SUMMARY: Nanohybrid resin composites present conventional particles to be mixed with nanomeric fillers and, therefore, it is unknown whether they may perform similarly to nanofilled or microhybrid resins. The current study investigated the properties of nanohybrid resins (TPH³, Grandio, Premise, Concept Advanced) in comparison with a nanofilled (Supreme XT) and a microhybrid (Z250) composite. The inorganic fillers were characterized by SEM/EDS analysis. Diametral tensile strength (DTS), surface roughness before and after toothbrush abrasion, Knoop Hardness (KHN), water sorption and solubility were evaluated. The data were separately analyzed by ANOVA and the Student-Newman-Keuls' tests (p<0.05). The results of all analyses were material-dependent. Noticeable differences in filler size and shape were detected among the materials. Supreme XT generally showed higher DTS and KHN compared to all the nanohybrids and also showed lower surface roughness before and after toothbrush abrasion compared to most of the materials tested. Similar results were generally detected for the nanohybrids compared with the microhybrid material. In conclusion, the nanohybrid resins generally presented inferior properties compared with the nanofilled composite and either similar or slightly better properties compared to the microhybrid material. Under clinical conditions, nanohybrid resins may not perform similarly to nanofilled materials.

The number of carbon atoms and/or ester/polyether groups in spacer chains may influence the interaction of functional monomers with calcium and dentin. The present study assessed the chemical interaction and bond strength of 5 standard-synthesized phosphoric-acid ester functional monomers with different spacer chain characteristics, by atomic absorption spectroscopy (AAS), ATR-FTIR, thin-film x-ray diffraction (TF-XRD), scanning electron microscopy (SEM), and microtensile bond strength (μTBS). The tested functional monomers were 2-MEP (two-carbon spacer chain), 10-MDP (10-carbon), 12-MDDP (12-carbon), MTEP (more hydrophilic polyether spacer chain), and CAP-P (intermediate hydrophilicity ester spacer). The intensity of monomer-calcium salt formation measured by AAS differed in the order of 12-MDDP=10-MDP>CAP-P>MTEP>2-MEP. FTIR and SEM analyses of monomer-treated dentin surfaces showed resistance to rinsing for all monomer-dentin bonds, except with 2-MEP. TF-XRD confirmed the weaker interaction of 2-MEP. Highest µTBS was observed for 12-MDDP and 10-MDP. A shorter spacer chain (2-MEP) of phosphate functional monomers induced formation of unstable monomer-calcium salts, and lower chemical interaction and dentin bond strength. The presence of ester or ether groups within longer spacer carbon chains (CAP-P and MTEP) may affect the hydrophilicity, μTBS, and also the formation of monomer-calcium salts.