Florin Mihaileanu

Dr. Florin Mihaileanu


Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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22 March 2024 in Diagnostics
Verified
Journal Article
Open access
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FMFlorin Mihaileanu
Florin Mihaileanu
PSPopa Stefan-Lucian
Popa Stefan-Lucian
Simona Mihaela GradSimona Mihaela Grad
Simona Mihaela Grad
DDDinu Iuliu Dumitrascu
Dinu Iuliu Dumitrascu
Abdulrahman IsmaielAbdulrahman Ismaiel
Abdulrahman Ismaiel
LDLiliana-Elisabeta David
Liliana-Elisabeta David
The initial clinical manifestation of acute mesenteric ischemia poses a diagnostic challenge, often leading to delays in identification and subsequent surgical intervention, contributing to adverse outcomes. Serum biomarkers, offering insights into the underlying pathophysiology, hold promise as prognostic indicators for acute mesenteric ischemia. This systematic review comprehensively explores the role of blood biomarkers in predicting clinical outcomes during follow-up for patients with mesenteric ischemia. A thorough literature search across the PubMed, Cochrane Library, and EMBASE databases yielded 33 relevant publications investigating the efficacy of serum biomarkers in predicting outcomes for mesenteric ischemia. Numerous studies underscore the utility of blood biomarkers in swiftly and accurately differentiating between causes of mesenteric ischemia, facilitating a prompt diagnosis. Elevated levels of specific biomarkers, particularly D-dimers, consistently correlate with heightened mortality risk and poorer clinical outcomes. While certain serum indicators exhibit substantial potential in associating with mesenteric ischemia, further research through rigorous human trials is imperative to enhance their consistent predictive ability during the follow-up period. This study underscores the diagnostic and prognostic significance of specific biomarkers for mesenteric ischemia, emphasizing the necessity for standardized procedures in future investigations.

30 January 2024 in Diagnostics
Verified
Journal Article
Open access
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BSBogdan Stancu
Bogdan Stancu
ACAlexandra Chira
Alexandra Chira
HCHorațiu F. Coman
Horațiu F. Coman
FMFlorin Mihaileanu
Florin Mihaileanu
RCRazvan Alexandru Ciocan
Razvan Alexandru Ciocan
OAOctavian Andercou
Octavian Andercou
It is quite common for portal vein thrombosis to occur in subjects who present predisposing conditions such as cirrhosis, hepatobiliary malignancies, infectious or inflammatory abdominal diseases, or hematologic disorders. The incidence of idiopathic portal vein thrombosis in non-cirrhotic patients remains low, and despite the intensive workup that is performed in these cases, in up to 25% of cases, there is no identifiable cause. If portal vein thrombosis is untreated, complications arise and include portal hypertension, cavernous transformation of the portal vein, gastroesophageal and even small intestinal varices, septic thrombosis, or intestinal ischemia. However, intestinal ischemia develops as a consequence of arterial thrombosis or embolism, and the thrombosis of the mesenteric vein accounts for about 10% of cases of intestinal ischemia. Although acute superior mesenteric vein thrombosis can cause acute intestinal ischemia, its chronic form is less likely to cause acute intestinal ischemia, considering the possibility of developing collateral drainage. Ileus due to mesenteric venous thrombosis is rare, and only a small number of cases have been reported to date. Most patients experience a distinct episode of acute abdominal pain due to ischemia, and in the second phase, they develop an obstruction/ileus. Acute superior mesenteric venous thrombosis is a rare condition that is still associated with a high mortality rate. The management of such cases of superior mesenteric venous thrombosis is clinically challenging due to their insidious onset and rapid development. A prompt and accurate diagnosis followed by a timely surgical treatment is important to save patient lives, improve the patient survival rate, and conserve as much of the patient’s bowel as possible, thus leading to fewer sequelae.

7 November 2023 in Biomedicines
Verified
Journal Article
Open access
PDF file
PSPopa Stefan-Lucian
Popa Stefan-Lucian
BSBogdan Stancu
Bogdan Stancu
Abdulrahman IsmaielAbdulrahman Ismaiel
Abdulrahman Ismaiel
DTDaria Claudia Turtoi
Daria Claudia Turtoi
VBVlad Dumitru Brata
Vlad Dumitru Brata
FMFlorin Mihaileanu
Florin Mihaileanu
Background: Small bowel disorders present a diagnostic challenge due to the limited accessibility of the small intestine. Accurate diagnosis is made with the aid of specific procedures, like capsule endoscopy or double-ballon enteroscopy, but they are not usually solicited and not widely accessible. This study aims to assess and compare the diagnostic effectiveness of enteroscopy and video capsule endoscopy (VCE) when combined with artificial intelligence (AI) algorithms for the automatic detection of small bowel diseases. Materials and methods: We performed an extensive literature search for relevant studies about AI applications capable of identifying small bowel disorders using enteroscopy and VCE, published between 2012 and 2023, employing PubMed, Cochrane Library, Google Scholar, Embase, Scopus, and ClinicalTrials.gov databases. Results: Our investigation discovered a total of 27 publications, out of which 21 studies assessed the application of VCE, while the remaining 6 articles analyzed the enteroscopy procedure. The included studies portrayed that both investigations, enhanced by AI, exhibited a high level of diagnostic accuracy. Enteroscopy demonstrated superior diagnostic capability, providing precise identification of small bowel pathologies with the added advantage of enabling immediate therapeutic intervention. The choice between these modalities should be guided by clinical context, patient preference, and resource availability. Studies with larger sample sizes and prospective designs are warranted to validate these results and optimize the integration of AI in small bowel diagnostics. Conclusions: The current analysis demonstrates that both enteroscopy and VCE with AI augmentation exhibit comparable diagnostic performance for the automatic detection of small bowel disorders.

