The objective of this study was to examine the effect of a training program utilizing action perception technology (PAD) tools on improving the motor reaction times and neuromuscular capabilities of the upper and lower limbs compared to a traditional training program. Twenty-four female volleyball players competing in the Italian national championship were randomized into two groups of 12 athletes each: an experimental group (EG) and a control group (CG). A preliminary analysis confirmed the absence of significant differences in age and anthropometric characteristics between the groups. All the players underwent an initial battery of tests (pre-test), including Reaction Time simple Upper and Lower Limb (RTsUL and RTsLL) and Tapping Upper and Lower Limb (TUL and TLL). During a 6-week training program, the experimental group used exercises with a technological system of illuminated disks, while the control group followed the traditional training methods without advanced technology. At the end of the program, both groups were subjected to final tests (post-test). The main results show that after 6 weeks, both groups improved their performance compared to the initial tests. However, EG achieved significantly better results than CG in every test, with significant reductions in average times (ip%) of −14.9% in RTsUL (DX = −0.072 s, t = 23.2, p < 0.05, d = 6.7), −14.9% in RTsLL (DX = −0.091 s, t = 44.0, p < 0.05, d = 12.7), −10.6% in TUL (DX = −0.622 s, t = 42.0, p < 0.05, d = 12.1), and −10.7% in TLL (DX = −0.983 s, t = 43.1, p < 0.05, d = 12.4). The use of light-based perception–action technology devices in volleyball training has shown potential for significantly improving movement speed and reaction time. However, further research is needed to determine whether these improvements actually translate into enhanced overall performance in competitive contexts compared to the traditional training methods.

Objectives: This study aimed to evaluate the effectiveness of a structured multisport play-based program on the development of motor coordination in Italian children aged 6 to 10 years, using the Körperkoordinationstest für Kinder (KTK). Methods: An observational cross-sectional design was applied, involving 320 children (mean age 8.1 ± 1.4 years; 52% male) from the Puglia region in southern Italy. Participants were divided into a Multisport Group (MG; n = 162), engaged in multisport activities, and a Curricular Group (CG; n = 158), involved in standard physical education programs. Anthropometric measurements (weight, height, and BMI) and motor coordination outcomes (Motor Quotient, MQ) were assessed using the KTK. Statistical analyses included ANOVA, Pearson’s correlations, and logistic regression models. Results: The results showed that the MG achieved significantly higher MQ scores (108.3 ± 12.5) compared to the CG (101.2 ± 13.4; p < 0.001). Moreover, higher BMI values were significantly associated with an increased risk of lower MQ scores (OR = 2.35; 95% CI: 1.45–3.81; p < 0.001), indicating that children with elevated BMI had more than twice the likelihood of showing impaired motor coordination. Strong positive correlations were found between all KTK subtests and the total MQ score. Conclusions: Participation in structured multisport programs appears to enhance motor coordination in children and may represent a valuable educational and preventive strategy within primary school physical education and public health interventions.

Balance is a key determinant of movement quality and injury prevention in dance, yet targeted dynamic-balance training is rarely embedded in adolescent curricula. This controlled experimental study evaluated a 10-week proprioceptive add-on protocol integrated into Latin American dance practice on neuromotor performance in adolescent female dancers. One hundred twenty-four participants were allocated to an experimental group (EG; n = 62) or a control group (CG; n = 62). Outcomes were the Y Balance Test (YBT; composite and inter-limb asymmetry), Pediatric Reach Test (PRT; anterior and lateral), Single-Leg Landing Stability Test (SLLST; time to stabilization), and countermovement jump (CMJ; bilateral and single-leg). The EG completed 25–30 min of progressive balance work twice weekly before class, while the CG continued standard technical training with matched volume. Compared with the CG, the EG showed clear pre–post improvements in YBT (bilateral composite increased; asymmetry decreased), PRT (anterior and lateral increased), CMJ (bilateral and right single-leg increased), and SLLST (time to stabilization decreased), with significant group × time interactions across domains. Specifically, improvements were significant for Y Balance Test composite scores (p < 0.001), Pediatric Reach Test (p ≤ 0.01), countermovement jump (p < 0.05), and time to stabilization (p ≤ 0.01), confirming robust within- and between-group effects. These findings indicate specific neuromotor adaptations attributable to the integrated protocol. Beyond performance enhancement, the proprioceptive program may contribute to injury prevention, better postural efficiency, and safer execution of complex dance movements in adolescent dancers.

