This study examines the impact of a dual cure activator (DCA) when applied in combination with self-adhesive resin cements on the zirconia. Sixty zirconia were prepared in compliance with the manufacturer’s directions. The specimens were randomly assigned to each group under the dark condition, following DCA and self-adhesive resin cements [RelyX universal resin cement (RXS); Maxcem elite chroma (MAC); Panavia SA cement multi (PSM)]; group 1, RXS; group 2, MAC; group 3, PSM; group 4, DCA + RXS; group 5, DCA + MAC; and group 6, DCA + PSM. The resin composite was fixed to the zirconia, surface-treated, and maintained in a dark container for 30 min. The specimens were kept in an incubator at a temperature of 37 degrees Celsius for 24 h. The universal testing device was employed to compute the shear bond strength (SBS). A stereomicroscope was used to analyze the fractured types. The data were analyzed employing the one-way ANOVA and Tukey’s test. Group 2 had the lowest SBS (4.93 ± 0.53 MPa). Group 1 (11.17 ± 0.86 MPa) and group 3 (11.48 ± 1.17 MPa) were not significantly different in SBS. Group 6 (15.61 ± 0.68 MPa) had the highest SBS but was not significantly different from group 4 (15.45 ± 1.20 MPa). The findings show that treating the zirconia surface with DCA before using the self-curing mode of self-adhesive resin cements is the best way to improve the bond between the zirconia and resin cement.