Background: The fit accuracy of removable partial dentures (RPDs) is essential for the functionality, patient comfort, and durability of RPDs. Traditional fabrication methods, like lost-wax casting, are reliable, but labor intensive, potentially affecting the fit accuracy of RPDs. Advances in digital fabrication techniques offer new avenues to improve RPD precision. This systematic review and meta-analysis will assess the impact of digital fabrication methods on the fit accuracy of RPDs compared to conventional techniques. Objective: To evaluate whether digital fabrication methods, specifically CAD/CAM and additive manufacturing, offer superior fit accuracy for RPD frameworks over conventional methods. Methods: The study protocol was registered with PROSPERO (registration number CRD42024586891). A comprehensive literature search was conducted across PubMed, the Cochrane Library, Scopus, and Ovid MEDLINE databases, covering publications published up to July 2024. The inclusion criteria comprised in vitro studies comparing the fit accuracy of digital versus conventional RPD fabrication techniques, with quantitative outcomes, such as the mean gap size or seating accuracy. The data were extracted and synthesized using a random-effects meta-analysis model. Results: Eleven studies met the inclusion criteria, with seven studies included in the meta-analysis. The mean gap size for digitally fabricated RPDs was 140 µm, compared to 164 µm for conventional methods, with a weighted mean difference (WMD) of 26.29 µm, favoring digital techniques. The subgroup analysis indicated variability in the fit across different digital techniques, with milling showing the best results, although the differences were not statistically significant. Limitations: The analysis included only in vitro studies, limiting the clinical generalizability of the findings. Additionally, heterogeneity in the study design and measurement methods persisted, which could have impacted the overall conclusions. Conclusions: Digital fabrication methods demonstrated a trend toward improved fit accuracy in comparison to conventional techniques, although the differences were modest. Future research should focus on standardizing digital workflows and conducting clinical trials to confirm these findings.

Background/Aim: The purpose of this literature review and case report was to highlight the oral symptoms and the pathophysiology of Myasthenia Gravis (MG). MG is an autoimmune, antibody-mediated neuromuscular disorder. It is characterized by fluctuating fatigability and weakness affecting ocular, bulbar and (proximal) limb skeletal muscles. Case report: The case of an edentulous 72-year-old female patient with MG, and in need of removable prostheses was reported. The dental management of a complete denture wearer with MG required special attention and treatment protocols, as described in the present case report. Conclusions: Dental treatment, especially complete denture rehabilitation, of patients diagnosed with MG presents a challenge to the oral health care provider. Clinicians must be aware of the patients’ health status in order to preserve their natural dentition. Implant-supported overdentures must be the treatment of choice in cases of edentulism coupled with MG. In cases where a complete denture is the treatment option, the prosthesis should be placed in the zone of minimum conflict (neutral zone) for optimal neuromuscular coordination.

Background: Mandibular movement is inherently complex, involving both lateral and vertical components. In older adults, this complexity is compounded by diminished neuromuscular coordination and reduced proprioceptive feedback, often impairing effective mastication. Objectives: This study aimed to review dental literature on the influence of masticatory parameters in the formation of wear facets on acrylic resin denture teeth. Methods: A targeted literature review was conducted, analyzing peer-reviewed studies from 1991 to 2024 through PubMed and Scopus. The review focused on masticatory parameters, age-related neuromuscular adaptations, chewing patterns, and preferred-side denture tooth wear, affecting older adults using complete removable dentures. Results: Mandibular movement characteristics—particularly velocity, duration, and cycle frequency—were found to significantly influence denture tooth wear, often resulting in reduced bite force and masticatory efficiency. Contemporary denture materials demonstrated improved wear resistance, aiding in the regulation of chewing frequency and velocity. These factors are increasingly important as age-related changes impact the stomatognathic system. Notably, wear facets were most prominent on the maxillary first molars, regardless of the occlusal scheme. Conclusions: This review provided a comprehensive overview of existing research, analyzed current evidence, and offered insights into the role of masticatory function and wear characteristics in older complete denture wearers.