Background: Glaucoma and diabetic retinopathy are the leading causes of blindness due to an irreversible damage to the retina which results in vision loss. Early detection of these diseases through regular screening is especially important to prevent progression. The image of retinal fundus is the main evaluating strategy for the glaucoma and diabetic retinopathy detection. Then, automated eye disease detection is an important application of retinal image analysis. Compared with classical diagnostic techniques, image classification by convolutional neural networks (CNN) have the potential for better cost-effective performance. Methods: In this paper, we propose the use of MATLAB – retrained AlexNet CNN for computerized eye diseases identification, particularly glaucoma and diabetic retinopathy, by employing retinal fundus images. The acquisition of the database was carried out through free access databases and access upon request. A transfer learning technique is used for retraining the AlexNet CNN. Specifically, the model divides the fundus image dataset into training and testing data. Results: As datasets were added by network training, different values were reported for validation accuracy, false positives and false negatives, precision, and recall. Thus, having NetTransfer I with a validation accuracy value of 94.3% for two classes. NetTransfer II with a validation accuracy value of 91.8% for two classes. NetTransfer III with a validation accuracy value of 89.7% for three classes. Net transfer IV with a validation accuracy value of 93.1% for three classes. Finally, NetTransfer V with a validation accuracy value of 92.1% for three classes. Conclusions: Re-training of the AlexNet network proved to be a powerful tool to create disease detection systems having high accuracy values and being able to discern between more than two diseases.
Low back pain (LBP) is a highly common musculoskeletal condition and the leading cause of work absenteeism. This project aims to develop a medical test to help healthcare professionals decide on and assign physical treatment for patients with nonspecific LBP. The design uses machine learning (ML) models based on the classification of motion capture (MoCap) data obtained from the range of motion (ROM) exercises among healthy and clinically diagnosed patients with LBP from Imbabura–Ecuador. The following seven ML algorithms were tested for evaluation and comparison: logistic regression, decision tree, random forest, support vector machine (SVM), k-nearest neighbor (KNN), multilayer perceptron (MLP), and gradient boosting algorithms. All ML techniques obtained an accuracy above 80%, and three models (SVM, random forest, and MLP) obtained an accuracy of >90%. SVM was found to be the best-performing algorithm. This article aims to improve the applicability of inertial MoCap in healthcare by making use of precise spatiotemporal measurements with a data-driven treatment approach to improve the quality of life of people with chronic LBP.
Usually, cardiac pathologies are detected using one-dimensional electrocardiogram signals or two-dimensional images. When working with electrocardiogram signals, they can be represented in the time and frequency domains (one-dimensional signals). However, this technique can present difficulties, such as the high cost of private health services or the time the public health system takes to refer the patient to a cardiologist. In addition, the variety of cardiac pathologies (more than 20 types) is a problem in diagnosing the disease. On the other hand, surface electrocardiography (sECG) is a little-explored technique for this diagnosis. sECGs are three-dimensional images (two dimensions in space and one in time). In this way, the signals were taken in one-dimensional format and analyzed using neural networks. Following the transformation of the one-dimensional signals to three-dimensional signals, they were analyzed in the same sense. For this research, two models based on LSTM and ResNet34 neural networks were developed, which showed high accuracy, 98.71% and 93.64%, respectively. This study aims to propose the basis for developing Decision Support Software (DSS) based on machine learning models.
Background Glaucoma and diabetic retinopathy (DR) are the leading causes of irreversible retinal damage leading to blindness. Early detection of these diseases through regular screening is especially important to prevent progression. Retinal fundus imaging serves as the principal method for diagnosing glaucoma and DR. Consequently, automated detection of eye diseases represents a significant application of retinal image analysis. Compared with classical diagnostic techniques, image classification by convolutional neural networks (CNN) exhibits potential for effective eye disease detection. Methods This paper proposes the use of MATLAB – retrained AlexNet CNN for computerized eye diseases identification, particularly glaucoma and diabetic retinopathy, by employing retinal fundus images. The acquisition of the database was carried out through free access databases and access upon request. A transfer learning technique was employed to retrain the AlexNet CNN for non-disease (Non_D), glaucoma (Sus_G) and diabetic retinopathy (Sus_R) classification. Moreover, model benchmarking was conducted using ResNet50 and GoogLeNet architectures. A Grad-CAM analysis is also incorporated for each eye condition examined. Results Metrics for validation accuracy, false positives, false negatives, precision, and recall were reported. Validation accuracies for the NetTransfer (I-V) and netAlexNet ranged from 89.7% to 94.3%, demonstrating varied effectiveness in identifying Non_D, Sus_G, and Sus_R categories, with netAlexNet achieving a 93.2% accuracy in the benchmarking of models against netResNet50 at 93.8% and netGoogLeNet at 90.4%. Conclusions This study demonstrates the efficacy of using a MATLAB-retrained AlexNet CNN for detecting glaucoma and diabetic retinopathy. It emphasizes the need for automated early detection tools, proposing CNNs as accessible solutions without replacing existing technologies.