Christos Nikitas

Dr. Christos Nikitas

orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 March 2022 in Journal of Frailty, Sarcopenia and Falls
Verified
Journal Article
Open access
CNChristos Nikitas
Christos Nikitas
DKDimitris Kikidis
Dimitris Kikidis
ABAthanasios Bibas
Athanasios Bibas
MPMarousa Pavlou
Marousa Pavlou
ZZZoi Zachou
Zoi Zachou
DBDoris-Eva Bamiou
Doris-Eva Bamiou
Physical inactivity and sedentary time are associated with all-cause mortality, chronic non-communicable diseases and falls in the elderly. Objective of this review is to assess and summarize recommendations from clinical guidelines for physical activity (PA) of older adults in general and related to falls. A scoping review of the existing clinical guidelines was conducted. The included studies should have been developed under the auspices of a health organization and their methodology should be described in detail. Nine clinical guidelines providing specific recommendations for the elderly were identified. There was a strong agreement across the guidelines regarding goals, activities parameters, adverse effects of PA, in addition to reference for preventing falls. Keeping even the minimum of physical activity, introducing balance exercises and strengthening exercises for preventing falls, avoiding unexpected accelerations in the intensity of the activities, applying the necessary precautions and consulting a health professional are the main pillars of recommendations. Despite any deficiencies in definitions, monitoring and optimal dosage consistency of recommendations, is an ideal incentive for countries and organizations to adopt and enhance physical activity as an antidote to the degeneration of human’s health and quality of life.

8 August 2017 in International Journal of Audiology
Verified
Journal Article
Closed access
CNChristos Nikitas
Christos Nikitas
DKDimitris Kikidis
Dimitris Kikidis
SKSpyros Katsinis
Spyros Katsinis
EKEfthymios Kyrodimos
Efthymios Kyrodimos
ABAthanasios Bibas
Athanasios Bibas
Objective: The aim of the study was to test the reliability and validity of the Dizziness Handicap Inventory in the Greek language (DHI). Design: This study was performed in a university tertiary centre. Internal consistency was estimated using Cronbach’s alpha for the DHI, physical (DHI-P), functional (DHI-F) and emotional (DHI-E) subscale scores. Correlation between DHI (total and subscales) and the SOT (sensory organisation test) as well as correlation between the DHI and FGA (functional gait assessment) was tested using Spearman’s correlation coefficient. Test–retest reliability was tested using ICC (Intraclass Correlation Coefficient). Sample size: Ninety (90) patients were included in the study. Results: Internal consistency was excellent for the total score and very good for the physical functional and emotional subscale scores. No statistically significant correlation was found between SOT and DHI. There was a moderate correlation between FGA and total DHI scores (r = −0.472; p < 0.0001) and poor to moderate between FGA and DHI subscale scores (DHI-E r1 = −0.342; p1 = 0.001, DHI-F r2 = −0.448 p2 < 0.0001, DHI-P r3 = −0.472 p3 < 0.0001). Test–retest reliability was excellent. Conclusion: Greek version of DHI is recommended as a valid measure for patients with vestibular disorders.

10 September 2021 in Otology & Neurotology
Verified
Journal Article
Closed access
ALAndreas Lilios
Andreas Lilios
TCTheognosia Chimona
Theognosia Chimona
CNChristos Nikitas
Christos Nikitas
CPChariton Papadakis
Chariton Papadakis
ICIoannis Chatziioannou
Ioannis Chatziioannou
CSCharalambos Skoulakis
Charalambos Skoulakis
Objective: The investigation of supervised vestibular rehabilitation treatment role for individuals with dizziness and imbalance due to peripheral, unilateral vestibular disorders. Databases Reviewed: Cochrane, PubMed, and Physiotherapy Evidence Database (PEDro) were utilized to identify relevant studies. Methods: The key search terms used were “Vestibular Rehabilitation and Unilateral Vestibular Hypofunction,” “Vestibular Rehabilitation and Unilateral Vestibular Loss,” and “Vestibular Rehabilitation and Supervision.” A manual search was performed by exploring the references of included articles to identify studies not captured through the computer-based searches. The quality of the studies was assessed according to the PEDro scale. Inclusion criteria were: 1) studies with patients, aged from 18 to 80 years, with acute or chronic dizziness and disequilibrium due to unilateral vestibular dysfunction, 2) randomized control trials (RCTs), 3) studies comparing supervised vestibular rehabilitation program with an unsupervised vestibular rehabilitation program or home-based training or standard care or placebo, and 4) articles written in the English language. Studies reporting cases of vertigo and imbalance due to possible recurrent pathologies, acute benign paroxysmal positional vertigo, or central neurological/orthopedic deficits, were excluded. Results: A total of 448 articles were retrieved from the systematic database search strategy. Five of them were included in the systematic review after full-text analysis, plus one more after manual searching of their references. All studies involved supervised vestibular rehabilitation treatment programs compared with unsupervised home training, the performance of daily activities and, standard care. Based on PEDro's scoring system, one study rated as high-quality RCT, three studies were considered of fair quality and one scored as low-quality RCT. Conclusions: Although most RCTs report better outcomes with a supervised vestibular rehabilitation treatment program regarding the emotional status, dizziness, and balance improvement, this systematic review failed to provide a strong evidence that supervision is superior to unsupervised protocols in patients with UNH. The self-reported subjective measures used by the included RCTs represent a serious limitation of their results.

