In this study, the biological activity of two-year-old Aronia melanocarpa (Michx.) Elliot plants in vitro micro propagated was evaluated. The phytochemical composition of ethanol extracts obtained from the leaves and fruits of the plant and their antibacterial activity against pathogenic bacteria were studied. In phytochemical screening experiments, secondary metabolites in the extracts were determined using qualitative tests: tannins, flavonoids, phenolic compounds, saponins and terpenoids. For antibacterial analysis, 30, 50, 70 and 90 % ethanol solutions of fruit and leaf extracts were prepared and according to the results obtained, 50 % ethanol extract was selected as the optimal concentration for antibacterial activity. Antibacterial activity was evaluated using the disc-well method and the pathogenic bacteria Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis were selected. The effect of the extracts on bacterial growth at different concentrations was determined by the diameter (mm) of the inhibition zones formed around the bacterial colonies. The experimental results showed that the antibacterial activity of leaf and fruit extracts increased in proportion to the increase in concentration. Especially at high concentrations (16–32 %), the fruit extract showed a significantly stronger antibacterial effect compared to the leaf extract. The results obtained substantiate the high prospects of leaf and fruit extracts of A. melanocarpa grown in vitro as natural antibacterial agents and the possibility of their application in the pharmaceutical and biotechnology fields.

The article presents information on the methods and results of studying the influence of extracts prepared from various organs of the caper plant (Capparis spinosa L.), which in the Samarkand region exhibits the absence of proliferative activity of monocyte macrophages and mouse RAW 264.7. There are many scientific and research works devoted to the study of the medicinal properties of Capparis spinose L. cappers growing in Uzbekistan, as well as many works dedicated to identifying the molecular mechanisms of the immunomodulatory properties of the plant, which have not yet been studied. In medicine, consuming ripe fruits of C. spinosa L. has long been known to treat various diseases' inflammatory processes, including stomach inflammation and intestinal bleeding processes of haemorrhoids. The experiments show that concentrations of plant extracts at a concentration of 25.5 ?l have a destructive effect on all samples. A concentration of 1 ?l reduces the proliferative activity of cells of all plant extracts, except for seed extract; as a result, when exposed to 1 ?l of seed extraction, the population level was the highest. In cells stimulated with LPS, the level of proliferation was high at a concentration of 0.5 ?l of extracts of flowers, fruits and roots. Cytotoxicity was observed in extratax leaves, which may explain the antibacterial activity.