Erythema multiforme is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus, medications, autoimmune diseases, and malignancies, but the most common cause is infection by herpes simplex virus. The most characteristic feature is the presence of “target lesions.” There are no specific diagnostic tests for EM, and the diagnosis is based on clinical signs and symptoms and biopsy if required. We report a case of recurrent herpes‐associated erythema multiforme managed with prophylactic acyclovir for 6 months: a 17‐year‐old boy had recurrent cutaneous lesions as well as lesions in the oral cavity and lips. Positive serology for herpes simplex virus and histopathological examination confirmed the diagnosis.

Introduction: Psoriasis is a chronic inflammatory skin disease that typically affects the extremities, trunk, scalp, and nails. Psoriatic cheilitis as an exclusive presentation is very rare and to our knowledge, only 6 cases have been reported to date. The absence of cutaneous lesions causes diagnostic difficulties that can result in misdiagnosis and inadequate treatment. Observation: We reported the case of a 21-year-old woman with a seven years history of scaly plaques of the vermillion of the lips as the only disease manifestation. Her cheilitis was associated with significant psychiatric morbidity. Oral biopsy showed a psoriasiform pattern. Local applications of betamethasone was proposed. Discussion: Although lip psoriasis is extremely rare, it can be the sole presentation of psoriasis even in the absence of accompanying skin lesions, other oral manifestations or a family history of psoriasis. Conclusion: Lip psoriasis should be considered in the differential diagnosis of chronic or recurrent treatment-resistant labial lesions.

Background: Candida albicans is a common fungal pathogen responsible for oral infections, especially in immunocompromised individuals. Essential oils, derived from plants such as cinnamon and cloves, have been reported to have antifungal properties. This study aimed to compare the antifungal activity of cinnamon and cloves essential oils against oral C. albicans while determining the minimum fungicidal concentration for each extract. Materials and Methods: In this comparative in vitro study, four different volumes (0.25 μL, 0.5 μL, 1 μL, and 2 μL) of cinnamon and cloves essential oils were tested for their antifungal activity against C. albicans isolated from 2 strains of oral samples. Their minimum inhibitory concentration (MIC) was determined using a reproducible microdilution method allowing precise measurement of the essential oil’s antifungal activity and determining the lowest concentration that can inhibit fungal growth. Results: Both cinnamon and cloves essential oils exhibited significant antifungal activity against oral C. albicans starting at a dose of 0.25 μL for cinnamon and 1 μL for cloves. The MIC values for cinnamon essential oil were lower than those for cloves essential oil, with 0.2 μL compared to 1 μL, respectively. Conclusion: Cinnamon and cloves essential oils demonstrated potent antifungal activity against oral C. albicans in vitro, with cinnamon essential oil showing superior efficacy. These findings suggest the potential of these essential oils as alternative therapeutic agents for the management of oral candidiasis. Further research is warranted to explore their clinical application in immunocompromised patients.

Methimazole is a widely used antithyroid medication with a well-documented risk of hematological adverse effects, particularly agranulocytosis. While syste

The tongue, as a multifunctional organ, exhibits a variety of physiological characteristics and pathological alterations. Identifying and understanding these variations is crucial for ensuring an accurate diagnosis and appropriate management. This article explores the main common physiological variations, such as geographic tongue, fissured tongue, etc., as well as pathological conditions, including elementary lesions such as vesicles, bullae, erosions, ulcers, plaques, along with surface changes (atrophy), color changes (coatings, pigmentation), or even shape alterations (infiltrations). It discusses current diagnostic tools and therapeutic approaches while emphasizing the importance of regular monitoring to prevent complications and maintain optimal oral health.

Long-term data evaluating both patient satisfaction and oral health-related quality of life (OHRQoL) in anterior maxillary implant rehabilitation are still limited, making this investigation highly relevant. This study aimed to evaluate patient satisfaction and OHRQoL 5 years after anterior maxillary implant placement. It specifically assessed long-term satisfaction with implant-supported restorations in the aesthetic zone, the impact on OHRQoL, and key clinical and prosthetic factors influencing perceived treatment success. A prospective study was conducted at the University Hospital of Farhat Hached, Sousse, Tunisia, from March to June 2024. Eligible patients who underwent anterior maxillary implant placement between 2018 and 2019 were included. Patients with fixed implant-supported restorations and good systemic health were eligible, while those with parafunctional habits or incomplete follow-up data were excluded. Satisfaction was assessed using a Visual Analog Scale (VAS), and OHRQoL was measured using the Oral Health Impact Profile (OHIP)-14 and Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) questionnaires. A total of 50 patients participated. The sample size was determined based on an expected satisfaction rate of 80%, with a 95% confidence interval and a 10% margin of error, resulting in a required minimum of 47 participants. Data analysis was performed using SPSS version 20. Descriptive statistics summarized demographics, satisfaction scores, and OHRQoL outcomes. Inferential analyses included paired t-tests and Wilcoxon signed-rank tests to compare baseline and 5-year follow-up data. Spearman's correlation was used to examine relationships between implant-related factors and satisfaction or OHRQoL scores, while multivariate regression identified predictors of long-term satisfaction. A p-value of < 0.05 was considered statistically significant. Fifty patients (mean age: 36.5 ± 5.3 years) participated, with a 98.04% implant survival rate. At 5 years, 86.2% reported high satisfaction, with a mean VAS score of 92.8%. Phonetic outcomes received a 100% satisfaction rate, while chewing comfort and stability were also highly rated (94.0 and 93.7%, respectively). Esthetic satisfaction was reported by 85.0% of patients, and 67.5% had no difficulty maintaining hygiene. The OHIP-14 median score of 9.0 indicated minimal OHRQoL impairment. PIDAQ results showed that while most patients were satisfied with esthetics, some experienced psychosocial impacts. Five years after anterior maxillary implant placement, patients reported high satisfaction, especially regarding phonetics, chewing comfort, and esthetics. The minimal OHRQoL impact and low PIDAQ scores highlight the positive psychosocial effects of implant restorations. These results suggest that long-term evaluation of functional and psychological outcomes should be integrated into clinical decision-making and future prospective studies.