Ultrasound imaging has become an indispensable diagnostic tool across various medical fields. In recent years, there has been growing interest in the use of ultrasonography for the evaluation of skin lesions. However, scientific reports detailing the precise role of ultrasound in determining the morphology of malignant skin tumors still remain limited. Malignant skin lesions, particularly in the head and neck region—their most common location—pose significant challenges due to the complex anatomy of these areas. The primary treatment for non-melanoma skin cancers, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), is surgical excision. Mohs micrographic surgery is considered the gold standard due to its tissue-sparing approach and high cure rates. However, it is a time-consuming and resource-intensive procedure that is not always widely accessible. In contrast, standard surgical excision, while more widely available, often results in incomplete tumor removal, necessitating subsequent surgical radicalization or the use of adjuvant therapies. Routine ultrasound evaluation of both benign and malignant skin lesions could enhance early detection and facilitate timely treatment. However, the current body of evidence for the usage of skin ultrasound in presurgical evaluation is poor and lacks standardization. Given these challenges, in this review, we aim to highlight the potential value of preoperative skin ultrasonography in accurately assessing benign and malignant skin lesion dimensions and morphology.

Background: Despite advances in treatment, oral squamous cell carcinoma (OSCC) remains associated with high recurrence and mortality rates. Traditional TNM staging, while foundational, may not fully capture tumor aggressiveness. This study aimed to identify clinical and histopathological predictors of survival to enhance risk stratification and guide treatment planning in OSCC patients. Methods: A retrospective study of 100 patients with confirmed OSCC treated surgically with curative intent between January 2019 and January 2024 was analyzed. Clinicopathologic variables—including tumor volume, angioinvasion, perineural invasion, lymphatic invasion, and nodal status—were evaluated. Disease-specific survival (DSS) was assessed using Kaplan–Meier estimates, Cox regression, and logistic regression models. Results: The cohort had a mean age of 62.1 years, with a 46% OS rate and 43% DSS at study end. Perineural invasion (44%) and lymphatic invasion (42%) were the most common invasive features. Kaplan–Meier analysis revealed significantly reduced DSS in patients with angioinvasion, perineural invasion, and pN+ status. Multivariate logistic regression identified perineural invasion (OR = 3.93, p = 0.0023) and pN+ status (OR = 2.74, p = 0.0284) as independent predictors of cancer-specific mortality. Tumor volume was significantly associated with lymphatic invasion but not directly with DSS. Conclusions: Perineural invasion, angioinvasion, lymph node involvement, and tumor volume are important prognostic markers in OSCC, offering critical information beyond TNM staging. Incorporating these features into risk assessment models could improve prognostic accuracy and inform more individualized treatment strategies for high-risk OSCC patients.

The use of 3D printing in the fabrication of immediate prosthetic restorations requires the possibility of sterilization. This study aimed to evaluate the effects of different sterilization methods on the parameters of 3D-printing materials for dental prosthesis plates compared to conventional acrylic material. Forty-four samples were prepared for each tested material: Denture 3D+ (NextDent, The Netherlands), Denturetec (Saremco, Switzerland), Optiprint Laviva (Dentona, Germany), and Rapid Simplified (Vertex Dental, Netherlands). The impact strength of the samples was tested in a HIT 5.5P instrument (Zwick Roell, Germany) after three sterilization methods (pressurized steam, ethylene oxide, and radiation) and without sterilization as a control group. Significantly higher energy and impact strength were recorded for the conventional acrylic material. For Nextdent material, the recommended method of sterilization in terms of impaction is autoclave or ethylene oxide sterilization, Saremco—ethylene oxide sterilization, and Denton—ethylene oxide or radiation sterilization. Conventional acrylic material has a higher impact strength than 3D-printed material, which may encourage the selection of this material for restorations requiring higher fracture strength. The possibility of sterilizing the Nextdent 3D-printed material in the autoclave without worsening its durability makes it a recommended choice for digital clinical practice.