In this paper, the calculation model and method of the lubrication performance of the thrust bearing, which considers the thermal bomb deformation, are constructed based on the working characteristics of the main pump thrust of the nuclear power plant. The key design parameters of the tile package Angle θ are analyzed by taking the design parameters of the thrust-bearing tile as the variable. The circumferential fulcrum coefficient of tile, the influence of tile thickness B, and tile elastic modulus E on the lubrication performance of thrust bearing are analyzed to obtain improved design parameters. The lubrication performance of the thrust bearing includes the minimum oil film thickness h_min, the maximum temperature of oil film T_max, total flow Q_x, total power consumption W, maximum thermal deformation of axial bush δT_max, and the maximum elastic deformation of the axial bush δF_max. The scale test of the designed thrust bearing is carried out. The take-off speed of the bearing is tested and compared with the results of the theoretical analysis. The study results show that the influence is becoming more obvious from θo to h_min. Moreover, the impact becomes more obvious from T_max to Q_x, B to hmin, and Q_x to δT_max and δF_max. Lastly, the impact is also obvious from E to Q_x and δF_max.