Karen Brage

Dr. Karen Brage

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Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 May 2019 in BMJ Open
Verified
Journal Article
Open access
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KBKaren Brage
Karen Brage
JHJohn Hjarbaek
John Hjarbaek
PKPer Kjaer
Per Kjaer
KIKim Gordon Ingwersen
Kim Gordon Ingwersen
BJBirgit Juul-Kristensen
Birgit Juul-Kristensen
Objectives The reliability of ultrasonic strain elastography (SEL) used to detect abnormalities in the supraspinatus tendon is unclear. Thus, the aim of this study was to investigate the reliability of SEL in the supraspinatus tendon. Design An intra-rater and inter-rater reliability study. Setting A single-centre study conducted at the University of Southern Denmark. Participants Twenty participants with shoulder pain and MRI-verified supraspinatus tendinosis and 20 asymptomatic participants (no MRI). Primary and secondary outcome measures Raw values (RAW) and ratios (deltoid muscle (DELT) and gel pad (GEL) as reference tissues) were calculated and mean values of measurements from three regions of the supraspinatus tendon were reported. Colour scale ratings and number of yellow/red lesions from the three areas were also included. Results Intra-rater reliability showed intraclass correlation coefficients (ICCs) for RAW, DELT and GEL: 0.97 (minimal detectable change (MDC): 0.28 (6.36% of the mean)), 0.89 (MDC: 2.91 (20.37%)) and 0.73 (MDC: 1.61 (58.82%)), respectively. The ICCs for inter-rater reliability were 0.89 (MDC: 0.47 (10.53%)), 0.78 (MDC: 3.69 (25.51%)) and 0.70 (MDC: 1.75 (62.63%)), respectively. For colour scale ratings, intra-rater reliability (linear weighted kappa) ranged from 0.76 to 0.79, with the inter-rater reliability from 0.71 to 0.81. For the number of lesions, intra-rater reliability ranged from 0.40 to 0.82 and inter-rater reliability from 0.24 to 0.67. Conclusions Intra-rater and inter-rater reliability were excellent for raw values and for ratios with deltoid muscle as the reference tissue, and good for ratios with gel pad as the reference tissue. The reliability of colour scale ratings was substantial-to-almost perfect, and for the number of lesions fair-to-almost perfect. Although high reliability was found, validity and responsiveness of these elastographic methods needs further investigation. Ethics approval The study protocol was approved by the Ethics Committee for the Region of South Denmark (S-20160115) and reported to the Danish Data Protection Agency (2014-41-3266).

24 February 2020 in JSES International
Verified
Journal Article
Open access
KBKaren Brage
Karen Brage
JHJohn Hjarbaek
John Hjarbaek
EBEleanor Boyle
Eleanor Boyle
KIKim Gordon Ingwersen
Kim Gordon Ingwersen
PKPer Kjaer
Per Kjaer
BJBirgit Juul-Kristensen
Birgit Juul-Kristensen
We aimed to explore the discriminative validity of ultrasound strain elastography (SEL) between patients with painful supraspinatus tendinopathy and healthy control shoulders, as well as the associations between SEL and magnetic resonance imaging (MRI), conventional ultrasound (tendon thickness), and the Disabilities of the Arm, Shoulder and Hand questionnaire (DASH). Thirty patients with shoulder pain and MRI-verified supraspinatus tendinopathy and 30 healthy control shoulders (no pain) were examined using SEL, MRI, and conventional ultrasound of the supraspinatus tendon. SEL variables included raw data, ratios between the deltoid muscle and supraspinatus tendon (deltoid ratio), color rating, and presence of red/yellow lesions (middle, worst part, and total tendon). Statistically significant increases in odds ratios for being symptomatic (increased softening) were seen for all raw data variables, corresponding to 3.978 (95% confidence interval [CI], 1.414-11.197) for middle, 4.602 (95% CI, 1.536-13.788) for worst, and 4.865 (95% CI, 1.406-16.836) for total tendon, and 1.260 (95% CI, 1.027-1.545) for the deltoid ratio (worst), adjusted for sex and body mass index (BMI). Tendon thickness was not associated with SEL; however, significantly positive associations were found between raw data variables and MRI (β ≥ 0.58, P < .01), and positive associations were found between raw data variables and the DASH score (β = 0.01, P ≤ .04), adjusted for sex and BMI. Raw data variables and the deltoid ratio (worst) discriminated between patients with painful supraspinatus tendinopathy and healthy control shoulders when adjusted for sex and BMI. Associations were statistically significant for raw data variables and MRI or DASH score when adjusted for sex and BMI. Further studies are needed to understand SEL and the role of sex and BMI, including the responsiveness of SEL.

