Digital technologies related to imaging and manufacturing provide the clinician with a wide variety of treatment options. Stereolithography (SLA) offers a simple and predictable way for an accurate reconstruction of congenital or acquired defects. A 65-years old cancer patient with non- keratinized squamous cell carcinoma of left maxillary sinus came for a prosthetic clinical evaluation. A bilateral maxillectomy was performed and the treatment plan included definite obturator prosthesis for the upper arch. CT data and 3D planning software were used to create a 3D printing plastic model of the defect. A wax pattern of the hollow bulb was fabricated and cured with heat-cured silicone soft liner. A final impression was obtained with the hollow bulb placed intraorally. The master cast was duplicated and the new cast was invested and reflasked. The flasks were opened, wax was boiled out and some space was created in the internal part of the obturator. Transparent heat cured acrylic resin was sandwiched with, at the inner part of the bulb, improving the retention between the acrylic denture base and the silicone based soft lining material. The patient was then placed on a 6-month recall. The five-year follow up consists of a chair side relining, when needed, of the definite removable prostheses. Maxillofacial surgery patients may develop postoperative complications such as trismus and pain. In these cases, the combination of digital technology and conventional techniques provide an accurate prosthetic restoration.

Integrating soft components into denture design may significantly enhance the comfort of edentulous patients. Microorganisms, particularly Candida albicans, often colonize soft denture lining materials, which can release metabolic and toxic byproducts linked to the development of Denture-Induced Stomatitis. This study aimed to evaluate the effectiveness of antimicrobial agents incorporated into soft denture liners in inhibiting the adhesion and colonization of C. albicans. A systematic review was conducted through MEDLINE-Pubmed, EMBASE, and the Cochrane Central Register of Controlled Trials. A range of keywords was employed without applying a time filter to identify relevant literature. The review revealed many studies investigating various antimicrobial compounds added to different soft denture liner materials, all demonstrating the ability to inhibit the proliferation of C. albicans. All the antimicrobial agents examined exhibited a significant antifungal effect, with minimal to negligible impact on the physical properties of the denture liners. However, it was noted that the mechanical properties of the liners were modified in direct correlation to the concentration of the antimicrobial agents utilized. The successful incorporation of these agents into various soft denture liners has been documented, with nystatin being the primary pharmacological agent identified across multiple studies. While incorporating antibacterial agents was deemed successful, it is essential to note that the methodologies employed yielded varying effects on the overall performance of the soft-liner materials.

Objectives: CAD-CAM technology has enabled clinicians to provide accurate and predictable restorations. Chairside time has been reduced and patient’s comfort has been improved. A fully digital workflow can be now predictably adopted in implant surgery and implant restorations. Methods: A male patient, 55 years old, was referred for the restoration of his edentulous mandible. Radiographs and clinical evaluation were assembled to plan implant placement. The flapless approach is preferred to provide for a mucosa-supported surgical guide and lessen the patient’s post-operative complications. In flapless cases, the operator does not have any direct overview of the surrounding soft tissues and underlying bone. In this case, a new, minimally invasive H-shaped incision technique was performed. A fully digital protocol is presented with a two-piece stackable surgical guide to confirm accurate implant placement. Results: A high-performance polymer framework (PEEK) combined with zirconia crowns completes the digitally designed edentulous restoration. Conclusions: Adopting this technique offers the clinician benefits in both the surgical and the restorative part.