (OTA) classification. The OTA classification was originally published in a compendium of the Journal of Orthopaedic Trauma in 1996. It adopted The Comprehensive Classification of the Long Bones developed by Müller and colleagues and classified the remaining bones. In this compendium, the introductory chapter reviews new scientific information about classifying fractures that has been published in the last 11 years. The classification is presented in a revised format that is easier to follow. The OTA and AO classification will now have a unified alpha-numeric code eliminating the differences that have existed between the 2 codes. The code was significantly revised for the clavicle and scapula, foot and hand, and patella. Dislocations have been expanded on an anatomic basis and for most joints will be coded separately. This publication should stimulate new developments and interest in a unified language to code and classify fractures. Further improvements in classification will result in better patient care and clinical research.

1 November 2006 in Journal of Orthopaedic Trauma
Verified
Journal Article
Closed access
TBThomas D Brown
Thomas D Brown
RJRichard C Johnston
Richard C Johnston
CSCharles L Saltzman
Charles L Saltzman
JMJ. Lawrence Marsh
J. Lawrence Marsh
JBJoseph A Buckwalter
Joseph A Buckwalter
Although posttraumatic osteoarthritis (OA) is a common and important entity in orthopedic practice, no data presently exist regarding its prevalence or its relative burden of disease. A population-based estimate was formulated, based on one large institution's experience in terms of its fraction of patients with OA presenting to lower-extremity adult reconstructive clinics with OA of posttraumatic origin. The relative proportion of these patients undergoing total joint replacement provided a basis for extrapolating institutional experience with posttraumatic OA to a populationwide estimate because the numbers of lower-extremity total joint arthroplasty procedures performed were reliably tabulated both within the institution and populationwide. By this methodology, approximately 12% of the overall prevalence of symptomatic OA is attributable to posttraumatic OA of the hip, knee, or ankle. This corresponds to approximately 5.6 million individuals in the United States being affected by posttraumatic OA sufficiently severe to have caused them to present for care by an orthopedic lower-extremity adult reconstructive surgeon. Further, based on the relative prevalence of OA versus rheumatoid arthritis, and their relative impacts as assessed by the SF-36 (Short-Form 36) lower-extremity physical composite scores, about 85.5% of the societal costs of arthritis are attributable to OA. The corresponding aggregate financial burden specifically of posttraumatic OA is Dollars 3.06 billion annually, or approximately 0.15% of the total U.S. health care direct cost outlay.

1 February 2011 in Journal of Orthopaedic Trauma
Verified
Journal Article
Closed access
CHChristopher E Henderson
Christopher E Henderson
LKLori L Kuhl
Lori L Kuhl
DFDaniel C Fitzpatrick
Daniel C Fitzpatrick
JMJ. Lawrence Marsh
J. Lawrence Marsh
Fractures of the distal femur are severe injuries that present many clinical challenges. Nonunion, delayed union, implant failure, and the need for secondary procedures can reflect complications of healing. This article reviews the literature on distal femur fractures treated with locking plates to determine the reported rate of healing difficulties. The PubMed database and the Orthopaedic Trauma Association and American Academy of Orthopedic Surgeons abstract archives were searched for studies including the key words distal femur fracture, supracondylar femur fracture, or locking plate from the year 2000 to the present. Reports were included when distal femur fractures were treated with locking plates and when the number of healed fractures was identified in the study. The reported healing rates and the rate of healing complications were determined from the studies. The time to implant failure was recorded. Those articles that included periprosthetic fractures were separated from those only including acute distal femur fractures. Fifteen full-length publications and three abstracts were included. The rate of complications related to healing ranged from 0% to 32% in these studies. Implant failures occurred late with 75% of the failures occurring after 3 months and 50% occurring after 6 months. Complications of healing including nonunion, delayed union, and implant failure are not infrequent and represent ongoing problems with distal femur fracture treatment. Further clinical research combined with innovation in surgical techniques and implant design will be necessary to improve the results of the last decade.

1 March 2010 in Journal of Orthopaedic Trauma
Verified
Journal Article
Closed access
TLTrevor J Lujan
Trevor J Lujan
CHChris E Henderson
Chris E Henderson
SMSteven M Madey
Steven M Madey
DFDan C Fitzpatrick
Dan C Fitzpatrick
JMJ. Lawrence Marsh
J. Lawrence Marsh
MBMichael Bottlang
Michael Bottlang
Locked plating constructs may be too stiff to reliably promote secondary bone healing. This study used a novel imaging technique to quantify periosteal callus formation of distal femur fractures stabilized with locking plates. It investigated the effects of cortex-to-plate distance, bridging span, and implant material on periosteal callus formation. Retrospective cohort study. One Level I and one Level II trauma center. Sixty-four consecutive patients with distal femur fractures (AO types 32A, 33A-C) stabilized with periarticular locking plates. Osteosynthesis using indirect reduction and bridge plating with periarticular locking plates. Periosteal callus size on lateral and anteroposterior radiographs. Callus size varied from 0 to 650 mm2. Deficient callus (20 mm2 or less) formed in 52%, 47%, and 37% of fractures at 6, 12, and 24 weeks postsurgery, respectively. Callus formation was asymmetric, whereby the medial cortex had on average 64% more callus (P = 0.001) than the anterior or posterior cortices. A longer bridge span correlated minimally with an increased callus size at Week 6 (P = 0.02), but no correlation was found at Weeks 12 and 24 postsurgery. Compared with stainless steel plates, titanium plates had 76%, 71%, and 56% more callus at Week 6 (P = 0.04), Week 12 (P = 0.03), and Week 24 (P = 0.09), respectively. Stabilization of distal femur fractures with periarticular locking plates can cause inconsistent and asymmetric formation of periosteal callus. A larger bridge span only minimally improves callus formation. The more flexible titanium plates enhanced callus formation compared with stainless steel plates.

7 July 2010 in Journal of Bone and Joint Surgery
Verified
Journal Article
Closed access
MBMichael Bottlang
Michael Bottlang
MLMaren Lesser
Maren Lesser
JKJulia Koerber
Julia Koerber
JDJosef Doornink
Josef Doornink
BRBrigitte von Rechenberg
Brigitte von Rechenberg
JMJ. Lawrence Marsh
J. Lawrence Marsh
Background:Locked bridge plating relies on secondary bone healing, which requires interfragmentary motion for callus formation. This study evaluated healing of fractures stabilized with a locked plating construct and a far cortical locking construct, which is a modified locked plating approach that

1 July 2002 in Journal of Bone and Joint Surgery
Verified
Journal Article
Closed access
JMJ. Lawrence Marsh
J. Lawrence Marsh
JBJ. Buckwalter
J. Buckwalter
RGR. Gelberman
R. Gelberman
DDD. Dirschl
D. Dirschl
SOS. Olson
S. Olson
ALA. Llinias
A. Llinias