Jochen Leupold

Dr. Jochen Leupold

orcid

Research Focus & Metrics

Academic Career Length

25Years (2002-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 June 2016 in Magnetic Resonance in Medicine
Verified
Journal Article
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KLKelvin J. Layton
Kelvin J. Layton
SKStefan Kroboth
Stefan Kroboth
FJFeng Jia
Feng Jia
SLSebastian Littin
Sebastian Littin
HYHuijun Yu
Huijun Yu
MZMaxim Zaitsev
Maxim Zaitsev

1 May 2014 in Journal of Magnetic Resonance
Verified
Journal Article
Closed access
MWMatthias C. Wapler
Matthias C. Wapler
JLJochen Leupold
Jochen Leupold
IDIulius Dragonu
Iulius Dragonu
DEDominik von Elverfeld
Dominik von Elverfeld
MZMaxim Zaitsev
Maxim Zaitsev
Ulrike WallrabeUlrike Wallrabe
Ulrike Wallrabe

1 May 2008 in NeuroImage
Verified
Journal Article
Closed access
KZKai Zhong
Kai Zhong
JLJochen Leupold
Jochen Leupold
DEDominik von Elverfeldt
Dominik von Elverfeldt
OSOliver Speck
Oliver Speck

26 July 2012 in NMR in Biomedicine
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Journal Article
Closed access
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JHJan‐Bernd Hövener
Jan‐Bernd Hövener
SBSébastien Bär
Sébastien Bär
JLJochen Leupold
Jochen Leupold
KJKlaus Jenne
Klaus Jenne
DLDieter Leibfritz
Dieter Leibfritz
DEDominik von Elverfeldt
Dominik von Elverfeldt

15 June 2012 in Journal of Magnetic Resonance Imaging
Verified
Journal Article
Open access
PDF file
JHJan‐Bernd Hövener
Jan‐Bernd Hövener
SZStefan Zwick
Stefan Zwick
JLJochen Leupold
Jochen Leupold
AEAnne‐Katrin Eisenbeiβ
Anne‐Katrin Eisenbeiβ
CSChristian Scheifele
Christian Scheifele
ULUte Ludwig
Ute Ludwig
Purpose: To evaluate the ability of conventional and ultra‐short or zero echo time MRI for imaging of soft and solid dental components in and ex vivo.Materials and Methods: Turbo spin echo (TSE), ultra‐short echo time (UTE), and zero echo time (ZTE) MRI were performed on extracted (human and equine) teeth and in vivo using whole‐body and small‐bore MR systems at 3 T, 7T, and 9.4T, respectively.Results: At an isotropic resolution of (600 μm)3, strong signal of soft‐tissue, e.g., mucosa and nerves with excellent contrast was achieved using TSE at 3T in vivo. No signal, though, was obtained from solid components, e.g., teeth (due to short T2). In contrast, dentin, cementum as well as enamel of extracted teeth were readily depicted using UTE and ZTE at a resolution of ≈ (150 μm)3 at 7T and 9.4T. In particular, ZTE provided higher signal in enamel.Conclusion: As an alternative to X‐ray based methods like cone‐beam computed tomography (CT) or conventional CT, the presented results demonstrate the potential of ZTE and UTE MRI as a radiation‐free imaging modality, delivering contrast of soft and solid components at the same time. J. Magn. Reson. Imaging 2012;36:841–846.

16 May 2018 in Journal of Neural Engineering
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Journal Article
Open access
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JEJohannes B Erhardt
Johannes B Erhardt
EFErwin Fuhrer
Erwin Fuhrer
OGOliver G Gruschke
Oliver G Gruschke
JLJochen Leupold
Jochen Leupold
MWMatthias C Wapler
Matthias C Wapler
JKJan Korvink
Jan Korvink
Patients suffering from neuronal degenerative diseases are increasingly being equipped with neural implants to treat symptoms or restore functions and increase their quality of life. Magnetic resonance imaging (MRI) would be the modality of choice for the diagnosis and compulsory postoperative monitoring of such patients. However, interactions between the magnetic resonance (MR) environment and implants pose severe health risks to the patient. Nevertheless, neural implant recipients regularly undergo MRI examinations, and adverse events are rarely reported. However, this should not imply that the procedures are safe. More than 300 000 cochlear implant recipients are excluded from MRI, unless the indication outweighs the excruciating pain. For 75 000 deep brain stimulation (DBS) recipients quite the opposite holds true: MRI is considered an essential part of the implantation procedure and some medical centres deliberately exceed safety regulations, which they refer to as crucially impractical. Permanent MRI-related neurological dysfunctions in DBS recipients have occurred in the past when manufacturer recommendations were exceeded. Within the last few decades, extensive effort has been invested to identify, characterise and quantify the occurring interactions. Yet today we are still far from a satisfying solution concerning a safe and beneficial MR procedure for all implant recipients. To contribute, we intend to raise awareness of the growing concern, summon the community to stop absurdities and instead improve the situation for the increasing number of patients. Therefore, we review implant safety in the MRI literature from an engineering point of view, with a focus on cochlear and DBS implants as success stories of neural implants in clinical practice. We briefly explain fundamental phenomena which can lead to patient harm, and point out breakthroughs and errors made. Then, we end with conclusions and strategies to avoid future implants from being contraindicated in MR examinations. We believe that implant recipients should enter MRI, but before doing so, it should be made sure that the procedure is reasonable.