This research investigated the effect of climate change on the two main river basins of Senegal in West Africa: the Senegal and Gambia River Basins. We used downscaled projected future rainfall and potential evapotranspiration based on projected temperature from six General Circulation Models (CanESM2, CNRM, CSIRO, HadGEM2-CC, HadGEM2-ES, and MIROC5) and two scenarios (RCP4.5 and RCP8.5) to force the GR4J model. The GR4J model was calibrated and validated using observed daily rainfall, potential evapotranspiration from observed daily temperature, and streamflow data. For the cross-validation, two periods for each river basin were considered: 1961–1982 and 1983–2004 for the Senegal River Basin at Bafing Makana, and 1969–1985 and 1986–2000 for the Gambia River Basin at Mako. Model efficiency is evaluated using a multi-criteria function (F_agg) which aggregates Nash and Sutcliffe criteria, cumulative volume error, and mean volume error. Alternating periods of simulation for calibration and validation were used. This process allows us to choose the parameters that best reflect the rainfall-runoff relationship. Once the model was calibrated and validated, we simulated streamflow at Bafing Makana and Mako stations in the near future at a daily scale. The characteristic flow rates were calculated to evaluate their possible evolution under the projected climate scenarios at the 2050 horizon. For the near future (2050 horizon), compared to the 1971–2000 reference period, results showed that for both river basins, multi-model ensemble predicted a decrease of annual streamflow from 8% (Senegal River Basin) to 22% (Gambia River Basin) under the RCP4.5 scenario. Under the RCP8.5 scenario, the decrease is more pronounced: 16% (Senegal River Basin) and 26% (Gambia River Basin). The Gambia River Basin will be more affected by the climate change.

The African horse sickness epizootic in Senegal in 2007 caused considerable mortality in the equine population and hence major economic losses. The vectors involved in the transmission of this arbovirus have never been studied specifically in Senegal. This first study of the spatial and temporal dynamics of the Culicoides (Diptera: Ceratopogonidae) species, potential vectors of African horse sickness in Senegal, was conducted at five sites (Mbao, Parc Hann, Niague, Pout and Thies) in the Niayes area, which was affected by the outbreak.

Rift Valley fever is an emerging mosquito-borne disease that represents a threat to human and animal health. The exophilic and exophagic behavior of the two main vector in West Africa (Aedes vexans and Culex poicilipes), adverse events post-vaccination, and lack of treatment, render ineffective the disease control. Therefore it is essential to develop an information system that facilitates decision-making and the implementation of adaptation strategies. In East Africa, RVF outbreaks are linked with abnormally high rainfall, and can be predicted up to 5 months in advance by modeling approaches using climatic and environmental parameters. However, the application of these models in West Africa remains unsatisfactory due to a lack of data for animal and human cases and differences in the dynamics of the disease emergence and the vector species involved in transmission. Models have been proposed for West Africa but they were restricted to rainfall impact analysis without a spatial dimension. In this study, we developed a mixed Bayesian statistical model to evaluate the effects of climatic and ecological determinants on the spatiotemporal dynamics of the two main vectors. Adult mosquito abundance data were generated from July to December every fortnight in 2005–2006 at 79 sites, including temporary ponds, bare soils, shrubby savannah, wooded savannah, steppes, and villages in the Barkédji area. The results demonstrate the importance of environmental factors and weather conditions for predicting mosquito abundance. The rainfall and minimum temperature were positively correlated with the abundance of Cx. poicilipes, whereas the maximum temperature had negative effects. The rainfall was negatively correlated with the abundance of Ae. vexans. After combining land cover classes, weather conditions, and vector abundance, our model was used to predict the areas and periods with the highest risks of vector pressure. This information could support decision-making to improve RVF surveillance activities and to implement better intervention strategies.

Logistic regression is widely used in medical studies to investigate the relationship between a binary response variable Y and a set of potential predictors X. The binary response may represent, for example, the occurrence of some outcome of interest (Y=1 if the outcome occurred and Y=0 otherwise). In this paper, we consider the problem of estimating the logistic regression model with a cure fraction. A sample of observations is said to contain a cure fraction when a proportion of the study subjects (the so-called cured individuals, as opposed to the susceptibles) cannot experience the outcome of interest. One problem arising then is that it is usually unknown who are the cured and the susceptible subjects, unless the outcome of interest has been observed. In this setting, a logistic regression analysis of the relationship between X and Y among the susceptibles is no more straightforward. We develop a maximum likelihood estimation procedure for this problem, based on the joint modeling of the binary response of interest and the cure status. We investigate the identifiability of the resulting model. Then, we establish the consistency and asymptotic normality of the proposed estimator, and we conduct a simulation study to investigate its finite-sample behavior.