Horia-Alexandru Nica

Mr. Horia-Alexandru Nica

orcid

Research Focus & Metrics

Academic Career Length

2Years (2025-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 December 2025 in Life
Verified
Journal Article
Open access
PDF file
IEIrina Anca Eremia
Irina Anca Eremia
Cătălin Alexandru AnghelCătălin Alexandru Anghel
Cătălin Alexandru Anghel
HNHoria-Alexandru Nica
Horia-Alexandru Nica
EEEduard-Alexandru Eremia
Eduard-Alexandru Eremia
Ionut-Lucian Antone-IordacheIonut-Lucian Antone-Iordache
Ionut-Lucian Antone-Iordache
RNRemus Iulian Nica
Remus Iulian Nica
Background and Objectives: Trauma remains a leading global cause of preventable mortality, and outcome prediction tools are essential for both triage and resource allocation. Timely and effective medical response to trauma patients is of the essence. While there are already some widely accepted trauma scores, our aim was to build a more precise model tailored to our cohort as a framework for future research. Materials and Methods: A retrospective cohort of 91 patients was analyzed, using several clinical and paraclinical factors to build a logistic regression model that predicted 30-day mortality. Results: After adjusting for collinearity, our final multiple regression model, comprising systolic blood pressure, glycemia, urea serum levels and number of fractures, showed an excellent model fit (McFadden R2 = 0.682; AUC = 0.94) for predicting 30-day mortality. Systolic blood pressure was significantly associated with mortality (OR = 0.944, 95% CI: 0.920–0.969). In our cohort it seems to surpass the performance of The Trauma and Injury Severity Score (McFadden R2 = 0.56; AUC = 0.90). Conclusions: Commonly available clinical parameters could contribute to risk stratification, highlighting the prognostic importance of hemodynamic instability and metabolic response. This study was conducted on a small cohort as an exploratory analysis. Further research and validation based on multicentric cohorts are needed.