16 January 2025 in Journal of Clinical Medicine
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Journal Article
Open access
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FMFlorin Mihaileanu
Florin Mihaileanu
MSMihaela Fadgyas Stanculete
Mihaela Fadgyas Stanculete
CGClaudia Diana Gherman
Claudia Diana Gherman
VBVlad Dumitru Brata
Vlad Dumitru Brata
APAlexandru-Marius Padureanu
Alexandru-Marius Padureanu
BSBogdan Stancu
Bogdan Stancu
Background: Obesity represents a global epidemic associated with significant health risks, including diabetes, cardiovascular disease, and certain cancers. Management strategies have evolved from focusing solely on weight reduction to emphasizing overall health improvements and mitigating associated risks. Methods: This narrative review analyzed the existing peer-reviewed literature across databases such as PubMed, Scopus, EMBASE, the Cochrane Library, and Google Scholar to examine the outcomes of bariatric surgery and its interplay with weight stigma. The review incorporated data from clinical studies, systematic reviews, and meta-analyses, focusing on bariatric surgery and its psychological impact, as well as approaches to mitigate stigma in bariatric care. Results: Bariatric surgery has emerged as the most effective intervention for sustained weight loss and the resolution of obesity-related comorbidities. However, individuals undergoing surgery frequently encounter weight stigma, both pre- and postoperatively, which manifests through discriminatory healthcare interactions, societal biases, and internalized self-criticism. These factors contribute to anxiety, depression, diminished healthcare engagement, and weight regain, ultimately affecting the long-term surgical outcomes. Conclusions: Addressing weight stigma in bariatric care is critical to optimizing outcomes. Interventions such as preoperative counseling, postoperative psychological support, and multidisciplinary care can mitigate the psychological and societal burdens of stigma. This review explores the intricate relationships between obesity, bariatric surgery outcomes, weight stigma, and the health-related quality of life (HRQOL).

28 January 2015 in Medicine and Pharmacy Reports
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Journal Article
Open access
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FMFlorin Mihaileanu
Florin Mihaileanu
SCStefan Chiorescu
Stefan Chiorescu
OGOvidiu Grad
Ovidiu Grad
VNVoicu Negrea
Voicu Negrea
HSHorațiu Silaghi
Horațiu Silaghi
AMAurel Mironiuc
Aurel Mironiuc
The surgical repair of inguinal hernia represents one of the most frequent procedures used in general surgery. The new surgical techniques are simpler, with a lower morbidity and recurrence of less than 2%. The laparoscopic totally extra-peritoneal (TEP) technique is contraindicated in complicated hernias (occlusion, incarceration) and in voluminous inguino-scrotal hernias.Purpose. the evaluation of the TEP technique, of the risk factors and of the postoperative results on the group of patients who have undergone surgery in the Surgical Clinic 2 Cluj Napoca.Material and method. The study is prospective, on a group of 40 patients operated with the TEP technique in the Surgical Clinic 2 during the period May 2013 – July 2014. The following have been assessed: the demographic data, the risk factors, the immediate complications, the recurrence of the hernias.Results. The average duration of hospitalization was 6.79 days. The intraoperative incidents were: 7 minimal peritoneal lesions with pneumoperitoneum and a hemorrhagic lesion of the epigastric vessels repaired endoscopically by the clipping of the lesion. There were 2 recurrences, 24 hours and 1 year after surgery, solved by the Lichtenstein technique. After 30 interventions, the average duration of the surgery was of 64 minutes, being longer in the case of bilateral hernias and being influenced by the team’s learning curve.Conclusions. The TEP technique is a safe option followed by a low rate of complications, a low recurrence rate and low intensity postoperative pain.

26 March 2026 in Medicina
Verified
Journal Article
Open access
PDF file
DDDinu Iuliu Dumitrascu
Dinu Iuliu Dumitrascu
PSPopa Stefan-Lucian
Popa Stefan-Lucian
Victor InczeVictor Incze
Victor Incze
DADarius-Stefan Amarie
Darius-Stefan Amarie
Leo GASPARILeo GASPARI
Leo GASPARI
IMIrina Magurean
Irina Magurean
Artificial intelligence (AI) is increasingly reshaping esthetic and reconstructive plastic surgery by improving measurement accuracy, treatment planning, and prediction of surgical outcomes. This article provides a scientific overview of current AI applications, including automated image analysis, machine-learning-based outcome forecasting, and generative models for preoperative simulation. AI-driven three-dimensional morphometrics allow precise, reproducible quantification of facial and body structures, supporting more objective assessments of symmetry, proportion, and contour. Predictive algorithms trained on large clinical datasets can estimate postoperative results and complication risks with higher consistency than traditional subjective evaluation. Intraoperative AI tools, such as real-time image guidance and robotic assistance, show potential to increase procedural precision and reduce variability. Despite these advances, important limitations persist. Algorithmic bias, restricted data diversity, opaque model architectures, and unresolved ethical concerns regarding data privacy and esthetic standardization challenge widespread clinical adoption. Overall, AI offers a powerful framework for enhancing precision and reproducibility in esthetic surgery, but its safe and responsible integration will require rigorous validation, transparent methodology, and continued human oversight.