As the population ages, promoting healthy aging through targeted interventions becomes increasingly crucial. Growing evidence suggests that dietary interventions can significantly impact this process by modulating fundamental molecular pathways. This review focuses on the potential of targeted dietary strategies in promoting healthy aging and the mechanisms by which specific nutrients and dietary patterns influence key pathways involved in cellular repair, inflammation, and metabolic regulation. Caloric restriction, intermittent fasting, the Mediterranean diet, as well as the ketogenic diet showed promising effects on promoting healthy aging, possibly by modulating mTORC1 AMPK, an insulin signaling pathway. By understanding the intricate interplay between diet and molecular pathways, we can develop personalized dietary strategies that not only prevent age-related diseases, but also promote overall health and well-being throughout the aging process.
Background: Social prescribing initiatives are tailored coaching programs created to assist participants in improving their personal circumstances and might constitute a creative way to enhance public and preventive health as we work toward providing universal financially sustainable healthcare. Methods: We conducted a scoping review with the aim of summarizing the main global trends on social prescribing and to identify the existing resources and potential targets of social prescribing in Romania. Results: One of the main concerns that arose from this review is the lack of defined pathways to access social programs and the lack of link workers, recognized as a valuable form of support in directing people toward the most appropriate intervention, necessary to increase long-term sustainability. We also acknowledge the importance of primary care in social prescribing, especially in prevention. The level of awareness and the capacity of primary care providers to identify the need for social prescription to increase the awareness of resources and encourage teamwork should be increased. Conclusions: By focusing on these areas, we can enhance the health and well-being of the population and fully realize the benefits of social prescribing in Romania. Further research and collaboration on social prescribing are crucial for optimizing its impact in Romania.
Background/Objectives: Romania faces a shortage of family physicians, particularly in rural areas. Undergraduate Family Medicine rotations may influence students’ perceptions before residency selection, but the contribution of rural versus urban training settings remains insufficiently documented. This study examined differences between post-rotation perceptions and students’ recalled pre-rotation perceptions, and explored whether these differences varied according to placement setting. Methods: This single-centre study used a single-administration retrospective pretest–posttest observational design. After completing the mandatory one-month Family Medicine rotation, 141 sixth-year medical students completed a questionnaire containing recalled pre-rotation and post-rotation ratings on 12 five-point Likert items. Paired comparisons used Wilcoxon signed-rank tests; multiple-testing corrections were applied within the defined item families. A baseline-adjusted model with robust standard errors examined rural placement. Results: The composite score increased from 3.62 ± 0.84 to 4.10 ± 0.74 (mean change 0.483; W = 602.5; Z = −7.990; p < 0.001; r = 0.673). All 12 paired item comparisons remained significant after Bonferroni correction. No rural–urban item comparison remained significant after correction. In the adjusted model, rural placement was not associated with a statistically significant difference in the post-rotation score (β = 0.197, 95% CI −0.002 to 0.397; p = 0.053). Among the 86 rurally exposed students, the mean willingness to practice rurally was 2.87/5. The apparent association with career intention was not retained when excluding the overlapping career-likelihood item (11-item composite: H = 6.695, p = 0.153). Conclusions: Students reported more favourable perceptions after the rotation than they recalled having before it, but their willingness to practice rurally remained limited. The uncontrolled, retrospective design does not permit causal attribution, and the data do not establish a rural-placement advantage or subsequent specialty choice.
Background and Objectives: Family physicians are central to HPV vaccination delivery in Romania, yet little is known about how they perceive recent changes in parental attitudes and the barriers encountered in routine practice. We described these perceptions and examined factors associated with reporting a perceived change. Materials and Methods: A cross-sectional online survey of a non-probability convenience sample of 525 primary-care physicians was conducted in February 2025. Closed responses were summarised descriptively, free-text responses underwent structured thematic content analysis, and robust Poisson regression estimated adjusted prevalence ratios (aPRs), with nominal inference. Results: Amongst respondents, 82.9% reported perceiving a change in parental attitudes; 67.4% provided content meeting a conservative favourable-coding definition and 76.8% a broader definition. Safety concerns and fear (51.9%) and distrust or resistance (46.8%) were the most frequent barriers. Digital sources were perceived as the principal origins of myths (95.6%). Urban respondents reported perceived change more often than rural respondents (88.2% versus 69.9%; aPR 1.265, 95% CI 1.133–1.413; p < 0.001), with similar estimates across sensitivity analyses. Conclusions: In this convenience sample, most physicians reported perceiving changes in parental attitudes and many descriptions were coded as favourable. These reports generate hypotheses for studies using direct parental measures and documented vaccination outcomes.