Background: Mandibular movement is inherently complex, involving both lateral and vertical components. In older adults, this complexity is compounded by diminished neuromuscular coordination and reduced proprioceptive feedback, often impairing effective mastication. Objectives: This study aimed to review dental literature on the influence of masticatory parameters in the formation of wear facets on acrylic resin denture teeth. Methods: A targeted literature review was conducted, analyzing peer-reviewed studies from 1991 to 2024 through PubMed and Scopus. The review focused on masticatory parameters, age-related neuromuscular adaptations, chewing patterns, and preferred-side denture tooth wear, affecting older adults using complete removable dentures. Results: Mandibular movement characteristics—particularly velocity, duration, and cycle frequency—were found to significantly influence denture tooth wear, often resulting in reduced bite force and masticatory efficiency. Contemporary denture materials demonstrated improved wear resistance, aiding in the regulation of chewing frequency and velocity. These factors are increasingly important as age-related changes impact the stomatognathic system. Notably, wear facets were most prominent on the maxillary first molars, regardless of the occlusal scheme. Conclusions: This review provided a comprehensive overview of existing research, analyzed current evidence, and offered insights into the role of masticatory function and wear characteristics in older complete denture wearers.

During cancer initiation, normal cells acquire mutations disrupting standard cellular processes, activating oncogenes and inactivating tumor suppressor genes, acquiring the well-described hallmarks of cancer on the path to malignancy. This process is influenced by a combination of physiological and metabolic pathways, as well as environmental cues, and leads to abnormal cell cycle, increased cell motility, and invasive characteristics. Cancer cell organelles also present some distinct differences from those of normal cells. Cancer progression requires certain tumorigenic biochemical pathways to be activated. However, mechanical cues are also important, as they have an effect on cell differentiation and fate. A continuous biochemical–biomechanical interaction exists, which affects the mechanical properties of the cells, as well as their behavior. This review aims to focus on the mathematical relationships governing cancer mechanobiology and examine how the altered mechanical properties of a cancer cell may affect malignant progression.

Selecting a post-and-core system for endodontically treated posterior teeth remains challenging. Cast post-and-core (CPC) and fiber post with composite resin core (FPCC) systems are used to restore structurally compromised teeth. Their biomechanical interactions with the remaining tooth structure under functional loading remain poorly understood. The purpose of this finite element analysis study was to assess how CPC and FPCC restorations influence internal stresses and interfacial stress distributions in a restored mandibular first molar under functional loading. A fully dentate mandibular model (W10532; 3B Scientific GmbH) was reconstructed using microcomputed tomography (TomoScope H; Werth Inc). A mandibular first molar was restored with a CPC or an FPCC, each supporting a complete coverage monolithic lithium disilicate crown. Finite element analysis simulated occlusal loading during masticatory function using physiologic loading vectors and validated boundary conditions. Anatomically accurate geometries and anisotropic material definitions were incorporated. The models were meshed with a converged finite element grid (<0.2%). Maximum principal stress was evaluated in enamel, dentin, bone, and periodontal ligament, while von Mises stress quantified internal post-and-core behavior. Stress and strain distributions were compared among restorations, with emphasis on internal post stresses and interfacial tensile stresses at the crown-core-post junction. The CPC model exhibited a 234% increase in internal post stresses compared to the FPCC model. Dentin stress levels remained similar between the systems, varying by about 4%. The FPCC model demonstrated a 15.2% increase in tensile stress at the crown-core-post interface and a 63.8% increase along the apical crown margin. These elevated interfacial stresses coincided with micromovement at bonded interfaces. Based on the findings of this finite element analysis study, CPC restorations concentrate higher internal stresses. In contrast, FPCC restorations reduce internal post stress but increase interfacial tensile stresses. Dentin stresses remained consistent across systems, indicating that the main difference is in failure mode.

Osteopetrosis is a rare hereditary disorder characterized by impaired osteoclastic bone resorption, resulting in generalized skeletal sclerosis, increased bone fragility, and a heightened risk of complications such as osteomyelitis. Prosthodontic rehabilitation in pediatric patients is particularly challenging due to ongoing craniofacial growth, incomplete dental development, and the need to avoid invasive procedures. A pediatric patient with osteopetrosis presented with mandibular Kennedy Class I, Modification I partial edentulism, misalignment of the maxillary teeth, and dentition at varying stages of development. A conservative removable prosthodontic approach was selected. Following tissue conditioning, a functional “washout” impression using a soft liner was performed to record the supporting tissues while minimizing pressure. To permit flexibility and future modification during growth, a removable partial denture (RPD) without a metal framework was fabricated. The impression surface was digitized using an intraoral scanner (TRIOS, 3Shape, Copenhagen, Denmark). The scan data guided computer‐aided design and milling of a new RPD from a monolithic polymethyl methacrylate (PMMA) disk (Ivotion, Ivoclar Vivadent AG, Schaan, Liechtenstein). The tissue‐borne prosthesis was extended to maximize support and contoured around the canines to provide encirclement and reciprocation, enhancing stability and retention while reducing stresses on abutment teeth. The digitally fabricated denture demonstrated an accurate intaglio fit, minimal intraoral adjustments, and improved esthetics and masticatory function. Its design allowed repeated tissue conditioning, incremental adaptation, and modifications to accommodate craniofacial growth. All digital scans were archived, enabling longitudinal superimposition to monitor growth‐related changes and facilitate early identification of pressure areas or sites at risk for osteomyelitis. Recall appointments were essential for growth adjustments and monitoring. Within the limitations of this case, an acrylic resin RPD without a metal framework represents a functional and adaptable interim solution for pediatric patients with osteopetrosis. The integration of digital workflows supports long‐term follow‐up and early complication detection during growth.

Rehabilitation of partially edentulous patients following fibular free-flap reconstruction presents significant functional and biomechanical challenges due to altered soft tissue morphology, reduced vestibular depth, and compromised load-bearing capacity. In cases involving extensive tissue loss, fixed prosthetic designs may be limited in their ability to support the tongue and cheeks, while implant-assisted removable partial dentures (IARPDs) offer better hygiene access and prosthetic flexibility. This case report describes a prosthetically driven approach that integrates CBCT-guided planning with advanced conventional prosthodontic techniques. After the fibula and overlying skin graft had sufficiently healed, a customized impression protocol was used to accommodate the irregular, highly resilient grafted soft tissues. Denture tooth placement was guided by the neutral zone concept to ensure functional harmony with the surrounding muscles. A radiographic splint with barium sulfate markers enabled prosthetically guided implant planning, resulting in the placement of three implants using a fully guided approach. A removable partial denture retained by stud attachments was selected, given the extent of tissue loss and the need for improved peri-implant hygiene. Intraoral activation of the attachments stabilized the distal extension during functional loading. Because the grafted tissues were mobile, a functional impression was performed to accurately capture the prosthetic-bearing area and facilitate relining, as conventional selective pressure techniques are insufficient in such conditions. The definitive prosthesis demonstrated improved retention, occlusal harmony, and functional stability, resulting in greater patient comfort and masticatory efficiency. This case highlights the potential value of prosthetically driven planning, functional impression techniques, and neutral zone-guided tooth placement in supporting functional rehabilitation and favorable clinical outcomes in reconstructed mandibles after oncologic resection.