Dormancy breakers are widely employed in regions with an insufficient chill accumulation to enhance floral bud break in sweet cherry production. Dormex (HC) has not been authorized in Europe and many other countries due to its detrimental effects on human health (carcinogenic) and the environment. This situation has increased the demand for alternative chemicals to HC. The current study was conducted in an orchard of 5-year-old ‘Royal Tioga^®’ sweet cherry trees (Prunus avium L.) grafted on MaxMa 14 rootstocks in the Karayusuflu Village (at an altitude of 50 m), Adana, a Mediterranean city in Türkiye. Levante (LV) and HC were applied approximately 30 days before the anticipated dormancy break of the buds. Chill accumulation was quantified monthly during the 2023–2024 winter season using the chilling hours below 7.2 °C (467 h) and chill units (280 CUs). This study evaluated the effects of dormancy breakers on hormonal changes in floral buds, focusing specifically on gibberellic acid (GA₃) and abscisic acid (ABA). Also, their impact on fruit set and quality parameters was assessed. The findings revealed that the LV and HC applications reduced the ABA content in flower buds during the dormancy period compared to the control. LV significantly improved bud break rates (56.8%) and fruit set (85.2%) while positively influencing the fruit quality parameters and yield. No significant differences between the LV and HC treatments were observed regarding average fruit weight (8.8–8.4 g) and yield values (3.7–3.5 kg tree⁻¹). These results suggest LV as an alternative to HC for early-season cherry production in warm climates.