We propose a methodology to aid clinicians in performing lumbar spinal stenosis detection through semantic segmentation and delineation of Magnetic Resonance Imaging (MRI) scans of lumbar spine using deep learning. Our dataset contains MRI studies of 515 patients with symptomatic back pains. Each study is annotated by expert radiologists with notes regarding the observed characteristics and condition of the lumbar spine. We have developed a ground truth dataset, containing image labels of four important regions in the lumbar spine, to be used as training and test images to develop classification models for segmentation. We developed two novel metrics, namely confidence and consistency, to assess the quality of the ground truth dataset through a derivation of the Jaccard Index. We experimented with semantic segmentation of our dataset using SegNet. Our evaluation of the segmentation and the delineation results show that our proposed methodology produces very good performance as measured by several contour-based and region-based metrics. Additionally, using the Cohen’s kappa and frequency-weighted confidence metrics, we can show that 1) the model’s performance is within the range of the worst and the best manual labelling results, and 2) the ground-truth dataset has an excellent inter-rater agreement score. We also presented two representative delineation results of the worst and best segmentation based on their BF-score to show visually how accurate and suitable the results are for computer-aided-diagnosis purposes.
In this paper, a novel application of machine learning algorithms including Neural Network architecture is presented for the prediction of flood severity. Floods are considered natural disasters that cause wide-scale devastation to areas affected. The phenomenon of flooding is commonly caused by runoff from rivers and precipitation, specifically during periods of extremely high rainfall. Due to the concerns surrounding global warming and extreme ecological effects, flooding is considered a serious problem that has a negative impact on infrastructure and humankind. This paper attempts to address the issue of flood mitigation through the presentation of a new flood dataset, comprising 2000 annotated flood events, where the severity of the outcome is categorised according to 3 target classes, demonstrating the respective severities of floods. The paper also presents various types of machine learning algorithms for predicting flood severity and classifying outcomes into three classes, normal, abnormal, and high-risk floods. Extensive research indicates that artificial intelligence algorithms could produce enhancement when utilised for the pre-processing of flood data. These approaches helped in acquiring better accuracy in the classification techniques. Neural network architectures generally produce good outcomes in many applications, however, our experiments results illustrated that random forest classifier yields the optimal results in comparison with the benchmarked models.
Lumbar Spinal Stenosis causes low back pain through pressures exerted on the spinal nerves. This can be verified by measuring the anteroposterior diameter and foraminal widths of the patient’s lumbar spine. Our goal is to develop a novel strategy for assessing the extent of Lumbar Spinal Stenosis by automatically calculating these distances from the patient’s lumbar spine MRI. Our method starts with a semantic segmentation of T1- and T2-weighted composite axial MRI images using SegNet that partitions the image into six regions of interest. They consist of three main regions-of-interest, namely the Intervertebral Disc, Posterior Element, and Thecal Sac, and three auxiliary regions-of-interest that includes the Area between Anterior and Posterior elements. A novel contour evolution algorithm is then applied to improve the accuracy of the segmentation results along important region boundaries. Nine anatomical landmarks on the image are located by delineating the region boundaries found in the segmented image before the anteroposterior diameter and foraminal widths can be measured. The performance of the proposed algorithm was evaluated through a set of experiments on the Lumbar Spine MRI dataset containing MRI studies of 515 patients. These experiments compare the performance of our contour evolution algorithm with the Geodesic Active Contour and Chan-Vese methods over 22 different setups. We found that our method works best when our contour evolution algorithm is applied to improve the accuracy of both the label images used to train the SegNet model and the automatically segmented image. The average error of the calculated right and left foraminal distances relative to their expert-measured distances are 0.28 mm (p = 0.92) and 0.29 mm (p = 0.97), respectively. The average error of the calculated anteroposterior diameter relative to their expert-measured diameter is 0.90 mm (p = 0.92). The method also achieves 96.7% agreement with an expert opinion on determining the severity of the Intervertebral Disc herniations.
Artificial Intelligence through supervised machine learning remains an attractive and popular research area in medical image processing. The objective of such research is often tied to the development of an intelligent computer aided diagnostic system whose aim is to assist physicians in their task of diagnosing diseases. The quality of the resulting system depends largely on the availability of good data for the machine learning algorithm to train on. Training data of a supervised learning process needs to include ground truth, i.e., data that have been correctly annotated by experts. Due to the complex nature of most medical images, human error, experience, and perception play a strong role in the quality of the ground truth. In this paper, we present the results of annotating lumbar spine Magnetic Resonance Imaging images for automatic image segmentation and propose confidence and consistency metrics to measure the quality and variability of the resulting ground truth data, respectively.
Many lumbar spine diseases are caused by defects or degeneration of lumbar intervertebral discs (IVD) and are usually diagnosed through inspection of the patient’s lumbar spine MRI. Efficient and accurate assessments of the lumbar spine are essential but a challenge due to the size of the clinical radiologist workforce not keeping pace with the demand for radiology services. In this paper, we present a methodology to automatically annotate lumbar spine IVDs with their height and degenerative state which is quantified using the Pfirrmann grading system. The method starts with semantic segmentation of a mid-sagittal MRI image into six distinct non-overlapping regions, including the IVD and vertebrae regions. Each IVD region is then located and assigned with its label. Using geometry, a line segment bisecting the IVD is determined and its Euclidean distance is used as the IVD height. We then extract an image feature, called self-similar color correlogram, from the nucleus of the IVD region as a representation of the region’s spatial pixel intensity distribution. We then use the IVD height data and machine learning classification process to predict the Pfirrmann grade of the IVD. We considered five different deep learning networks and six different machine learning algorithms in our experiment and found the ResNet-50 model and Ensemble of Decision Trees classifier to be the combination that gives the best results. When tested using a dataset containing 515 MRI studies, we achieved a mean accuracy of 88.1%.