Objective: To highlight the application of digitally fabricated Snap‐On PMMA provisional restorations as a minimally invasive and adaptable methodology for assessing the vertical dimension of occlusion and occlusal stability during the comprehensive rehabilitation of worn dentition. Clinical Considerations: A clinical case is presented involving a 58‐year‐old male with severe anterior tooth wear, multiple edentulous spaces, and occlusal dysfunction. The patient underwent full‐arch digital rehabilitation through a workflow incorporating intraoral scanning, facial scanning, cone‐beam computed tomography (CBCT), and virtual smile design. Snap‐On PMMA milled provisional restorations enabled real‐time evaluation of the proposed VDO, phonetics, esthetics, and centric occlusion in a reversible, non‐invasive manner. Their use also enabled immediate implant loading at site #22 and facilitated the digital transfer of the validated occlusal scheme from the provisional stage to the definitive CAD/CAM restorations. Definitive restorations were fabricated using monolithic zirconia and lithium disilicate, selected for their superior mechanical strength, longevity, and esthetic potential. Conclusion: Snap‐On PMMA provisional restorations represent an effective diagnostic and transitional tool in the management of worn dentition. Integrated into a fully digital workflow, they enhance treatment predictability by allowing reversible clinical validation and direct digital transfer of occlusal parameters to the final prostheses. Combined with advanced restorative materials, this approach improves treatment predictability, patient satisfaction, and the long‐term clinical success of managing complex cases of worn dentition. Clinical Significance: Snap‐On PMMA provisionals offer a minimally invasive, reversible way to assess occlusion, function, and esthetics before final restoration. This technique enhances accuracy and predictability in full‐mouth rehabilitations, making it highly valuable in esthetic dentistry.

Integrating soft components into denture design may significantly enhance the comfort of edentulous patients. Microorganisms, particularly Candida albicans, often colonize soft denture lining materials, which can release metabolic and toxic byproducts linked to the development of Denture-Induced Stomatitis. This study aimed to evaluate the effectiveness of antimicrobial agents incorporated into soft denture liners in inhibiting the adhesion and colonization of C. albicans. A systematic review was conducted through MEDLINE-Pubmed, EMBASE, and the Cochrane Central Register of Controlled Trials. A range of keywords was employed without applying a time filter to identify relevant literature. The review revealed many studies investigating various antimicrobial compounds added to different soft denture liner materials, all demonstrating the ability to inhibit the proliferation of C. albicans. All the antimicrobial agents examined exhibited a significant antifungal effect, with minimal to negligible impact on the physical properties of the denture liners. However, it was noted that the mechanical properties of the liners were modified in direct correlation to the concentration of the antimicrobial agents utilized. The successful incorporation of these agents into various soft denture liners has been documented, with nystatin being the primary pharmacological agent identified across multiple studies. While incorporating antibacterial agents was deemed successful, it is essential to note that the methodologies employed yielded varying effects on the overall performance of the soft-liner materials.