Social desirability is a multicomponent personality trait referring to the tendency of individuals to regulate their answers to establish a positive impression, avoid criticism, or satisfy a need for social approval ( Johnson & Fendrich, 2002 Johnson, T., & Fendrich, M. (2002, May). A validation of the Crowne-Marlowe Social Desirability Scale. Paper presented at the 57th Annual Meeting of the American Association for Public Opinion Research, St. Pete Beach, FL. http://www.srl.uic.edu/publist/Conference/crownemarlowe.pdf (http://www.srl.uic.edu/publist/Conference/crownemarlowe.pdf) [Google Scholar] ; Paulhus, 1984 Paulhus, D. L. 1984. Two-component models of socially desirable responding. Journal of Personality and Social Psychology, 46: 598–609. doi:10.1037/ 0022–3514.46.3.598 [Crossref], [Web of Science ®] [Google Scholar] ). This study investigated the role played by the socially desirable response style assessed with the Marlowe-Crowne Social Desirability Scale ( Crowne & Marlowe, 1960 Crowne, D. P. and Marlowe, D. 1960. A new scale of social desirability independent of psychopathology. Journal of Consulting Psychology, 24: 349–354. doi:10.1037/h0047358 [Crossref], [PubMed] [Google Scholar] ) on self-rated measures of affect (i.e., Center of Epidemiological Studies of Depression Scale; Radloff, 1977 Radloff, L. S. 1977. The CES-D Scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1: 385–401. doi:10.1177/014662167700100306 [Crossref], [Web of Science ®] [Google Scholar] ), metacognitive efficiency (i.e., Sensitivity to Memory Questionnaire; Cornoldi & De Beni, 2003 Cornoldi, C. and De Beni, R. 2003. Leopardisti. Gli amanti della memoria [Leopardists. Memory lovers]. Psicologia Contemporanea, 1: 4–11. [Google Scholar] ; and Cognitive Failures Questionnaire; Borella, Carretti, Cornoldi, & DeBeni, 2007 Borella, E , Carretti, B. , Cornoldi, C. and De Beni, R. 2007. Working memory, control of interference and everyday experience of thoughts interference: A comparison between young, young-old and old-old adults. Aging, Clinical and Experimental Research, 19: 200–206. [Crossref], [PubMed], [Web of Science ®] [Google Scholar] ), and self-perceived psychological wellness (Psychological Wellness and Aging Questionnaire; De Beni, Borella, Carretti, Marigo, & Nava, 2007 De Beni, R. , Borella, E. , Carretti, B. , Marigo, C. and Nava, L. A. 2007. BAC: Benessere e Abilità Cognitive nell'età Adulta e Avanzata. [BAC: Wellness and cognitive abilities in the advanced and adult age], Florence, , Italy: Organizzazioni Speciali. [Google Scholar] ) in a sample composed of young (M = 24.6 years), old (M = 69.4 years), and very old (M = 81.9 years) adults counterbalanced by gender and education (i.e., ≤ 8 years versus > 8 years). Results revealed that social desirability alone predicted measures of affect and emotional competencies and contributed to predicting personal satisfaction, general perceived wellness, and self-rated cognitive efficiency. Overall, the present outcomes suggest clinical psychologists should pay attention to the crucial interference of social desirability in assessing wellness even in late adulthood, that is, in a developmental phase thought to be mainly characterized by reduced control of physical and psychological functions.