Se Chul Chun

Prof. Se Chul Chun

Department of Environmental Health Sciences, Konkuk University, Seoul 143-701, Korea
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Research Focus & Metrics

Academic Career Length

23Years (2004-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 September 2020 in Processes
Verified
Journal Article
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Murugesan ChandrasekaranMurugesan Chandrasekaran
Murugesan Chandrasekaran
KKKi Deok Kim
Ki Deok Kim
Se Chul ChunSe Chul Chun
Se Chul Chun
In recent years, nanotechnology has attracted attention in many fields because it has several up-and-coming novel uses. Many researchers have suggested that chitosan nanoparticles (CS-NPs) and their derivatives are one of the best nanomaterials for delivering antibacterial activity. CS-NPs have a broad spectrum of antibacterial activity, but they manifest different inhibitory efficacy against gram-negative (G−) and gram-positive (G+) bacterial species. The mechanism of antibacterial action is an intricate process that varies between G− and G+ bacteria as a result of the differences in cell wall and cell membrane chemistry. In previous studies, greater antibacterial activity was more evident against G− bacteria than G+ bacteria, whereas in some studies G+ bacteria were more sensitive. Researchers predicted that the varied responses of bacteria are caused by the mixed hydrophilicity and negative charge distribution on the bacterial surface. Moreover, its activity depends on a number of variables including bacterial target (i.e., G− or G+ bacteria) and bacterial growth, as well as its concentration, pH, zeta-potential, molecular weight, and degree of acetylation. Therefore, this review examines current research on the mechanisms and factors affecting antibacterial activity, and application of CS-NPs specifically against animal and plant pathogenic bacteria.

8 January 2019 in Agronomy
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Journal Article
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JOJae-Wook Oh
Jae-Wook Oh
Se Chul ChunSe Chul Chun
Se Chul Chun
Murugesan ChandrasekaranMurugesan Chandrasekaran
Murugesan Chandrasekaran
The present study was to prepare chitosan nanoparticles (CNPs) from chitosan (CS) to evaluate their in vitro antimicrobial activities against phytopathogens of tomato. We prepared and characterized CNPs for their particle size, polydispersity index, and structures. The antifungal properties of CS and CNPs against phytopathogenic fungi namely Colletotrichum gelosporidies, Phytophthora capsici, Sclerotinia sclerotiorum, Fusarium oxysporum, Gibberella fujikuori were investigated. CNPs showed the maximum growth inhibitory effects on mycelial growth of F. oxysporum followed by P. capsici. We also studied antibacterial activities against phytopathogenic bacteria, such as three strains of Erwinia carotovora subsp. carotovora and one strain of Xanthomonas campestris pv. vesicatoria. Our results showed that both CS and CNPs markedly inhibited the growth of the both Xanthomonas and Erwinia strains. From our study, it is evident that both CS and CNPs have tremendous potential against phytopathogens of tomato for further field screening towards crop protection.

1 March 2019 in International Journal of Biological Macromolecules
Verified
Journal Article
Closed access
Se Chul ChunSe Chul Chun
Se Chul Chun
Murugesan ChandrasekaranMurugesan Chandrasekaran
Murugesan Chandrasekaran

3 February 2021 in Antioxidants
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Journal Article
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MMManikandan Muthu
Manikandan Muthu
JGJudy Gopal
Judy Gopal
Se Chul ChunSe Chul Chun
Se Chul Chun
ADAnna Jacintha Prameela Devadoss
Anna Jacintha Prameela Devadoss
Nazim HasanNazim Hasan
Nazim Hasan
Iyyakkannu SivanesanIyyakkannu Sivanesan
Iyyakkannu Sivanesan
Chitosan is obtained from chitin that in turn is recovered from marine crustacean wastes. The recovery methods and their varying types and the advantages of the recovery methods are briefly discussed. The bioactive properties of chitosan, which emphasize the unequivocal deliverables contained by this biopolymer, have been concisely presented. The variations of chitosan and its derivatives and their unique properties are discussed. The antioxidant properties of chitosan have been presented and the need for more work targeted towards harnessing the antioxidant property of chitosan has been emphasized. Some portions of the crustacean waste are being converted to chitosan; the possibility that all of the waste can be used for harnessing this versatile multifaceted product chitosan is projected in this review. The future of chitosan recovery from marine crustacean wastes and the need to improve in this area of research, through the inclusion of nanotechnological inputs have been listed under future perspective.

28 January 2016 in Scientific Reports
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Journal Article
Open access
JGJudy Gopal
Judy Gopal
MMManikandan Muthu
Manikandan Muthu
DIBY PAULDIBY PAUL
DIBY PAUL
DKDoo-Hwan Kim
Doo-Hwan Kim
Se Chul ChunSe Chul Chun
Se Chul Chun
When we drink green tea infusion, we believe we are drinking the extract of the green tea leaves. While practically each tea bag infused in 300 mL water contains about 50 mg of suspended green tea leaf particles. What is the role of these particles in the green tea effect is the objective of this study. These particles (three different size ranges) were isolated via varying speed centrifugation and their respective inputs evaluated. Live oral bacterial samples from human volunteers have been screened against green tea extracts and macro, micro and nano sized green tea particles. The results showed that the presence/absence of the macro and mico sized tea particles in the green tea extract did not contribute much. However, the nano sized particles were characterized to be nature’s nano stores of the bioactive catechins. Eradication of these nano tea particles resulted in decrease in the bactericidal property of the green tea extracts. This is a curtain raiser investigation, busting the nano as well as green tea leaf particle contribution in green tea extracts.

26 November 2021 in Antioxidants
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Journal Article
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Se Chul ChunSe Chul Chun
Se Chul Chun
JGJudy Gopal
Judy Gopal
MMManikandan Muthu
Manikandan Muthu
Mushrooms have been long accomplished for their medicinal properties and bioactivity. The ancients benefitted from it, even before they knew that there was more to mushrooms than just the culinary aspect. This review addresses the benefits of mushrooms and specifically dwells on the positive attributes of mushroom polysaccharides. Compared to mushroom research, mushroom polysaccharide-based reports were observed to be significantly less frequent. This review highlights the antioxidant properties and mechanisms as well as consolidates the various antioxidant applications of mushroom polysaccharides. The biological activities of mushroom polysaccharides are also briefly discussed. The antiviral properties of mushrooms and their polysaccharides have been reviewed and presented. The lacunae in implementation of the antiviral benefits into antiCOVID-19 pursuits has been highlighted. The need for expansion and extrapolation of the knowns of mushrooms to extend into the unknown is emphasized.