Maternal smoking during pregnancy increases the incidence and severity of respiratory infections in neonates. Surfactant proteins A and D (SP-A and SP-D, respectively) are components of pulmonary innate immunity and have an important role in defense against inhaled pathogens. The purpose of this study was to determine if nicotine exposure during the third trimester of pregnancy alters the expression of SP-A and SP-D of fetal lung epithelia. Pregnant ewes were assigned to four groups; a nicotine-exposed full-term and pre-term group, and control full-term and pre-term group. Lung tissue was collected for Western blot and IHC analysis of SP-A level, Western blot analysis of SP-D level and qPCR analysis of SP-A and SP-D mRNA expression. Exposure to nicotine significantly decreased SP-A gene expression (P = 0.01) and SP-A protein level in pre-term lambs. This finding suggests that maternal nicotine exposure during the last trimester of pregnancy alters a key component of lung innate immunity in offspring. Pediatr Pulmonol. 2010; 45:255–262.

This paper presents a simple model of MEMS thermopile based vacuum detector and experimental results obtained for sensors designed and fabricated at IHTM-IMTM. Sensors contain two thermopiles, each with 30 multilayer p⁺Si/Al thermocouples and p⁺Si or Al heater. Thermal isolating membrane has sandwich structure consisting of sputtered SiO₂ and residual n-Si layer. Dependence of output thermopile voltage on pressure was measured for sensors with different membrane thickness. Tests were performed in pressure range (10^-3-10⁵) Pa. Experimental results were compared with theoretical predictions.

Background: The aim of this study was to examine the effect of applying synchronized music and appropriate music selection on motivation for exercise and achieving better results in individuals of different fitness levels. Methods: The study included a total of 20 female participants, who for certain analyses were divided into two groups with slightly different levels of aerobic fitness: students from the Faculty of Sport and Physical Education (n = 10, age 23.0 ± 2.8), and middle-aged adult women exercising recreationally (n = 10, age 38.3 ± 11.6). Cardiopulmonary exercise testing (CPET) was conducted using a treadmill and gas analysis equipment, and motivational music qualities were assessed using the BMRI-2 questionnaire. The procedure included an initial maximal CPET test, echocardiography, and spirometric tests, followed by an interview to select preferred music tracks. A second CPET test was then performed with the chosen motivational music. The Borg Rating of Perceived Exertion (RPE) scale was used in both tests. Results: The internal consistency of the questionnaire was confirmed with a Cronbach’s Alpha of 0.982. The synchronized motivational music significantly improved cardiopulmonary parameters such as peak oxygen consumption (peak VO₂), oxygen consumption (VO₂) at the second ventilatory threshold (VT2), peak heart rate (peak HR), test duration, and reduced perceived exertion (RPE) at the beginning of the test and at the intensity level corresponding to the VT2. Negligible differences were noted between students and recreational athletes, so it can be assumed that music had an equal impact on these two groups of subjects. Conclusions: The study concluded that synchronous motivational music significantly enhances cardiopulmonary performance and reduces perceived fatigue during physical exertion by serving as a key motivational element and facilitating more economical movement.

Previous studies indicate that there is a large influence of the starting reaction time (RT) on sprint performance, but also that some recent changes in athletic rules may affect this correlation. This study aimed to examine the relationship between RT and results in: men’s (M60mH) and women’s (W60mH) disciplines 60 m over hurdles, 60 m hurdles in the heptathlon (H), 60 m hurdles in the pentathlon (P) at the recently held World Indoor Championship 2022 (WIC). The aim was also to determine whether there are differences in RT between M60mH and W60mH, M60mH and H, W60mH, and P, and between H and P. The study included 170 competitors who competed at the WIC. Pearson’s linear correlation coefficient (r) was used for correlation analysis, and the t-test for independent samples was used to examine differences between groups. A statistically significant correlation (r=0.23, N=72, p=0.05) was found between the results and RT in W60mH when observing the entire sample of participants (r2 = 5.29). Considering that in H (r=0.42, N=10, p=0.23, r2=0.18) and P (r=0.54, N=12, p=0.07, r2=0.29), a much higher correlation was obtained between results and RT than in competitors in the 60 m hurdles event, we believe that this is a consequence of different athletic rules that refer to a false start. There are no significant differences between RT for M60mH and W60mH, M60mH and H, W60mH, and P, and between H and P. Coaches should pay attention to developing all parts of the sprint race, including the reaction time.

The aim of the research is to analyze the trend in the number of participants in the Belgrade Marathon in the period 2007-2019: total, by gender and age categories, with a special reference to participants from Serbia. Using linear regressions, it was found that the total number of participants, both from Serbia and abroad, significantly increased; total number of male and female participants, both from Serbia and abroad, significantly increased ; the number of women is growing more than men every year, especially inthe sample of participants from Serbia; the number of participants by age categories of 5 years, for women and men from Serbia increased to the age group of 30-35 years, and then slowly decreased; the percentage of men and women in the 30-39 age category is increasing; the proportion of female seniors and female veterans is increasing. Statistically significant decreases: percentage of men in the 50-59 age category; percentage of male veterans. The percentage of male seniors didnot change. It can be concluded that the number of participants in the Belgrade Marathon, especially participants from Serbia, is increasing significantly, with a trend that exceeds many marathons in the world. The number of women is lower than in most marathons in the world, but the number of women from Serbia is increasing significantly compared to the number of men, which is in line with world trends. The number of male veterans is decreasing, which is different from most marathons in the world.

The Belgrade Marathon has been held since 1988 and has the longest tradition in the Western Balkans region. The trend in the number of participants in the Belgrade Marathon showed a significant increase in the 2007-2019 period. In addition to the global increase in the number of participants, a decreasing performance trends in marathon races has been noticed. The aim of this paper was to determine the trends in the performances of participants from Serbia in the Belgrade Marathon in the 2007-2019 period. The general cognitive assumption was that with an increase in the number of participants led to a decline in the average performance in the race. The results on the official website of the Belgrade Marathon were used as a source of data for this non-experimental study. All performances of the marathoners from Serbia (n = 3554) in the period 2007-2019 were analyzed. Linear regression analysis was used to assess the trend of the performances of all marathoners from Serbia, their distribution according to age groups by every 10 years, as well as the performances of the 10 first-ranked athletes in total and in each of the groups. The linear trend model on the sample of all marathoners from Serbia has shown that the performance became significantly worse over the years i.e., by 2:14 minutes per year. The trend of a significant decline in performance, ranging from 1:52 to 3:02 minutes per year, has been observed in all age groups of up to 50 years. The linear trend models obtained on the subsamples of the 10 first-ranked men in each of the analyzed age groups did not exceed the level of statistical significance, except in the group of males aged 50-60, where a significant performance trends improvement by 2:10 minutes a year was determined. The performances of competitors from Serbia at the Belgrade Marathon were declining in the examined period, along with a simultaneous increase in the number of participants in this event. It can be assumed that the average performance is declining due to an increasing number of recreational runners participating in the marathon, while the number of categorized runners is not increasing significantly, which in a way reflects conservatism and unchangeability within athletic long-distance races and marathon running events.