10 February 2024 in Radiography
Verified
Journal Article
Open access
Malene Roland Vils PedersenMalene Roland Vils Pedersen
Malene Roland Vils Pedersen
HPHelle Precht
Helle Precht
JJJanni Jensen
Janni Jensen
BMBo Mussmann
Bo Mussmann
Ahmed Jibril AbdiAhmed Jibril Abdi
Ahmed Jibril Abdi
KBKaren Brage
Karen Brage
Social media (SoMe) is widely used as a communication platform in everyday life. Also, healthcare professionals have embraced SoMe as a communication tool for both peers and patients. It is becoming an interactive tool for discussing professionals' issues and a place where learning and education occur. This study explores the specific patterns of SoMe use for radiographers' in the Nordic countries. The aim of this survey was to investigate radiographers use of social platforms in a professional setting. A 29-item survey was prepared, and pilot-tested. The survey was produced in Danish a language that all Nordic countries master. In general, most Nordic languages are very similar. The survey was distributed by online platforms such as Facebook, LinkedIn, Twitter/X, and also distributed by newsletters by the Norwegian and Danish national radiographers societies. All data was collected anonymously. An Ethical Research approval was obtained from the University of Southern Denmark. A total of 242 respondents completed the survey (Denmark n = 183, Norway n = 48, Sweden n = 8, and n = 3 from other Scandinavian countries). The respondents included 186 females, 52 males and four were undisclosed. On average, the respondents spent approximately 2 h and 23 min daily on SoMe, with 27 min specifically dedicated to content relevant to radiographers. Facebook was the preferred platform with 93 % (n = 226). A total of 5.4 % (n = 13) respondents had experienced contact from patients and/or next of kin, while 92 % (n = 222) reported no such interactions and 2.9 % (n = 7) were undisclosed. A total of 52.8 % (n = 128) used SoMe in relation to courses, conferences, or online meetings. This shows that time spent on content relevant to radiographers imply that SoMe can be a relevant tool for reaching radiographers. The survey demonstrates radiographers' use of SoMe for personal and professional interest, with Facebook as the preferred social media platform. SoMe were mostly used during courses, conferences, or online meetings with half of the respondent reported using SoMe platforms during working hours. These results underscore the untapped potential of SoMe in professional healthcare settings. Additionally, the study offers insight into current practices, facilitating comparisons to identify trends in SoMe usage within the radiographer community. The findings advocate for the strategic use of SoMe by radiographers', emphasizing professional networking and knowledge sharing. However, clear guidelines are necessary to ensure patient confidentiality and data security in these digital interactions.

3 May 2023 in WFUMB Ultrasound Open
Verified
Journal Article
Open access
KBKaren Brage
Karen Brage
KPKristina T.T. Pank
Kristina T.T. Pank
SHSisse Hansen
Sisse Hansen
LSLis K. Sondergaard
Lis K. Sondergaard
MMMark F McEntee
Mark F McEntee
MPMalene Roland V. Pedersen
Malene Roland V. Pedersen

19 February 2025 in Radiography
Verified
Journal Article
Open access
KBKaren Brage
Karen Brage
Malene Roland Vils PedersenMalene Roland Vils Pedersen
Malene Roland Vils Pedersen
CLC.A. Lauridsen
C.A. Lauridsen
CPC. Paulo
C. Paulo
PHP. Hansen
P. Hansen
JJJanni Jensen
Janni Jensen
The aim of this literature review is to provide an overview and synthesize the evidence on the role of reporting radiographers in CT and MRI, with a focus on their diagnostic accuracy, the education and training required for this role, and the challenges and opportunities associated with their integration into clinical practice. Radiographers in CT and MRI reporting roles often achieve diagnostic accuracy comparable to radiologists, particularly for straightforward pathologies and as first readers. However, discrepancies are more common in complex cases, such as extracolonic findings in CT colonography or smaller polyps in MR colonography. Structured training, including postgraduate certificates, tele-training, and technology-enhanced learning, enhances radiographers' diagnostic accuracy and confidence. However, regional variation in training availability and standardisation limits broader implementation. Challenges to integration include legal and regulatory constraints, geographical training disparities, and concerns about misdiagnosis. Regular audits and mentoring are crucial to ensuring quality and addressing these concerns. Radiographers have demonstrated the ability to achieve diagnostic performance comparable to radiologists in specific contexts, particularly when supported by structured training and mentorship. However, challenges such as variability in training opportunities, legal and regulatory constraints, and the risk of misdiagnosis persist. While the evidence highlights the potential of radiographer-led reporting to enhance diagnostic workflows, reduce radiologist workloads, and improve patient care, further research is needed to address these challenges and evaluate long-term impacts on clinical outcomes. Healthcare organisations should implement standardised training pathways to prepare radiographers for reporting roles. Collaborative models, where radiographers support rather than replace radiologists, can improve efficiency while maintaining quality. Policymakers must provide clear guidelines and funding to expand these roles, particularly in radiologist-shortage areas. Technological tools, such as AI-assisted reporting, can help radiographers manage complex cases. Equitable training opportunities, including remote learning and mobile apps, should address geographical disparities. Robust quality assurance protocols are essential to sustain confidence in radiographer-led reporting and enhance patient care outcomes.