Domenico Alesi

Dr. Domenico Alesi

orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 April 2020 in Knee Surgery, Sports Traumatology, Arthroscopy
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Journal Article
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DADomenico Alesi
Domenico Alesi
GMGiulio Maria Marcheggiani Muccioli
Giulio Maria Marcheggiani Muccioli
TSTommaso Roberti di Sarsina
Tommaso Roberti di Sarsina
MBMarco Bontempi
Marco Bontempi
NPNicola Pizza
Nicola Pizza
LBLaura Bragonzoni
Laura Bragonzoni

1 July 2019 in Spine
Verified
Journal Article
Closed access
PBPasquale De Bonis
Pasquale De Bonis
CICorrado Iaccarino
Corrado Iaccarino
AMAntonio Musio
Antonio Musio
AMAntonio Martucci
Antonio Martucci
FIFederico De Iure
Federico De Iure
GLGiorgio Lofrese
Giorgio Lofrese
Study Design.: Retrospective multicenter study. Objective.: Analysis of impact of conservative and surgical treatments on functional outcome of geriatric odontoid fractures. Summary of Background Data.: Treatment of odontoid fractures in aged population is still debatable. Methods.: One hundred fourty-seven consecutive odontoid fractures in elderly patients were classified according to Anderson-D’Alonzo and Roy-Camille classifications. Philadelphia type collar was always positioned and kept as a treatment whenever acceptable. Halo-vest, anterior screw fixation, C1–C2 posterior arthrodesis, and occipito-cervical fixation were the other treatments adopted. Conservative or surgical treatment strategy was more significantly influenced by antero-posterior displacement (< or >5 mm) and by surgeon decision. On admission ASA, modified Rankin scale (mRS-pre) and Charlson Comorbidity Index (CCI) were assessed. Modified Rankin scale (mRS-post), Neck Disability Index (NDI), and Smiley Webster Pain Scale (SWPS) were administered 12 to 15 months after treatment to estimate functional outcome in terms of general disability, neck-related disability, and ability to return to work/former activity. Risk of treatment crossover was calculated considering factors affecting outcome. Fracture healing process in terms of fusion-stability, no fusion-stability, no fusion-no stability was evaluated at 12 months through a cervical computed tomography (CT) scan. Dynamic cervical spine x-rays were obtained whether necessary. No fusion-stability was considered an adequate treatment goal in our geriatric population. Chi square/Fisher exact test and logistic regression were performed for statistical anal. Results.: Overall 67 patients were treated conservatively whereas 80 underwent surgery. Collar was adopted in 45 patients, while anterior odontoid fixation and C1–C2 posterior arthrodesis were preferred for 30 patients each. 79.8% of patients showed good outcomes according to NDI. No significant differences were observed between patients of 65 to 79 years and more than or equal to 80 years (P = 0.81). CCI greatly correlated with mRS-post, with higher indexes in 68.8% of cases characterized by good outcomes (P = 0.05). mRS-pre correlated with NDI (P < 0.000001) and mRS-post (P = 0.04). CCI, mRS-pre, and surgery were associated with worse NDI, while both C1–C2 posterior arthrodesis and occipito-cervical stabilization were associated with worse mRS-post, respectively in 40% and 30% of cases. Younger patients had a higher risk of treatment crossover. Conclusion.: mRS-pre and CCI provided two independent predictive values respectively for functional outcome and post-treatment disability. Compared with conservative immobilizations, surgery revealed no advantages in the elderly in terms of functional outcome. Level of Evidence: 3

6 April 2021 in International Orthopaedics
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Journal Article
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SZStefano Zaffagnini
Stefano Zaffagnini
SPStefano Di Paolo
Stefano Di Paolo
AMAmit Meena
Amit Meena
DADomenico Alesi
Domenico Alesi
RZRaffaele Zinno
Raffaele Zinno
LBLaura Bragonzoni
Laura Bragonzoni

12 June 2021 in Knee Surgery, Sports Traumatology, Arthroscopy
Verified
Journal Article
Closed access
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TSTommaso Roberti di Sarsina
Tommaso Roberti di Sarsina
DADomenico Alesi
Domenico Alesi
SPStefano Di Paolo
Stefano Di Paolo
RZRaffaele Zinno
Raffaele Zinno
NPNicola Pizza
Nicola Pizza
LBLaura Bragonzoni
Laura Bragonzoni

2 January 2021 in Knee Surgery, Sports Traumatology, Arthroscopy
Verified
Journal Article
Open access
PDF file
NPNicola Pizza
Nicola Pizza
SPStefano Di Paolo
Stefano Di Paolo
RZRaffaele Zinno
Raffaele Zinno
GMGiulio Maria Marcheggiani Muccioli
Giulio Maria Marcheggiani Muccioli
PAPiero Agostinone
Piero Agostinone
LBLaura Bragonzoni
Laura Bragonzoni
Purpose: To investigate if postoperative clinical outcomes correlate with specific kinematic patterns after total knee arthroplasty (TKA) surgery. The hypothesis was that the group of patients with higher clinical outcomes would have shown postoperative medial pivot kinematics, while the group of patients with lower clinical outcomes would have not.Methods: 52 patients undergoing TKA surgery were prospectively evaluated at least a year of follow‐up (13.5 ± 6.8 months) through clinical and functional Knee Society Score (KSS), and kinematically through dynamic radiostereometric analysis (RSA) during a sit‐to‐stand motor task. Patients received posterior‐stabilized TKA design. Based on the result of the KSS, patients were divided into two groups: “KSS > 70 group”, patients with a good‐to‐excellent score (93.1 ± 6.8 points, n = 44); “KSS < 70 group”, patients with a fair‐to‐poor score (53.3 ± 18.3 points, n = 8). The anteroposterior (AP) low point (lowest femorotibial contact points) translation of medial and lateral femoral compartments was compared through Student’s t test (p < 0.05).Results: Low point AP translation of the medial compartment was significantly lower (p < 0.05) than the lateral one in both the KSS > 70 (6.1 mm ± 4.4 mm vs 10.7 mm ± 4.6 mm) and the KSS < 70 groups (2.7 mm ± 3.5 mm vs 11.0 mm ± 5.6 mm). Furthermore, the AP translation of the lateral femoral compartment was not significantly different (p > 0.05) between the two groups, while the AP translation of the medial femoral compartment was significantly higher for the KSS > 70 group (p = 0.0442).Conclusion: In the group of patients with a postoperative KSS < 70, the medial compartment translation was almost one‐fourth of the lateral one. Surgeons should be aware that an over‐constrained kinematic of the medial compartment might lead to lower clinical outcomes.Level of evidence: II.

27 October 2018 in Knee Surgery, Sports Traumatology, Arthroscopy
Verified
Journal Article
Closed access
PDF file
LBLaura Bragonzoni
Laura Bragonzoni
GMGiulio Maria Marcheggiani Muccioli
Giulio Maria Marcheggiani Muccioli
MBMarco Bontempi
Marco Bontempi
TSTommaso Roberti di Sarsina
Tommaso Roberti di Sarsina
UCUmberto Cardinale
Umberto Cardinale
SZStefano Zaffagnini
Stefano Zaffagnini