The global shortage of clean water is a major problem, even in water-rich regions. To solve this problem, low-cost and energy-efficient water treatment methods are needed. Membrane separation technology (MST), as a separation method with low energy consumption, low cost, and good separation effect, has been widely used to deal with seawater desalination, resource recovery, industrial wastewater treatment, and other fields. With the continuous progress of scientific and technological innovation and the increasing demand for use, NF/RO membranes based on the TFC structure are constantly being upgraded. This paper presents the recent research progress of NF and RO membranes based on TFC structures and their applications in different fields, especially the formation mechanism and regulation of selective layer structures and the modification methods of selective layers. Our summary provides fundamental insights into the understanding of NF and RO membrane processes and hopefully triggers further thinking on the development of membrane filtration process optimization.

Optimizing the structure of the polyamide (PA) layer to improve the separation performance of PA thin-film composite (TFC) membranes has always been a hot topic in the field of membrane preparation. As novel crystalline materials with high porosity, multi-functional groups, and good compatibility with membrane substrate, metal–organic frameworks (MOFs) have been introduced in the past decade for the modification of the PA structure in order to break through the separation trade-off between permeability and selectivity. This review begins by summarizing the recent progress in the control of MOF-based thin-film nanocomposite (TFN) membrane structures. The review also covers different strategies used for preparing TFN membranes. Additionally, it discusses the mechanisms behind how these strategies regulate the structure and properties of PA. Finally, the design of a competent MOF material that is suitable to reach the requirements for the fabrication of TFN membranes is also discussed. The aim of this paper is to provide key insights into the precise control of TFN-PA structures based on MOFs.