Jingxin Zhao

Dr. Jingxin Zhao


Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 July 2019 in Annals of Biomedical Engineering
Verified
Journal Article
Closed access
JZJingxin Zhao
Jingxin Zhao
CLChangsheng Li
Changsheng Li
HRHongliang Ren
Hongliang Ren
MHMing Hao
Ming Hao
LZLicheng Zhang
Licheng Zhang
PTPeifu Tang
Peifu Tang

31 July 2023 in International Journal of Surgery
Verified
Journal Article
Open access
YWYilin Wang
Yilin Wang
YJYu Jiang
Yu Jiang
YLYan Luo
Yan Luo
XLXisheng Lin
Xisheng Lin
MSMi Song
Mi Song
LZLicheng Zhang
Licheng Zhang
Background: The prognostic nutritional index (PNI) has been proposed as a useful prognostic tool in multiple populations. However, its prognostic value has not been fully evaluated in the hip fracture population. We aimed to assess the relationship between PNI and postoperative complications as well as 2-year all-cause mortality in the hip fracture population. Materials and Methods: We included patients aged 45 or older who underwent surgery for hip fracture between 2000 and 2022. The baseline serum albumin and total lymphocyte count were used to calculate PNI with the following formula: 10×serum albumin level (g/dl)+0.005×total lymphocyte count (per mm3). Patients were classified into low, medium, and high categories based on tertiles of PNI (≤43.23, 43.23–47.35, and >47.35, respectively). Logistic regression and Cox proportional hazards models were used to calculate the odds ratio (OR) for postoperative compilations and the hazard ratio (HR) for mortality, adjusting for potential confounders. Results: Of 3351 hip patients, 236 (7.04%) developed postoperative complications, and 305 (9.10%) died during the 2-year follow-up. Compared to the low-category patients, the medium-category and high-category patients showed lower odds of postoperative complications (ORs 0.69, 95% CI 0.48–0.98; and 0.61, 95% CI 0.40–0.93, respectively), and lower hazards of 2-year mortality (HRs 0.66, 95% CI 0.49–0.88; and 0.61, 95% CI 0.42–0.88, respectively). These associations were robust across a series of analyses, including subgroup analyses and dose–response sensitivity analyses. Conclusion: PNI is an independent predictor of postoperative complications and 2-year all-cause mortality in hip fracture patients. PNI can be used to identify patients who may be at high risk of a poor prognosis.

27 May 2020 in Journal of Orthopaedic Surgery and Research
Verified
Journal Article
Open access
PDF file
RZRu-Yi Zhang
Ru-Yi Zhang
XSXiu yun Su
Xiu yun Su
JZJingxin Zhao
Jingxin Zhao
JLJiantao Li
Jiantao Li
LZLicheng Zhang
Licheng Zhang
PTPeifu Tang
Peifu Tang
Background: The femoral neck torsion angle (FNTA) is an important but often neglected parameter in assessments of the anatomical morphology of the femoral neck, which is often confused with the femoral neck anteversion angle (FNAA) in the current literature. Currently, the measurement methods reported in the literature all adopt the naked eye or two-dimensional (2D) visualization method, and the measurement parameters and details are not clearly defined. The objection of this research was to provide a reliable 3D method for determining the femoral neck axis, to improve the measurement method of the FNTA, and to analyze the anatomical and clinical significance of the results. Methods: Computed tomography (CT) data of 200 patients who received a lower extremity CT angiography examination were selected, and the bilateral femurs were reconstructed with three dimensional CT (3D CT). First, the 3D axis of the femoral neck was built. Second, the long axis of the cross section the femoral neck isthmus (FNI) and femoral neck basilar part (FNB) were confirmed by the “inertia axes” method, and the plane consisting of the long axis of the cross-section and the center of the femoral head was defined as the long axial plane. Third, the coronal plane of the proximal femur was determined through the long axis of the proximal femur and the femoral coronal. Finally, the FNTAs (the angles between the long axial planes and the coronal plane of the proximal femur) of FNI and FNB were measured. The size of FNTA was compared between the sexes and sides and different locations, the correlation between the parameters and age, height, and weight were evaluated. Results: The difference in FNTA was statistically significant between the isthmus and the basilar part (isthmus 30.58 ± 8.90° vs. basilar part 23.79 ± 3.98°; p < 0.01). Significant difference in the FNTA was observed between the sexes (males 31.99 ± 9.25° vs. females 27.49 ± 7.19°; p < 0.01). The increase in FNTA from the basilar part to the isthmus was 6.79 ± 8.06°, and the male (7.87 ± 8.57°) was greater than the female (4.44 ± 6.23°, p < 0.01). However, no significant difference in the values was observed between sides. Height exerted the greatest effect on the FNTA according to the correlation analysis (r = 0.255, p< 0.001). Conclusions: This study found a reliable 3D method for the determination of the femoral neck axis improved the measurement method of the FTNTA and made it more accurate and repeatable. The results provided a methodological basis and theoretical support for the research and development of internal fixation device for femoral neck fracture and the spatial configuration of implants in treatment. And the optimal opening point of the femoral medullary cavity was recommended to locate at the posterior position of the top of the femoral neck cross-section during hip replacement.

