Erythema multiforme is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus, medications, autoimmune diseases, and malignancies, but the most common cause is infection by herpes simplex virus. The most characteristic feature is the presence of “target lesions.” There are no specific diagnostic tests for EM, and the diagnosis is based on clinical signs and symptoms and biopsy if required. We report a case of recurrent herpes‐associated erythema multiforme managed with prophylactic acyclovir for 6 months: a 17‐year‐old boy had recurrent cutaneous lesions as well as lesions in the oral cavity and lips. Positive serology for herpes simplex virus and histopathological examination confirmed the diagnosis.

Dentigerous cysts are the most common type of developmental odontogenic cysts. Multiple devices has been described for decompression. The current case report describes the use of a custom-made decompression appliance, designed through a digital workflow, in managing dentigerous cysts. A 7-year-old male patient with no prior medical history was referred to our oral surgery department due to swelling on the left side of the lower jaw. Upon intraoral examination and cone-beam computed tomography (CBCT), a provisional diagnosis of an inflammatory dentigerous cyst related to the impacted premolar was made. A digital decompression appliance was planned using EXOCAD (Exocad Gmbh, Darmstadt, Germany), and produced using a stereolithography (SLA) 3D printer. The appliance were delivered on the day of the cystostomy after extraction of the deciduous molar (tooth 85). In this report, the advancements in digital design technologies were explored enabling the creation of customized cyst decompression devices. Various stages of the design process were discussed, including 3D modeling, material selection, and the integration of digital workflows in the fabrication process. Additionally, the benefits of using such devices were addressed, including improved patient outcomes, enhanced precision in treatment, and the reduction of surgical complications.

Systemic scleroderma, a multifaceted autoimmune disease, often presents with significant orofacial manifestations that pose substantial challenges in clinical management. This chapter provides a comprehensive review of the various orofacial complications associated with systemic scleroderma, including microstomia, xerostomia, periodontal disease, and temporomandibular joint disorders. The pathophysiological mechanisms underlying these manifestations are explored, highlighting the importance of early recognition and intervention. Additionally, this chapter discusses current therapeutic approaches, emphasizing the need for a multidisciplinary strategy that encompasses physical therapy, surgical options and prosthetic rehabilitation. This review aims to enhance understanding among healthcare professionals and improve patient outcomes through a more informed and integrated approach to care.

Inflammatory Fibrous Hyperplasia (IFH) is a benign lesion induced by chronic denture trauma that reduces vestibular depth and complicates prosthetic rehabilitation. This case report describes the comprehensive management of a 64-year-old edentulous man presenting with severe ridge resorption and...