Background: Reaction time and coordination are key performance components in team sports such as handball, particularly during the developmental years. Integrating visual and cognitive stimuli through smart technologies has been shown to facilitate motor skill development in young athletes. Methods: This study evaluated the effects of a BlazePod-based training protocol on reaction time, visuomotor coordination, movement quickness, and change-of-direction performance in junior male handball players aged 12–14 years. Thirty-two athletes (mean age = 13.37 ± 0.29 years) were randomly assigned to an experimental group (n = 16), in which the traditional neuromotor/coordination block of regular practice was replaced with BlazePod-based drills three times per week for eight weeks, or to a control group (n = 16), which trained the same capacities with traditional handball-specific exercises without technology. Training frequency (3 sessions/week), session duration (90 min), and the workload of the 30 min neuromotor block were matched between groups. Motor performance was assessed using four tests: Focus Reactions, Fast Feet, Clap Challenge, and the Agility T-Test. Paired- and independent-samples t-tests were applied to compare pre- and post-intervention scores. Results: The experimental group showed significant within-group improvements in Focus Reactions (p = 0.002) and AgilTT_ShuffleLeft (p = 0.014), whereas the control group showed no improvements and a small but significant worsening in Focus Reactions. Between-group comparisons at post-test revealed significant differences in favor of the experimental group for Fast Feet (p = 0.036), Clap Challenge (p = 0.008), AgilTT_Overall (p < 0.001), and AgilTT_SprintBack (p = 0.003). Conclusions: The integration of BlazePod technology into handball training produced measurable improvements in reaction speed and lateral agility among junior players. These findings suggest that technology-assisted neuromotor training represents a viable training modality that can replace a traditional neuromotor block within youth handball practice while maintaining overall training dose.

Major disease complications for patients with essential thrombocythemia (ET) include thrombosis and fibrotic or leukemic transformation. Calreticulin (CALR) mutation type 1 frequencies in ET are estimated between 7% and 11% and ET patients carrying CALR type 1 mutation are associated with lower risk of thrombosis but higher risk of myelofibrosis transformation compared to ET patients with JAK2 mutation. Leukemic transformation rates at 20 years are estimated at less than 5% for ET and risk factors for leukemic transformation are advanced age, thrombosis history, leukocytosis, and anemia. Amongst the subtypes of blast phase myeloproliferative neoplasms, acute promyelocytic leukemia is extremely rare. Herein, we present a case of a promyelocytic blast crisis of post-ET myelofibrosis with associated life-threatening splanchnic vein thrombosis. This case suggests that inflammation plays a key role in thrombotic events and fibrotic/leukemic transformation in ET patients, regardless the molecular landscape.

Background: Kitesurfing is a wind-propelled water sport performed in highly variable environmental conditions. Scientific evidence describing internal load under standardized ecological sea constraints remains limited. Aim: This study aimed to characterize cardiovascular and perceptual responses during a standardized kitesurfing session and to examine associations among heart rate-based internal load indices, session rating of perceived exertion, and global navigation satellite system-derived external output variables. Methods: A total of 112 male recreational kitesurfers (32.1 ± 6.8 years) completed a 40–50 min standardized session under monitored wind conditions (17–22 knots) along a predefined approximately 800 m course. Heart rate was continuously recorded, and session rating of perceived exertion (Borg Category-Ratio 10 scale) was collected 30 ± 5 min post-session. Training impulse, mean percentage of maximal heart rate, and session rating of perceived exertion load were calculated. Pearson correlation analyses with bootstrapping (1000 resamples) and five percent trimming were performed, with statistical significance set at 0.05. Results: Sessions were performed at 78.4 ± 9.1 percent of maximal heart rate. Training impulse and mean percentage of maximal heart rate were strongly associated (correlation coefficient = 0.90, probability value < 0.001), reflecting the shared heart rate-based structure of these metrics. Training impulse showed a moderate association with session rating of perceived exertion load (correlation coefficient = 0.46, probability value < 0.001). No significant associations were observed between internal load indices and global navigation satellite system-derived mean speed (correlation coefficient = −0.14, probability value = 0.149) or distance (correlation coefficient = 0.06, probability value = 0.555). Sensitivity analyses confirmed the stability of the observed associations. Conclusions: Under standardized ecological sea conditions, kitesurfing sessions were characterized by sustained high submaximal cardiovascular intensity. Heart rate-based and perceptual measures showed consistent associations within this protocol, whereas global navigation satellite system-derived external outputs were not significantly related to internal load indices. Within the limits of this cross-sectional ecological design, the combined use of one heart rate-based indicator and session rating of perceived exertion offers a coherent and practically interpretable description of session internal load in open-water kitesurfing.