Alireza Nasirzadeh

Dr. Alireza Nasirzadeh


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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27 June 2023 in Biomimetics
Verified
Journal Article
Open access
PDF file
ANAlireza Nasirzadeh
Alireza Nasirzadeh
JYJaeha Yang
Jaeha Yang
SYSeungtae Yang
Seungtae Yang
JYJuseok Yun
Juseok Yun
YBYoung Yoon BAE
Young Yoon BAE
Giuk LeeGiuk Lee
Giuk Lee
High-collar shoes are a biomimetic approach to preventing lateral ankle injuries during high-demand activities; however, the influence of collar stiffness (CS) on parameters related to lateral ankle sprain prevention during running remains unclear. In this study, we investigated the effects of a custom-designed shoe CS on muscular activity, dynamic stability, and leg stiffness (Kleg) during running using a biomimetic design approach inspired by the mechanisms of ankle sprain prevention. Sixteen healthy male participants ran on a treadmill while wearing a custom-designed high-collar shoe with low, medium, and high CS conditions, measured using circumferential ankle pressure (CAP). Lower extremity kinematics and electromyography (EMG) data were recorded simultaneously. One-way repeated-measures ANOVA was conducted to compare the CS conditions. Results indicate that high and medium CS conditions significantly reduce sagittal and frontal ankle ranges of motion (ROMs) compared to the low CS condition, providing improved stability and support against lateral ankle sprain; moreover, there was a trend towards higher dynamic stability and Kleg with increasing CS. Our study highlights the importance of considering the CAP in regulating high-collar stiffness properties and how higher CS may provide better support for the ankle during running. Nevertheless, additional research is necessary to validate the efficacy of the current design in preventing ankle sprains during high-demand activities.

9 December 2024 in Bioengineering
Verified
Journal Article
Open access
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YKYoosun Kim
Yoosun Kim
SPSEJUN PARK
SEJUN PARK
SYSeungtae Yang
Seungtae Yang
ANAlireza Nasirzadeh
Alireza Nasirzadeh
Giuk LeeGiuk Lee
Giuk Lee
This pilot study explored how muscle activation influences the pattern recognition of tactile cues delivered using electrical stimulation (ES) during each 10% window interval of the normal walking gait cycle (GC). Three healthy adults participated in the experiment. After identifying the appropriate threshold, ES as the haptic cue was applied to the gastrocnemius lateralis (GL) and biceps brachii (BB) of participants walking on a treadmill. Findings revealed variable recognition patterns across participants, with the BB showing more variability during walking due to its minimal activity compared to the actively engaged GL. Dynamic time warping (DTW) was used to assess the similarity between muscle activation and electro-stimulated haptic perception. The DTW distance between electromyography (EMG) signals and muscle recognition patterns was significantly smaller for the GL (4.87 ± 0.21, mean ± SD) than the BB (8.65 ± 1.36, mean ± SD), showing a 78.6% relative difference, indicating that higher muscle activation was generally associated with more consistent haptic perception. However, individual differences and variations in recognition patterns were observed, suggesting personal variability influenced the perception outcomes. The study underscores the complexity of human neuromuscular responses to artificial sensory stimuli and suggests a potential link between muscle activity and haptic perception.

16 August 2025 in Biomimetics
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Journal Article
Open access
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ECEunbin Choe
Eunbin Choe
JMJunyoung Moon
Junyoung Moon
JRJaewook Ryu
Jaewook Ryu
SYSeungtae Yang
Seungtae Yang
ANAlireza Nasirzadeh
Alireza Nasirzadeh
Giuk LeeGiuk Lee
Giuk Lee
Acute ankle sprains frequently lead to chronic ankle instability and muscle atrophy by causing immobilization, which necessitates real-time stiffness modulation for ankle–foot orthoses (AFOs). This paper proposes Active Variable Compression Shoes (AVC-Shoes), an ankle support system inspired by the “heel-lock taping” technique, which employs a wire–fabric compression mechanism to selectively stiffen ankle joints at crucial points in the gait cycle. The experimental results confirmed that AVC-Shoes achieve variable ankle stiffness in all directions, demonstrating dorsiflexion and plantarflexion stiffness ranges of up to 8.3 and 5.9 Nm/rad, respectively. Additionally, preliminary human testing involving three healthy participants revealed that the gastrocnemius muscle activity during the push-off phase in the active compression mode was significantly higher (by 19%) than that in the brace mode. By selectively increasing stiffness at heel strikes, AVC-Shoes represent a promising advancement toward next-generation AFOs capable of stabilizing the ankle while preventing muscle atrophy, which is associated with prolonged brace use.

1 February 2026 in Biomimetics
Verified
Journal Article
Open access
PDF file
CPCheonkyu Park
Cheonkyu Park
ANAlireza Nasirzadeh
Alireza Nasirzadeh
KLKiho Lee
Kiho Lee
GKGyeongmo Kim
Gyeongmo Kim
Giuk LeeGiuk Lee
Giuk Lee
Wearable robots can improve human walking economy; however, their effectiveness depends on user adaptation to assistance. This study introduces a framework for real-time estimation of user adaptation that relies only on wearable sensor data during operation. Metabolic measurements were used solely to establish the ground truth adaptation curves for model training and validation but are not required for real-time inference. Five healthy adults completed six days of treadmill walking while wearing a soft hip exosuit that provided hip extension assistance. Thigh-mounted inertial measurement units recorded step timing and hip-angle trajectories, from which three variability-based features (step-frequency variability, maximum hip-flexion variability, and maximum hip-extension variability) were extracted. A Long Short-Term Memory (LSTM) model used these gait-variability inputs to estimate each user’s adaptation level relative to a metabolic cost benchmark obtained from respiratory gas analysis. Across sessions, the metabolic cost decreased by 9.0 ± 5.6% from Day 1 to Day 6 (p < 0.01) with a mean time constant of 202 ± 78 min, In contrast, the variability in step frequency, maximum hip flexion, and maximum hip extension decreased by 66.4 ± 6.8%, 37.9 ± 24.2%, and 42.8 ± 10.6%, respectively, indicating that these reductions were users’ progressive adaptation to the exosuit’s assistance. Under leave-one-subject-out (LOSO) evaluation across five participants, 59.2% of the model predictions fell within ±10 percentage points of the metabolic cost–based adaptation curve. These results suggest that simple kinematic variability measured with wearable sensors can track user adaptation and support practical approaches to real-time monitoring. Such capability can facilitate adaptive control and training protocols that personalize exosuit assistance.