1 October 2024 in Age and Ageing
Verified
Journal Article
Open access
PDF file
MPMarousa Pavlou
Marousa Pavlou
CFCarol Ann Flavell
Carol Ann Flavell
FMFariba Mostajeran
Fariba Mostajeran
CNChristos Nikitas
Christos Nikitas
DKDimitris Kikidis
Dimitris Kikidis
DBDoris-Eva Bamiou
Doris-Eva Bamiou
Background: Falls have high socioeconomic costs. Information and communication technologies may support provision and monitoring of multisensory (MSR) physiotherapy programmes. The HOLOBalance platform used augmented reality holograms to provide patient-centred, individualised MSR.Objectives: To determine the platform’s safety, acceptability and feasibility, investigate functional gait and dynamic balance benefits and provide data for a definitive trial.Design and setting: Single-blinded pilot randomised controlled feasibility study. Interventions were conducted at clinical sites or participants’ homes in three European countries.Participants: Community-dwelling older adults (median age 73 years; 64.2% female) at risk of falls were enrolled (May 2020-August 2021).Methods: Participants were randomised to an 8-week clinic or home-based telerehabilitation MSR or OTAGO (control group) programme. Compliance, satisfaction, and adverse events determined feasibility. Clinical outcomes, assessed (blinded) within one-week prior to and post-intervention, included functional gait assessment (FGA), Mini BESTest and cognitive function.Results: Randomisation to completion rate was 76.15% with 109 participants recruited (n = 289 screened). Drop-out rate was similar between groups. Adverse events were reported (n = 3) in the control group. Sixty-nine percent would recommend the HOLOBalance intervention. Findings were similar for the home and clinic-based arms of each intervention; data was combined for analysis. FGA (95%CI [1.63, 4.19]) and Mini-BESTest (95%CI [1.46, 3.93]) showed greater improvement in the HOLOBalance group with a clinically meaningful change of 4/30 noted for the FGA.Conclusions: HOLObalance was feasible to implement and acceptable to older adults at risk of falls, with FGA and Mini-BEST improvements exceeding those for the OTAGO programme. A definitive trial is warranted.

16 February 2023 in Otology & Neurotology
Verified
Journal Article
Closed access
ALAndreas Lilios
Andreas Lilios
TCTheognosia S. Chimona
Theognosia S. Chimona
CPChariton Papadakis
Chariton Papadakis
ICIoannis Chatziioanou
Ioannis Chatziioanou
CNChristos Nikitas
Christos Nikitas
CSCharalambos Skoulakis
Charalambos Skoulakis
Objective: To assess the effectiveness of three vestibular rehabilitation protocols in patients with chronic unilateral vestibular hypofunction. Study Design: Prospective randomized trial. Setting: Audiology-neurootology laboratory in a general public hospital. Patients: Eighty-one patients were randomly allocated into three groups: adaptation exercises (AEs), habituation exercises (HEs), and combined exercises (AE-HEs). Intervention(s): Each patient completed an 8-week vestibular rehabilitation program with exercise, depending on their allocation group. Main Outcome Measure(s): Evaluations performed at baseline, 4 weeks, and 8 weeks with (a) Functional Gait Assessment (FGA), (b) Mini-BESTest, (c) Vestibular Rehabilitation Benefit Questionnaire, and (d) Dizziness Handicap Inventory. Results: FGA and Mini-BESTest scores showed significant improvement between the baseline and 8-week scores in all groups (p < 0.001), except for the FGA score in the HE group. The AE-HE group showed better scores for all measurements at 4 weeks and had significantly better FGA and Mini-BESTest scores than the AE group and better FGA scores than the HE group. The Vestibular Rehabilitation Benefit Questionnaire and Dizziness Handicap Inventory scores in the AE-HE group were significantly better (p ≤ 0.001) than those in the HE group at 8 weeks. Conclusions: The AE-HE group showed faster improvement and significantly better outcomes for static balance, dynamic postural stability, and self-perceived disability than the single-exercise protocols in chronic unilateral vestibular hypofunction.

21 November 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
ALAndreas Lilios
Andreas Lilios
CNChristos Nikitas
Christos Nikitas
CSCharalampos Skoulakis
Charalampos Skoulakis
AAAggeliki Alagianni
Aggeliki Alagianni
JHJiannis Hajiioannou
Jiannis Hajiioannou
TCTheognosia S. Chimona
Theognosia S. Chimona
Background and Objectives: Unilateral vestibular hypofunction (UVH) in cases of insufficient central nervous system compensation leads to chronic dizziness. A customized vestibular rehabilitation (VR) program is more beneficial than a generic set of exercises for patients with chronic UVH. The purpose of the present study is to compare a customized remotely supervised VR program with a customized unsupervised VR program in chronic UVH patients. Methods: Participants were randomly allocated into two groups (Group A and Group B) and received an individualized 6-week home-based VR program that included adaptation and habituation exercises, balance and gait training. All individuals’ VR program implementation was evaluated weekly, allowing for exercise modifications. Moreover, Group A received additional remote supervision via phone communication (twice per week). The effectiveness of each VR program was evaluated using the scores of the Mini-BESTest, the Functional Gait Assessment (FGA), and the Dizziness Handicap Inventory (DHI). Results: At the 6-week assessment, participants in Group A had significantly better scores in objective and subjective evaluated parameters than those in Group B (p < 0.001). Group A also showed better compliance with the VR program. On the contrary, participants’ conformity in their individualized exercises was not affected by gender, duration of symptoms, or BMI (p > 0.05). Conclusions: Our clinical study highlights the advantages of using telephone communication, with a structured design and implementation, to assist individuals in successfully following a VR protocol.