Advancements in camera technology over the past two decades have made image-based monitoring increasingly accessible for healthcare applications. Imaging photoplethysmography (iPPG) and remote photoplethysmography (rPPG) are non-invasive methods for measuring vital signs, such as heart rate, respiratory rate, oxygen saturation, and blood pressure, without physical contact. rPPG utilizes basic cameras to detect physiological changes, while rPPG enables remote monitoring by capturing subtle skin colour variations linked to blood flow. Various rPPG techniques, including colour-based, motion-based, multispectral, and depth-based approaches, enhance accuracy and resilience. These technologies are beneficial not only for healthcare but also for fitness tracking, stress management, and security systems, offering a promising future for contactless physiological monitoring. In this article, there is an overview of these methods and their uniqueness for use in remote photoplethysmography.
This paper presents a technique that can potentially help to determine the receptivity stage of the endometrium from histology images by automatically measuring the stromal nuclear changes. The presented technique is composed of an image segmentation model and the statistical evolution of segmented areas in hematoxylin and eosin (HE)-stained histology images. Three different endometrium receptivity stages, namely pre-receptive, post-receptive, and receptive, were compared. An ensemble-based AI model was proposed for histology image segmentation, which is based on individual UNet++, UNet, and ResNet34-UNet segmentation models. The performance of the ensemble-based technique was assessed using the Dice score and intersection over unit (IoU) values. In comparison to alternative segmentation architectures that were applied singly, the current ensemble-based method obtained higher Dice score (0.95) and IoU (0.90) values. The statistical comparison highlighted a noticeable difference in the number of nuclei and the size of the stroma tissue. The proposed technique demonstrated the positive potential for practical implementation for automatic endometrial tissue analysis.
Assessing human embryo quality is a critical step in in vitro fertilization (IVF), yet traditional manual grading remains subjective and physically limited by the shallow depth-of-field in conventional microscopy. This study develops a novel "soft optical sensor" architecture that transforms standard optical microscopy into an automated, high-precision instrument for embryo quality assessment. The proposed system integrates two key computational innovations: 1) a multi-focal image fusion module that reconstructs lost morphological details from Z-stack focal planes, effectively creating a 3D-aware representation from 2D inputs; and 2) a retrieval-augmented generation (RAG) framework coupled with a Swin Transformer to provide both high-accuracy classification and explainable clinical rationales. Validated on a large-scale clinical dataset of 102,308 images (prior to augmentation), the system achieves a diagnostic accuracy of 94.11%. This performance surpasses standard single-plane analysis methods by over 10%, demonstrating the critical importance of fusing multi-focal data. Furthermore, the RAG module successfully grounds model predictions in standard ESHRE consensus guidelines, generating natural language explanations. The results demonstrate that this soft sensor approach significantly reduces inter-observer variability and offers a viable pathway for fully automated, transparent embryo evaluation in clinical settings.
Assessing human embryo quality is a critical step in in vitro fertilization (IVF), yet traditional manual grading remains subjective and physically limited by the shallow depth-of-field in conventional microscopy. This study develops a novel “soft optical sensor” architecture that transforms standard optical microscopy into an automated, high-precision instrument for embryo quality assessment. The proposed system integrates two key computational innovations: (1) a multi-focal image fusion module that reconstructs lost morphological details from Z-stack focal planes, effectively creating a 3D-aware representation from 2D inputs; and (2) a retrieval-augmented generation (RAG) framework coupled with a Swin Transformer to provide both high-accuracy classification and explainable clinical rationales. Validated on a large-scale clinical dataset of 102,308 images (prior to augmentation), the system achieves a diagnostic accuracy of 94.11%. This performance surpasses standard single-plane analysis methods by 9.43%, demonstrating the critical importance of fusing multi-focal data. Furthermore, the RAG module successfully grounds model predictions in standard ESHRE consensus guidelines, generating natural language explanations. The results demonstrate that this soft sensor approach significantly reduces inter-observer variability and offers a robust tool for standardized morphological assessment, though prospective validation against live birth outcomes remains essential for clinical adoption.