Dynamic networks are used in a variety of fields to represent the structure and evolution of the relationships between entities. We present a model which embeds longitudinal network data as trajectories in a latent Euclidean space. We propose Markov chain Monte Carlo (MCMC) algorithm to estimate the model parameters and latent positions of the actors in the network. The model yields meaningful visualization of dynamic networks, giving the researcher insight into the evolution and the structure, both local and global, of the network. The model handles directed or undirected edges, easily handles missing edges, and lends itself well to predicting future edges. Further, a novel approach is given to detect and visualize an attracting influence between actors using only the edge information. We use the case-control likelihood approximation to speed up the estimation algorithm, modifying it slightly to account for missing data. We apply the latent space model to data collected from a Dutch classroom, and a cosponsorship network collected on members of the U.S. House of Representatives, illustrating the usefulness of the model by making insights into the networks. Supplementary materials for this article are available online.
OBJECTIVE: To determine whether the seasonality of surgical site infections (SSIs) can be explained by changes in temperature.DESIGN: Retrospective cohort analysis.SETTING: The National Inpatient Sample database.PATIENTS: All hospital discharges with a primary diagnosis of SSI from 1998 to 2011 were considered cases. Discharges with a primary or secondary diagnoses of specific surgeries commonly associated with SSIs from the previous and current month served as our “at risk” cohort.METHODS: We modeled the national monthly count of SSI cases both nationally and stratified by region, sex, age, and type of institution. We used data from the National Climatic Data Center to estimate the monthly average temperatures for all hospital locations. We modeled the odds of having a primary diagnosis of SSI as a function of demographics, payer, location, patient severity, admission month, year, and the average temperature in the month of admission.RESULTS: SSI incidence is highly seasonal, with the highest SSI incidence in August and the lowest in January. During the study period, there were 26.5% more cases in August than in January (95% CI, 23.3–29.7). Controlling for demographic and hospital-level characteristics, the odds of a primary SSI admission increased by roughly 2.1% per 2.8°C (5°F) increase in the average monthly temperature. Specifically, the highest temperature group, >32.2°C (>90°F), was associated with an increase in the odds of an SSI admission of 28.9% (95% CI, 20.2–38.3) compared to temperatures <4.4°C (<40°F).CONCLUSIONS: At population level, SSI risk is highly seasonal and is associated with warmer weather.Infect Control Hosp Epidemiol2017;38:809–816
Embedding dyadic data into a latent space has long been a popular approach to modeling networks of all kinds. While clustering has been done using this approach for static networks, this paper gives two methods of community detection within dynamic network data, building upon the distance and projection models previously proposed in the literature. Our proposed approaches capture the time-varying aspect of the data, can model directed or undirected edges, inherently incorporate transitivity and account for each actor’s individual propensity to form edges. We provide Bayesian estimation algorithms, and apply these methods to a ranked dynamic friendship network and world export/import data.
Using the Nationwide Inpatient Sample and US weather data, we estimated the probability of community-acquired pneumonia (CAP) being diagnosed as Legionnaires’ disease (LD). LD risk increases when weather is warm and humid. With warm weather, we found a dose-response relationship between relative humidity and the odds for LD. When the mean temperature was 60°–80°F with high humidity (>80.0%), the odds for CAP being diagnosed with LD was 3.1 times higher than with lower levels of humidity (<50.0%). Thus, in some regions (e.g., the Southwest), LD is rarely the cause of hospitalizations. In other regions and seasons (e.g., the Mid-Atlantic in summer), LD is much more common. Thus, suspicion for LD should increase when weather is warm and humid. However, when weather is cold, dry, or extremely hot, empirically treating all CAP patients for LD might contribute to excessive antimicrobial drug use at a population level.
9 August 2017 in Journal of Interprofessional Care