1 January 2015 in BioMed Research International
Verified
Journal Article
Open access
PDF file
XSXiu yun Su
Xiu yun Su
JZJingxin Zhao
Jingxin Zhao
ZZZhe Zhao
Zhe Zhao
LZLi-Cheng Zhang
Li-Cheng Zhang
CLChen Li
Chen Li
PTPeifu Tang
Peifu Tang
Purpose. To establish a new approach for measuring and locating the femoral intramedullary canal isthmus in 3-dimensional (3D) space.Methods. Based on the computed tomography data from 204 Chinese patients, 3D models of the whole femur and the corresponding femoral isthmus tube were reconstructed using Mimics software (Materialise, Haasrode, Belgium). The anatomical parameters of the femur and the isthmus, including the femur length and radius, and the isthmus diameter and height, were measured accordingly.Results. The mean ratio of the isthmus height versus the femoral height was 55 ± 4.8%. The mean diameter of the isthmus was 10.49 ± 1.52 mm. The femoral length, the isthmus diameter, and the isthmus tube length were significantly larger in the male group. Significant correlations were observed between the femoral length and the isthmus diameter (r=0.24,p<0.01) and between the femoral length and the isthmus height (r=0.6,p<0.01). Stepwise linear regression analyses demonstrated that the femoral length and radius were the most important factors influencing the location and dimension of the femoral canal isthmus.Conclusion. The current study developed a new approach for measuring the femoral canal and for optimization of customer-specific femoral implants.

28 October 2015 in BioMed Research International
Verified
Journal Article
Open access
PDF file
XSXiu yun Su
Xiu yun Su
ZZZhe Zhao
Zhe Zhao
JZJingxin Zhao
Jingxin Zhao
LZLi-Cheng Zhang
Li-Cheng Zhang
ALAn-Hua Long
An-Hua Long
PTPeifu Tang
Peifu Tang
Purpose. The human femur has long been considered to have an anatomical anterior curvature in the sagittal plane. We established a new method to evaluate the femoral curvature in three-dimensional (3D) space and reveal its influencing factors in Chinese population. Methods. 3D models of 426 femurs and the medullary canal were constructed using Mimics software. We standardized the positions of all femurs using 3ds Max software. After measuring the anatomical parameters, including the radius of femoral curvature (RFC) and banking angle, of the femurs using the established femur-specific coordinate system, we analyzed and determined the relationships between the anatomical parameters of the femur and the general characteristics of the population. Results. Pearsons correlation analyses showed that there were positive correlations between the RFC and height (, ) and the femoral length and RFC (, ) and a negative correlation between the femoral length and banking angle (, ). Stepwise linear regression analyses showed that the most relevant factors for the RFC and banking angle were the femoral length and gender, respectively. Conclusions. This study concluded that the banking angle of the femur was significantly larger in female than in male. Purpose. The human femur has long been considered to have an anatomical anterior curvature in the sagittal plane. We established a new method to evaluate the femoral curvature in three-dimensional (3D) space and reveal its influencing factors in Chinese population. Methods. 3D models of 426 femurs and the medullary canal were constructed using Mimics software. We standardized the positions of all femurs using 3ds Max software. After measuring the anatomical parameters, including the radius of femoral curvature (RFC) and banking angle, of the femurs using the established femur-specific coordinate system, we analyzed and determined the relationships between the anatomical parameters of the femur and the general characteristics of the population. Results. Pearsons correlation analyses showed that there were positive correlations between the RFC and height (, ) and the femoral length and RFC (, ) and a negative correlation between the femoral length and banking angle (, ). Stepwise linear regression analyses showed that the most relevant factors for the RFC and banking angle were the femoral length and gender, respectively. Conclusions. This study concluded that the banking angle of the femur was significantly larger in female than in male.

13 February 2018 in BioMed Research International
Verified
Journal Article
Open access
PDF file
JZJingxin Zhao
Jingxin Zhao
LZLicheng Zhang
Licheng Zhang
XSXiu yun Su
Xiu yun Su
ZZZhe Zhao
Zhe Zhao
YZYan-Peng Zhao
Yan-Peng Zhao
PTPeifu Tang
Peifu Tang
Purpose. The optimal closed reduction technique for unstable pelvic fractures remains controversial. The purpose of this study is to verify the effectiveness and report early experiences with the reduction of unstable pelvic fractures using a computer-aided pelvic reduction frame. Methods. From January 2015 to August 2016, a total of 10 patients with unilateral unstable pelvic fractures were included in this study. The surgical reduction procedure was based on the protocol of the computer-aided pelvic reduction frame that we proposed in a previous work. The quality of the reductions achieved using this system was evaluated with residual translational and rotational differences between the actual and virtual reduction positions of pelvis. The duration of the operation was recorded for quality control. Results. The mean times required to set up the frame, to complete the virtual surgery simulation, and to reduce the unstable pelvic fractures were 10.3, 20.9, and 7.5 min, respectively. The maximum residual translational and rotational displacements were less than 6.5 mm and 3.71 degrees, respectively. Conclusions. This computer-aided reduction frame can be a useful tool for the speedy and accurate reduction of unstable pelvic fractures. Further clinical studies should be conducted with larger patient samples to verify its safety and efficacy.